For each woman, the long-awaited pregnancy is a great joy, and, being pregnant, women care a lot about the health of their unborn child. During all three trimesters of pregnancy, each pregnant woman is prescribed a huge number of different tests, just to make sure that the fetus is fine. Analyzes are taken repeatedly, however, if the attending physician prescribes the delivery of the same analysis more often than others, it makes you wonder and often causes concern. One such test is a study on the amount of hCG in the mother's body. Most often it is HCG that tells us about pregnancy in the very first weeks.
What is hCG
Chorionic gonadotropin or hCG is a “pregnancy hormone” that refers to gonadotropic hormones, in contrast to luteinizing and follicle-stimulating hormones, it has a different amino acid sequence.
HCG, that is, human chorionic gonadotropin, is a rather unique hormone. It leaves the chorion (embryo shell) after the fertilized egg is implanted in the woman's uterus, about 5-6 days after fertilization. The presence, or vice versa, the absence of such a hormone in the blood just tells us that the fetus begins to develop in the uterus, that is, the pregnancy has begun. Usually, this analysis during the entire time of gestation can prompt us about the presence of various abnormalities in the development of the baby, or convince us that the pregnancy proceeds normally, therefore, hCG analysis must be carried out at various periods of the future child's development.
But you should also know that the increased rate of hCG can be observed not only in pregnant women. An increase in hCG in the blood and a positive pregnancy test in men and non-pregnant women indicates the presence of a hormone-producing tumor in the body. In addition, an increase in this hormone tells us that a woman has recently had an abortion.
The hormone hCG consists of alpha and beta subunits, and it is the beta particle that has a special structure; therefore, it is precisely that which is sought in the blood of a woman to establish pregnancy in the early period.
Why pass the analysis to determine HCG?
With the help of hCG in the blood, or rather in the plasma, you can accurately determine the date of conception. In the absence of menstruation on the second or third day, such an analysis can be done; if the term of conception is from six days, the results may be positive. In order to accurately verify the pregnancy, doctors advise again, after two or three days, to pass the analysis, as well as an ultravaginal ultrasound. When testing for HCG, do not eat at least four hours before donating blood. It is also required to inform the doctor in advance about possible hormonal medication. The determination of the presence of abnormalities in the development of a child for the analysis of hCG is sent from the fourteenth week of gestation.
Approximately the same rapid tests for pregnancy. The only difference between the analysis and the test is that the level of hCG is measured in urine (urine), rather than in the blood of a girl. However, if we compare the usual rapid test with a blood test for a hormone produced in the laboratory, we can conclude that the test will be much more effective not only because of laboratory tests, but also because of the higher content of hCG in the blood ( twice as much).
Growth of hCG for pregnancy test on days after fertilization
Norm hCG during pregnancy
After its formation, the chorion begins to secrete gonadotropin. The increase in the content of such a hormone in the body tells us about fertilization and the subsequent development of pregnancy. It happens pretty quickly. During the first trimester of pregnancy, the hCG rate doubles in two days. It reaches its highest rate from the seventh to the tenth week of pregnancy, after which the level of the hormone decreases, and remains so until the second half of the pregnancy.
From the growth rate of the hormone level in the woman’s body, the doctor can determine if the fetus is developing correctly and if there are any defects. Approximately from the fourteenth to the eighteenth week, the number of hCG will suggest the presence of pathologies in the development of the unborn child. In other words, such an analysis can only be called an ordinary precautionary measure; such an analysis should be taken calmly. After conducting a series of studies, the doctor makes a conclusion, where this analysis is assigned to far from the last role. In men and non-pregnant women, hCG is about five mIU / l, and in pregnant women, this figure always changes.
What are the abnormalities of hCG during pregnancy?
During the entire period of pregnancy, the hCG indicator may deviate from the norm on either side, which is undoubtedly not a very good fact. Both an increased and a reduced amount of hCG in the blood of a pregnant woman makes it clear about a violation of fetal development, or about the appearance of complications. The increased rate of hCG tells us about pregnancy with several embryos at once, as well as gestosis, possible toxicosis and the presence of various pathologies. In addition, this can be observed in women with diabetes, or taking synthetic gestagens. The reduced hCG indicator may speak to us as an ectopic pregnancy, a missed abortion, a lag in the development of the fetus, as well as the likelihood of self-abortion, embryo growth too slow, chronic placental insufficiency and prolonged pregnancy.
In addition to all the above, deviations from the norm in such an analysis can be observed when the duration of pregnancy is not entirely correct. HCG may not be present in the blood of the subject at all, which indicates that the analysis is too early, or may indicate ectopic pregnancy. You should also take into account the fact that a well-done analysis will show more truthful results.
How is HCG analysis performed?
Recommendations for the analysis of the analysis discusses the doctor when giving direction. But the general recommendations for blood tests for hCG are as follows: a test for b-hCG should be done on an empty stomach, regardless of the time of day. You should not drink or eat before taking the test, at least between four and six hours. Inform the technician and your doctor beforehand if you are taking hormones.
To study the level of the hormone hCG in the blood, the analysis is taken from a vein, the blood obtained is sent to the laboratory. To avoid a bruise at the puncture site, the hand should be firmly pressed and held for 5 minutes in this state. For the sake of more reliable results, experienced specialists will insist that you do not exercise before taking blood. You do not need to panic if your doctor will prescribe a lot of other tests, because they are done in order to make a diagnosis and identify possible risks and health problems.
Why the terms of pregnancy set by doctors do not coincide with the conclusions on the analysis of hCG
The term established by the results of the analysis of hCG is measured from the moment of conception and shows the age of the embryo, as well as the ultrasound readings. And the period, which is calculated by the gynecologist, is the obstetric term of pregnancy, it starts from the first day of the last menstruation, when there is no pregnancy and lags on average by about 2 weeks from the time of conception.
Why pregnancy tests are wrong
Mostly unreliable results are obtained for technical reasons. Firstly, the test itself may be “spoiled” (expired, improper storage or factory marriage), and secondly, the test may not be carried out according to the instructions.
A false-negative result may be with kidney diseases and with the use of diuretic drugs, with the pathology of pregnancy, and false-positive with hormonal disorders and diseases.
What can affect hCG levels?
In the absence of pregnancy, an increased rate of hCG may indicate various diseases, such as:
• tumors of the lungs, kidneys, testicles or ovaries, uterus, chorionic carcinoma, and other neoplasms,
• hormone-based treatment
• the remaining hormones of hCG in the blood after an abortion or from a previous gestation.
What can cause an increase in hCG
An increase in the concentration of hCG in pregnant women may indicate:
• diabetes of a pregnant woman,
• gestation of several embryos at once (the rise in the value of the hormone hCG is proportional to the number of embryos, i.e. the rate of hCG with twins will be 2 times more),
• taking synthetic progestin drugs
• discrepancy in the estimated and real term of carrying,
• preeclampsia and early toxicosis,
• during menopause there may be bursts of hormone production,
• chromosomal abnormalities in the fetus.
What can cause a decrease in hCG
In the case of a reduced indicator of human chorionic gonadotropin, it is possible to immediately conclude that the term for carrying a child is incorrectly established (one of the probable reasons is inconsistency in menstrual cycles). In addition, in the case of a sharp decrease, or a slow increase in the level of hCG, attention should be paid to such pathologies as:
• antenatal death of a child (around the second - third trimester),
• chronic placental insufficiency,
• the risk of miscarriage (only if the level of hCG is reduced by more than half compared to the usual rate),
• embryo development outside the uterus,
HCG concentration and pregnancy
Chorionic gonadotropin (CG, HCG) is a hormone produced by the placenta (chorion) since the embryo attaches to the walls of the uterus. More precisely, it begins to be produced from the first hours after the merger of the egg and sperm. But it is difficult to establish changes in its level immediately, since the increase is not yet significant. But when a fertilized egg is implanted in the uterine wall (approximately 6–8 days after conception), its quantity increases several times. Because of this, by its level one can judge the onset of pregnancy and how it proceeds.
Therefore, to determine pregnancy in the early stages prescribe a blood test for hCG. 10-14 days after fertilization, when the concentration of human chorionic gonadotropin in the blood reaches a certain level, the hormone enters the urine. From this point on, standard pregnancy tests can be used.
When hCG test can show pregnancy
In order to determine the presence of pregnancy at an early period, an analysis of hCG can be taken from the eighth day after fertilization of the egg. Unfortunately, at this time, the level of hCG in the blood is not yet so high that it can be said with precision about the presence of an embryo.
Often, the results of the analysis can be false-positive or false-negative. Because of this, it is recommended to donate blood on the first or second day of a delay in menstruation and later.
When to donate blood to hCG until delay
At the beginning of the article it was described that the required hormone level for determining pregnancy is reached at 7-8 days after conception. This is about 7 days before the delay of menstruation. But, as mentioned, the concentration of the hormone is still so small that even the most sensitive medical equipment will not be able to give an accurate result. Because of this, if you donated blood before the delay, you should not completely believe the results. It is necessary to repeat the study after 2-3 days and again through the same period of time.. This will give a more truthful result.
- If you are going to take tests, you should not eat 8-12 hours before the scheduled time, that is, blood should be taken in the morning and on an empty stomach. After awakening, it is also not recommended to drink water.
- 24 hours before testing, do not physically load yourself.
- If you have taken hormonal or other drugs, notify your doctor.
HCG Doubling Period
HCG begins to be produced as early as 6-10 days after fertilization of the egg. In the first weeks, the hCG level should double about every 2 days. As the duration of pregnancy increases, its growth rate slows down - when it reaches 1200 mU / ml, hCG doubles every 3–4 days (from 72 to 96 hours), and after 6000 mU / ml it doubles on average every 4 days (96 hours).
PM - the date of the last menstruation.
DPO - days after ovulation.
The concentration of hCG reaches a maximum at 9-11 weeks of gestation, then the level of hCG begins to slowly decrease.
In multiple pregnancies, the content of hCG increases in proportion to the number of fetuses.
Hello, tell me the analysis of hgch showed 33.8 can we talk about pregnancy?
Good evening, please help! I can not figure out the day of conception! Monthly were 06.11.2014 g cycle of 28-29 days. On the 2nd day of December 6, 2014, the hgc delay showed 130.4 m / ml. Could I get pregnant from 11/29/2014 to 04/12/2014? Please help me figure it out! Thanks in advance.
Hello, please tell me, I have a delay of 9 days, from 1 day I did tests every day, all are positive, but I barely see 2 stripes and it does not darken, pregnancy is not 1, there were births, but it always showed a bright second strip, I passed Today, the analysis for hCG 29.57 is a little. I have an ectopic.
Hello. April 17 began the last menstruation, a cycle of 28 days. On the first day of the delay, 33.39 gg / ml, and the fourth day of the delay is 29.99 ng / ml, how should this be understood?
The delay is almost 2 weeks ...
On the 6th day of hCG - 359.7. On the 8th - 485.7 ...
At first there was no one in the stomach. On the 10th day, we saw a pregnancy (NOT ectopic).
Confused little hCG. And the doubling rate is slow. This is normal at all.
Hello, please tell me I gave hCG on the 5th day of the delay. Result5.29 (I'm pregnant)
Hello! Is the delay of 17 days passed on the 17th day of the analysis of hCG 8975 is this a normal indicator?
Good evening, delay 21 days, the cycle is a regular 28 days. There were no delays, especially such long ones. Hgch analysis showed 0.1 ml / l, tests out of 15 (if not more) are all negative, not counting one and that is a very weak second bar. I really want it to be such a long-awaited pregnancy! Or all the same not this time? ((Can somebody tell me something?
Good afternoon, please tell me, I am completely confused and have worn out all my nerves. When the menstruation period had to go, small brown discharge started, 3d day, then pink, so far it has already been 4 days. On the first day I made a test - 2 bright stripes. Why then ran to the ultrasound, they said, only a cyst of the corpus luteum. Went to the gynecologist, says the uterus is pregnant, enlarged. Again, an ultrasound sent, again only a cyst. The geneticist began to speculate that a miscarriage might have happened, and offered to clean up the “remnants”. Naturally refused the next day went to the clinic. She passed the test for HCG - the result is 168. After 2 days, she again took a blood test - the result is HCG 203.
Can such results indicate pregnancy? The delay period is approximately 7 days
Hello. help to decipher. On the 5th day of hCG delay - 1334, in two days the 8th day of 1838. Is this a normal indicator during pregnancy?
Hello. I need your help.
On the 3rd day of the delay, she passed her hgch-284
for the 10th delay hhg-313, progesterone 34.3. a little chest pain and a little pulling the stomach. Is this a pregnancy?
Hello. Later the mesoch was 17.06.15. And 17.07.15 one day the daub was. I had a cycle of 30-36. Day. Test was negative. Ultrasound went 14 day delay. She said that she would take no. 20 day delay. hgn. norm 0-5.0. result.1.20. me in the left hydrosalpingid. what it can be.
Hello. I have 4 day delay. I do not feel any changes, some in the abdominal area, the chest has not increased. 4 tests showed the second not clear strip. The basal temperature is 37.1. Can I be pregnant?
Anastasia, a fuzzy bar is already an indicator. The surest way is to donate blood. Or buy a more sensitive test.
I made a simple frautest — negative (there was not even a hint of the second strip). The next day, I made a digital test to the client (with the definition of a term), showed the coveted “+” and a period of 1-2 weeks. On the same day I donated blood for hCG - 33. This means that the urine content is even lower. The next day I again made a simple frautest — I barely showed the second strip.
tell hgch 27,55 to delay tests negative
Girls, please tell me yesterday was the 4th day of the delay, I passed on hgch on h15.30, did not understand anything, pregnancy 30 is written. Hgch Julia says:
Good day! 9 day delay .. Tests show a positive result. Uzi did the doctor did not see anything obvious on 4 DZ, one tiny point, which may be ... On the same day, I passed HCG - 150.2 mIU / ml. Today I again hCG, I expected to see a growth of at least 2 times, but ... - 181.2 mIU / ml ... This is very sad.
Hello! There was a delay of 3 days made 3 tests, all showed a barely visible second strip, decided to do a digital test showed 1-2 weeks. I went to the ultrasound, I was told signs of pregnancy yet. Donated blood for hCG, the result is 7. The total delay was 5 days and the menstruation began. What does this mean?
Hello, I am 41 years old, my monthly period ceased in May, that is, from March 31 to April 4, it was the last. У меня диагноз : эндометрит , миоматоза в маленьком размере и восполнение матки и месячные не регулярный стало . Врач говорил из за эндометрит . Вот в июле с 11 по 19 дней пролечилась в городе Ташкент.And after the treatment, there wasn’t one month, but in the ultrasound the follicles are there, they said everything is okay, there will soon be periods, and there were no menstruations, but I have some kind of change in my body, nausea, the smell of food, dizziness, and drowsiness. Recently, I passed an analysis on hgc and the result is 17.2 honey / l. Please tell me what it is.
Really looking forward to your reply, please reply
Blood collection process
The process of blood sampling is simple. Experts analyze venous blood, so when you come to the laboratory, you will be asked to sit comfortably and expose any hand. Above the elbow joint, the nurse will put a tourniquet and you will start working with the cam (compress-release). This is necessary so that the veins can be seen better and the blood in the syringe flowed easily.
If the vein is so deep under the skin that the movement of the fist does not help to see it, the nurse will have to take blood from a vein in the wrist area, on the wrist.
Is it necessary to donate blood: the use of sensitive rapid tests
If you are afraid to donate blood or the time when you learn about your situation is not so important (it’s not critical to wait a few weeks), then you can determine if you are pregnant using tests that determine the concentration of the hormone in the urine. Modern women have a choice of several types of tests, differing in accuracy and type of use.
- Simplest - test strips. A special strip is impregnated with antibodies to hCG. It is immersed in a container with morning urine for 10-20 seconds and placed on a flat surface for the reaction. After a few minutes you can find out the result.
- The second type is tablet strip test. This is the same strip as in the first case, only hidden in a special plastic shell with windows. Urine is poured into one window with a pipette, and after a couple of minutes, a result appears in another window.
- The third test is jet. The test is substituted for a stream of urine for 5 seconds and after a couple of minutes the result will be noticeable. The advantage of this test is that not only morning urine is suitable for determining pregnancy.
- More modern version of the jet test - electronic. It is also substituted for the stream, but the result here is not shown in stripes, but in words. Some may also show the duration of pregnancy.
- The latter type of test is very rare. In it, the urine is collected in a special container in which the test strip is embedded. A certain amount of urine gets on it and the result is displayed.
As you can see, the blood test for hCG is very important not only to establish the presence of an embryo, but also to control the course of pregnancy. By the nature of changes in the level of human chorionic gonadotropin, the doctor determines the nature of the pregnancy (normal or ectopic), whether the embryo is dead or there is no threat of abortion. You can also by the level of the hormone to determine the number of fetuses in a woman, the initial stage of development of diabetes in the expectant mother or the appearance of defects in the development of the fetus (Down syndrome, etc.).
How is the hCG content determined?
Determining the presence of hCG and its concentration can be carried out in the blood or in the urine of a pregnant woman. These biological fluids are subject to laboratory research.
There is some evidence that the release of this hormone into the bloodstream is faster by several weeks. Having passed this analysis, you will be able to find out earlier about the fact and duration of pregnancy.
In order to determine the level of hCG in the urine, it is not necessary to contact the laboratory. The pharmacy sells a variety of pregnancy tests. These modern miniature devices can not only confirm the fact of fertilization, but also provide information about the concentration of hCG in the urine of a woman. Each representative of the fair sex knows perfectly well what the two strips on such a test are talking about. The objectivity of this method of verification, according to its manufacturer, is 98-99%. However, in order to accurately ascertain what level of hCG, a woman should trust the laboratory analysis.
When is the best time to donate blood for hCG?
It is known that the concentration of human chorotic gonadotropin begins to grow already in the first days from the moment of fertilization of the egg. According to statistics, in 5% of women the level of hCG increases already on the 8th day after conception.
In the overwhelming majority of pregnant women, the concentration of this hormone begins to grow by the 11th day from the moment of fertilization of the egg. If a woman does not exactly know the date of conception, then blood should be donated for the analysis of hCG 3-4 weeks after the start of the last menstruation. In this case, the expectant mother usually finds a delay of several days.
Quite often, gynecologists recommend a woman to undergo analysis for chorotic gonadotropin twice with a time interval of a couple of days. If the repeated analysis shows an increased level of hCG relative to the first result, then the physician states the growth dynamics and confirms the fact of pregnancy.
Usually within a few days the concentration of gonadotropin increases 1.5-2 times. If the opposite situation is observed, that is, the level of the hormone is consistently low or decreased, then the fertilization of the egg did not occur.
It is very important when passing the analysis to find out the norms adopted in this laboratory. The fact is that in different institutions these figures may differ.
How to prepare for the HCG analysis?
Any special training is not necessary. If a woman takes a drug containing hormones, she must inform the doctor and laboratory technician about this. Some of the medications, especially those with progesterones, can affect the results of the study. It is best to take a blood test in the morning on an empty stomach.
What is the norm of hCG in a non-pregnant woman?
Often, this analysis is given to women, regardless of whether they are pregnant or not. Sometimes the gynecologist recommends checking the level of hCG for suspected certain diseases such as myoma or ovarian cancer. The concentration of this hormone, along with other methods of examination, can directly indicate the presence of the disease.
Normally, the level of hCG in a non-pregnant woman should be 0-5 mU / ml. In women in the period of menopause, due to the restructuring of the body, the content of this hormone reaches 9.5 MU / ml. If the analysis revealed a high level of hCG, then this may be due to the following reasons:
- Reaction to substances in the blood of a woman, similar to hCG.
- This hormone is produced by the patient's pituitary gland.
- A woman takes medication containing hCG.
- The hormone is produced by a tumor of an organ.
In those cases when hCG is elevated and the pregnancy is not detected, the patient undergoes a full diagnosis and receives appropriate treatment.
HCG level during pregnancy
As mentioned earlier, after the implantation of a fertilized egg, the chorion begins to produce hCG. So the embryo is trying to survive in this still hostile world.
The hormonal background of a woman begins to change. The hCG level by day from conception begins to grow quite rapidly. But immediately after conception, fleeing tests to the laboratory is impractical. During this period, as a rule, the result will not show an increase in the concentration of hCG. In order for the laboratory diagnosis to detect pregnancy, it should take at least 7-8 days from the date of fertilization. But gynecologists do not recommend to force events and analyze after delayed menstruation.
Further, determining the level of hCG on days from conception, are guided by the following points:
- The result of up to 5 IU / ml is accepted in international medical practice as negative.
- The indicator of 5-25 IU / ml is considered doubtful, after a few days it is necessary to pass a repeated analysis to observe the dynamics.
- Deviation from the norm is considered a difference of more than 20%. If the result differs from the standard indicators for this period by 50% or more, then we are talking about a pathological phenomenon. If the deviation from the norm is 20%, then the patient is sent for re-delivery of the analysis. In the event that he showed an increase in the rate of difference from standards, then they talk about the development of pathology. If a deviation of 20% was confirmed, or a smaller result was obtained, then this is considered a variant of the norm.
A single laboratory study of the level of chorotic gonadotropin is practiced very rarely. This may be relevant only at the beginning of pregnancy. Basically, a series of periodic analyzes with a specific time interval is assigned. Thus, the dynamics of changes in the level of hCG are observed and pathological conditions such as the threat of interruption, placental insufficiency and others are detected.
How does hCG change during pregnancy days?
In order to assess how the hCG level changes during pregnancy days, you need to carefully consider the table below.
From this table, we can conclude that the level of hCG by pregnancy days changes quite dynamically in the first weeks after ovulation, then the rate slightly decreases and the level reaches stable indicators.
First, it takes 2 days to double the gonadotropin levels. Further, from the 5-6 period, for a two-fold increase in the concentration of hCG, it takes 3 days already. At 7-8 weeks, this figure is 4 days.
When the pregnancy reaches a period of 9-10 seven days of time, the hCG index reaches peak values. By the 16th week, this factor is close to the hormone concentration in the 6-7 period. Thus, the level of hCG in the early stages changes quite dynamically.
After the 20th week of pregnancy, the concentration of hCG does not change so dramatically. Once in 10 seven-day calendar periods, the hormone level rises by about 10%. Only on the eve of birth, the level of hCG slightly increases.
Experts explain such an uneven growth of chorionic gonadotropin to the physiological features of a pregnant woman. The initial growth of hCG indicators is due to the intensive development of the size of the fetus, placenta and hormonal changes in the body of the future mother. During this period, the chorion produces a large amount of gonadotropin to prepare the site for the baby and ensure optimal conditions for its development. After the 10th week, the placenta changes significantly. From this point on, its hormonal function fades away. The placenta is transformed into the main organ of nutrition and respiration in the mother-fetus system. Thanks to this important element, the baby receives all the substances necessary for growth and development, as well as vital oxygen. Therefore, during this period there is a decline in the dynamics of the hCG concentration.
What are the hCG rates by week?
It is very convenient to watch how the level of hCG changes during pregnancy, weekly. At the 3-4th seven-day period, it is 25-156 mU / ml. Already at 4-5 weeks the concentration of the hormone increases: 101-4870 mU / ml. By the 5-6 period, the content of hCG becomes equal to 1110-31 500 mU / ml. At week 6-7, the hormone concentration changes to 2560-82 300 mU / ml. The hCG level after the 7th seven-day period rises to 23,100-151,000 mU / ml. On the 8-9 period the hormone content falls within the range of 27 300 - 233 000 mU / ml. For a period of 9-13 weeks, the indicators of 20 900-291 000 mU / ml are considered normal. By the 13-18 period, the level of hCG is reduced to 6140-103 000 mU / ml. From the 18th to the 23rd week, the hormone concentration is kept at 4720-80 100 mU / ml. Further content of hCG is slightly reduced. From the 23rd to the 41st week, it is kept at the level of 2700-78 100 mU / ml.
How to compare laboratory data with regulations?
After receiving data from laboratory tests, future mothers are in a hurry to find out whether they are in line with the norm. Comparing your results with the above indicators, you should consider one very important fact. The text indicates obstetric weeks, which doctors count off from the date of the beginning of the last menstruation.
The level of hCG during pregnancy at 2 weeks is equal to that of a woman in normal physical condition. Conception occurs only at the end of the second or the beginning of the third seven-day calendar period.
It is necessary to remember the fact that when comparing the obstetric and fetal terms of pregnancy, the first one lags behind the second by two weeks.
If, as a result of the analysis, the result was obtained just above 5 mU / ml, the gynecologist will send a follow-up examination in a few days. Until the level of hCG (from conception) reaches 25 mU / ml, it is considered doubtful and needs to be confirmed. Remember that it is always necessary to compare the results of a study with the specifications of the laboratory where they were carried out. Comparison in the most accurate way can only be done by a doctor.
If the result is below normal
If the result of the analysis of the concentration of human chorionic gonadotropin does not meet the standard and the deviation is more than 20%, then this is a very alarming sign. Initially, the doctor prescribes a re-examination. If at the same time a low level of HCG was confirmed, then this may be a consequence of the following conditions:
- Incorrectly calculated period of pregnancy.
- Regressing pregnancy (missed abortion or fetal death).
- Ectopic pregnancy.
- The development of the embryo with delay.
- The threat of spontaneous miscarriage.
- Prolonged pregnancy (over 40 weeks).
- Placental insufficiency in chronic form.
To make a more accurate diagnosis, the patient undergoes a mandatory ultrasound examination.
The level of hCG in ectopic pregnancy is initially slightly below normal, and then the dynamics drop sharply down. But tubal or ovarian attachment of the embryo with greater accuracy can only be determined by ultrasound. It is very important to identify an ectopic pregnancy in a timely manner, since this condition directly threatens the health and life of a woman. Modern methods of eliminating this condition allow to fully preserve the fertile function. Laparoscopic surgery - seamless and extremely gentle. The rehabilitation period with this method of treatment is minimal.
With missed abortion, fetal death occurs, but for some reason it is not excreted from the body. The level of hCG first remains at a certain level, then begins to decrease. In this case, the doctor observes a thickening of the uterus, since spontaneous abortion does not occur.
Regressing pregnancy can be both in the early stages and in the later period. The causes may be varied, however, a clear dependence of such a state on specific factors has not been identified.
If the indicator is above the norm
Most often, elevated levels of hCG with an overall normal course of pregnancy are not a threatening symptom. It is often a companion of multiple pregnancy or severe toxicosis.
However, if other tests are also significantly different from the norm, then elevated levels of hCG may indicate preeclampsia or diabetes mellitus. This factor is also observed in women taking hormonal drugs.
In addition, the difference in the concentration of human chorionic gonadotropin in a large direction in combination with lowered estriol and ACE (triple unfolded test) may be evidence of the risk of having a child with Down syndrome.
A pregnant woman undergoes two screenings. The first of them is held from 11 to 14 weeks after the moment of conception. The level of hCG in the mother’s blood is measured, and if it is elevated, then we are talking about chromosomal mutations. Based on the data obtained, the doctor calculates the probability of having a child with Down syndrome or other chromosomal diseases. As a rule, in children with trisomy, the level of hCG is elevated. In confirmation of the blood test, an ultrasound scan is performed, and then repeated screening for a period of 16-17 weeks. Sometimes it happens that an elevated level of hCG is detected in an absolutely healthy baby. Then analyze the amniotic fluid for high accuracy of the result.