Angelica tablets for menopause


The climacteric period includes several phases that are accompanied by hormonal disturbances. This provokes the development of a number of unpleasant symptoms that interfere with everyday life. Angelique drug for menopause helps to level hormones, which smooths the flow of menopause. There are contraindications and adverse reactions, so you should consult a doctor before using.

Pharmacological properties

The therapeutic efficacy of the drug due to the unique composition of the drug. The steroid contains hormones estrogen, which compensate for the lack of the same hormones in the body. This allows you to achieve such positive results during menopause, such as:

  1. Decreased sensitivity of the nervous system, improved mood, no abrupt changes.
  2. Normalization of blood pressure, sleep improvement.
  3. Restoration of the vaginal microflora, reduction of itching and irritation, which is caused by a lack of natural lubrication.
  4. The preservation of calcium molecules, which does not allow it to leach out of the bones and develop bone looseness.
  5. Improving the quality of vision.
  6. Normalization of appetite, lack of paroxysmal sensation of hunger.
  7. Reducing the appearance of tides, control sweating.

All these symptoms develop in the female body against the background of an acute estrogen deficiency, which is eliminated with the help of the drug Angelique.

After the tablet enters the digestive tract, its absorption begins. Metabolism occurs in the liver, after which the hormones enter the bloodstream and normalize the condition of the woman.

Drospirenone does not affect glucose tolerance, so it can be prescribed in the presence of diabetes. It is proved that the drug reduces the synthesis of harmful cholesterol, preventing the development of vascular atherosclerosis.

Composition and release form

The German drug is produced in the form of tablets, packaged in plastic packaging. A total of 28 tablets per pack, which is designed exactly for 1 course of admission. Each tablet is numbered for ease of use on a particular day of the cycle.

The structure includes:

  • estradiol - 1 mg,
  • Drospirenone - 2 mg.

Auxiliary substances that contribute to the preservation of the quality of tablets: corn starch, magnesium stearate, iron oxide.

What does Angelica look like during menopause?

Tablets are made in the form of Angelique micro, where all dosages of the active components are reduced to 0.25 mg. It is suitable for those women whose hormone fluctuation is insignificant.

The pills are pink and round. On the one hand there is a risk, on the other there is an inscription “DL”.

Indications for use in menopause

Angelica effectively copes with the normalization of hormonal levels. Indications for its use during menopause are:

  • vaginal dryness and irritation
  • tides
  • excessive sweating
  • the appearance of unwanted hair on the body, not characteristic of the female body,
  • sleep disturbance, when on the background of prolonged insomnia constant drowsiness develops,
  • nervous irritability, frequent mood swings, irritability,
  • heart palpitations, tachycardia, arrhythmias,
  • frequent tension headaches, migraines,
  • lack of sexual desire.

The drug is effective in the presence of muscle and joint pain, which is associated with impaired metabolic processes at the cellular level and increased excitability of the peripheral nervous system.

Angelique helps reduce incontinence. The steroid drug can be used in the post-menopausal period as an adjunct to the main treatment.

The drug is indicated for women prone to bone fractures, which is associated with pathological changes in the bone tissue against the background of a decrease in their density due to lack of estrogen. Angelica has a positive effect on the condition of the skin, making them elastic and resilient. This is possible due to the activation of the natural production of elastin and collagen, which are responsible for the skin condition. Wrinkles become less noticeable, and the skin becomes more taut.

Angelique promotes active weight loss

Drospirenone contained in the drug prevents premature hair loss and the development of alopecia. Reduces the risk of developing skin diseases caused by hormonal disorders.

The steroid prevents the retention of water in the body, so the risk of swelling and hypertension is reduced. He is prescribed to an obese patient. It is proved that the drug contributes to active weight loss and lower blood pressure.

The naturalness of the drug and the maximum similarity of the composition with those hormones that the body produces, makes it safe and harmless with proper intake.

Methods of use and dosage

The drug is consumed 1 tablet daily, preferably in the morning. After the end of the package, if necessary, continue treatment, go to a new pack.

The pill is swallowed without chewing, drinking a small amount of water. There is a need to use pills at the same time, which allows the body to adapt and normalize metabolic processes.

The first tablet from the new pack is taken on the same day when the last tablet from the old pack is used. If the pill was missed in due time, you need to fix it as soon as possible. If there is a gap in the medication for more than 24 hours, vaginal bleeding may develop, requiring correction and observation by a doctor.

Angelique for menopause take 1 tablet per day

There is no need to take 2 or 3 tablets, if there was a pass before. This does not help, but rather provokes the development of a number of adverse reactions.

The drug begins to take only after the doctor has recorded an acute shortage of estrogen in the body, which is possible with the help of blood tests for hormones. External manifestations and symptoms of menopause are not an indication for the appointment of hormone therapy.

Side effects

Often, adverse reactions develop in the case when the drug is taken by a woman without a doctor's appointment or there is an individual intolerance. It may be:

  • development of bleeding,
  • changing the nature of vaginal discharge,
  • pain in the lower abdomen and mammary gland, similar to premenstrual manifestations,
  • nausea and vomiting, discomfort in the stomach, increased gas formation,
  • anxiety increase, sleep disturbance,
  • severe headaches
  • increased fatigue
  • convulsions.

In the presence of individual intolerance, an allergic reaction can develop, which is characterized by the appearance of skin rash, swelling of the mucous membranes, difficulty breathing, increased tearing, rapid heartbeat. Extremely rarely, the drug causes anaphylactic shock and angioedema. This is preceded by high doses of the drug.

In the event of an allergic reaction, the drug is discontinued, providing symptomatic treatment.

Failure to follow the recommended dosage is detrimental to the liver, the cells of which are involved in the process of metabolism. Jaundice may develop.

Drug interactions

With simultaneous long-term use of a steroid with centrally relaxing muscle relaxants, there is a decrease in the therapeutic efficacy of hormone replacement therapy.

The simultaneous use of Angelica and penicillin antibiotics is not recommended due to the reduced effectiveness of both drugs.

Paracetamol and some nonsteroidal anti-inflammatory drugs may increase the bioavailability of estradiol. This increases the concentration of the hormone in the blood, which is fraught with the development of a number of adverse reactions.


The drug is not used in such situations:

  1. When there is vaginal bleeding of unexplained etiology, they first make a diagnosis, and then decide on the need for hormone replacement therapy.
  2. A tumor process in the body (malignant) develops, which, under the influence of an increase in hormones, can be activated and spread to the entire body.
  3. In the body there are hormone-dependent tumors.
  4. The infectious-inflammatory process is progressing, which requires complex treatment.
  5. The presence of tumors in the liver (including cancer), renal pathology, occurring in the acute form.
  6. A history of severe liver disease.
  7. Predisposition to stroke and vascular infarction, atherosclerosis, problems with blood-healthy function and the cardiovascular system.
  8. Pregnancy and lactation.
  9. The presence of genetic diseases.
  10. Individual intolerance to the drug and a tendency to develop an allergic reaction.

With extreme caution, the drug is prescribed to patients after a stroke. With the development of adverse reactions, it is necessary to inform the attending physician about this and select another drug.

It is strictly forbidden to use tablets Angelica without good reason. Appoints steroid agent only doctor, guided by the data of laboratory research. Self-medication can lead to unintended consequences that affect the future health of the woman.


The drug Angelica refers to hormonal drugs, which includes estrogen - estradiol and drospirenonederived from spironolactone. It is intended for hormone replacement therapy (HRT) in postmenopausal women with menopausal disorders (increased sweating, tides, decrease in mood, sleep disturbances, irritability, cardialgia, decrease in libido, involutional changes of the urinary tract) and allows you to avoid regular withdrawal bleeding during phase or cyclic HRT.

Estradiol - provides effective replenishment of the deficit estrogen in the body of a woman after menopause and the relief of autonomic and psycho-emotional symptoms climacteric period. Estradiol effectively prevents bone loss due to deficiency estrogen and manifested by the suppression of osteoclast function and the intensification of the bone destruction process. Prolonged use of HRT after menopause reduces the risk of peripheral bone fractures. HRT has a beneficial effect on the content collagen in the skin, its density and slows the formation of wrinkles.

Drospirenone - It has anti-mineralocorticoid effect, increases the rate of excretion of sodium and water, which prevents the growth of body weight, increased blood pressure, the appearance of edema, other symptoms associated with fluid retention. Drospirenone does not possess any estrogenic, androgenic, glucocorticosteroid activity. The combination with antiandrogenic and anti-mineralocorticoid action provides drospirenone pharmacological profile similar to natural progesterone.

Receiving Angelique reduces the overall level cholesterol and LDL (lipoproteins low density) and concentration triglycerides. Angelique, thanks to antiandrogenic properties drospirenone, affects androgen-dependent diseases (androgenic alopecia, acne, seborrhea).


Estradiol - fully and rapidly absorbed in the digestive tract. Food intake does not affect its bioavailability. During the first pass estradiol through the liver it is actively metabolized to catechol estrogen, estrone, glucuronide conjugateswhich do not have or have mild estrogenic activity. Metabolites are excreted through the intestines and kidneys with a half-life of 24 hours.

Drospirenone - fully absorbed in the digestive tract. Bioavailability of about 76-85%. Food intake does not affect its bioavailability. Most of it is excreted through the intestines and kidneys in the form of metabolites.

Levels estradiol and estrone after the end of the course of taking Angelique to the original values ​​returned within five days.

Angelique, instructions for use (method and dosage)

Angelica tablets taken orally one tablet per day whole, squeezed liquid. Take the drug at the same time of day. If you miss a pill you must take it as soon as possible. If it has been more than a day after the usual taking time, it is not necessary to take an extra pill In cases of missing a few pills, there is a risk of vaginal bleeding. In the case of switching to Angelique from another combination drug, treatment can begin at any time. In the case of a transition from taking the combined drug for cyclic HRT regimen, Angelic should be taken after the end of the current therapeutic cycle.


It is imperative to inform the doctor about the drugs taken by the patient at the present time.

With the joint reception of Angelica with drugs for therapy hepatitis C and HIV clinically significant increases / decreases in concentration may be observed progestin and estrogen.

Abuse of alcoholic beverages while taking Angelique may contribute to an increase in the concentration circulating estradiol.

The admission of Angelique patients on antihypertensive therapy may enhance the hypotensive effect.

Angelic action on the body

In women using Angelique for menopause, there are such improvements:

  • Destructive processes in the bones cease. The probability of injuries, cracks, dislocations decreases. However, for those who already suffer from osteoporosis, the bones are not restored to their original state, so they are shown drugs that restore skeletal tissue.
  • The functions of the ovaries and adrenal glands are improved in patients who are in the premenopausal period. The negative symptoms weaken or are eliminated, the blood circulation is restored, the joints, muscles no longer hurt, sleep is normalized. A woman suffers less from hot flashes, headaches, dizziness, sweating, feelings of heat.
  • If before that there were menstrual bleeding or bleeding, their intensity decreases and pain decreases.
  • The edemas decrease, the heart rhythm normalizes and other manifestations of vascular dystonia weaken.
  • The state of the nervous system improves, the woman becomes calmer, does not get irritated, stops experiencing anxiety, panic, and indulge in depressive thoughts.
  • Libido level is restored, unpleasant sensations in the genital area, caused by burning and dryness, are eliminated. Sexual acts are not accompanied by pain and discomfort. Regeneration of the thinned epithelial layer occurs.
  • Strengthens the muscular layer of the bladder. The problem of incontinence is eliminated, the risk of infectious diseases is reduced.
  • The skin becomes less dry, more elastic, less suffering from rashes. Due to estriol contained in Angelica, deep wrinkles are reduced.
  • Pain or swelling in the chest area is eliminated or weakened.
  • The processes of weight gain and fat accumulation slow down.
  • Normalized blood pressure, cholesterol plaques dissolve and no longer form new ones.
  • The probability of excessive growth of the mucous membrane of the uterus is reduced, the risk of oncology and the formation of benign tumors are reduced.
  • Improves the condition of hair and scalp. Less hair falls out, rashes and seborrhea disappear.

Composition and mechanism of action

Angelique helps with menopause due to 2 active ingredients: 17β-estradiol and drospirenone. The first component is an artificial analogue of estradiol, synthesized by the reproductive organs, the second is a progestin hormone that suppresses ovulation. Estradiol - the strongest and most important of the female sex hormones. It ensures the normal functioning of the female reproductive system, pituitary and hypothalamus. From it depends on the condition of the bone tissue.

Description of the components

With the participation of estradiol, metabolic processes occur, on which the intensity of insulin production and glucose splitting depends. The activity of the cardiovascular system also does not do without this hormone. Thanks to him, the walls of blood vessels remain strong and elastic, and the heart muscle is not exposed to premature wear. In addition, bone density directly depends on the level of estradiol in the body.

Drospirenone is a progesterone-like substance. The main directions of action:

  • antigonadotropic,
  • progestin,
  • antiandrogenic,
  • anti-mineralocortoid.

Drospirenone is responsible for water-salt balance, the state of the mammary glands, as well as for androgenic signs. Thanks to him, a woman ceases to gain weight, her hair falls out less. The combination of estradiol and progesterone-like component gives a balanced effect, in contrast to taking one estrogen. It is important that the use of drugs of this principle protects against cancer, myomas, cystosis, endometriosis.

Excretion from the body

Эстрадиол хорошо всасывается в желудочно-кишечном тракте. In the process of metabolism, estrone sulfate, estriol and estrone are formed - female sex hormones. The active ingredients have a beneficial effect on the functions of the intestines, other organs, as well as on the state of muscle tissue. 28 hours after taking the medicine, bioavailability of 5% is noted. The concentration required for maximum effectiveness is achieved 5 days after the start of treatment. Decay products are derived naturally through the digestive tract and kidneys.

The bioavailability of drospirenone is 70-80% a few hours after taking the medicine. The component breaks down into components and leaves the body naturally. The maximum concentration in the body is noted on the 5th day of treatment.

Auxiliary substances in the composition of the product:

  • povidone,
  • pregelatinized and ordinary corn starch,
  • iron,
  • magnesium,
  • magnesium salt and stearic acid,
  • lactose monohydrate.

Features and indications for use

The use of the drug Angelique in menopause allows you to eliminate the imbalance characteristic of the period of extinction of the functions of the reproductive system.

The onset of menopause is accompanied by a decrease in estrogen production. For this purpose, use hormone-containing agents. Results are achieved if a woman takes medications that contain not only estrogens, but also progesterone-like substances. This feature has Angelic Micro.

Symptoms characteristic of menopause, which helps to eliminate Angelica:

  • fatigue, apathy, weakness,
  • irritability, tearfulness, mood swings,
  • sweating, feeling hot, hot flashes,
  • arrhythmia, pressure drops,
  • increase and decrease in temperature
  • deterioration of the skin, hair and bones,
  • dystrophy of reproductive organs
  • premature termination of the menstrual cycle.

Forms of release and application instructions

Angelica is made in the form of tablets in the shell, yellow on the outside and white on the inside. The pills are round, biconvex. In other forms of release of the drug is not made.

Tablets must be drunk as prescribed by a doctor. Previously the patient is sent for examination to identify diseases that are in the list of contraindications and restrictions. If these are not found, prescribe a treatment regimen. Prior to admission, courses of therapy using other hormonal agents should be completed.

In one package are 28 tablets, they need to drink 1 per day, without chewing or dissolving. The use of Angelica for menopause should be at the same time. Take the swallowed pill with enough water. If, by chance, a woman forgets to take a pill, you need to take it as soon as possible or wait for the next reception. You can not drink more than 1 pill per day, as this may cause bleeding.

Who should not drink the drug Angelica

The use of hormone-containing medication is not allowed if the lady has at least one contraindication. There are also a number of temporary (relative) contraindications to the use of the drug Angelique:

  • senile dementia
  • elevated triglycerides,
  • bleeding of unknown etiology,
  • increased bilirubin level
  • cholestatic jaundice,
  • puffiness.

Angelica is not prescribed to women taking diuretics, medicines to increase blood viscosity and prevent heart failure, drugs containing potassium.

Doctors reviews about Angelique Micro

If we compare Angelique with other medicines containing artificial hormones, we can evaluate its high effectiveness. With the complete elimination of contraindications, improvements were noted in 95% of women undergoing substitution treatment.

Doctors speak differently about HRT. Some believe that the harm caused by unwanted reactions outweighs the benefits. Others consider that each case is individual, and when choosing medical methods one should be guided by data on the patient's health. In general, positive reviews of doctors.

Lack of hormonal drugs is also in the fact that they do not act immediately, and the balance of estrogen and progesterone in the body changes too quickly. There may be a situation where the level of the components of the medicine will be too low or, on the contrary, high. It is necessary to monitor the patient's condition all the time in order to be able to adjust the dosages on time. In practice, this is difficult to implement, so women often complain about the side effects of hormonal drugs.

Characteristics of the drug

Angelica tablets are a hormonal agent that has an anti-menopausal effect. They replenish stocks of female sex hormones, which are depleted during menopause, during hypogonadism or castration.

The drug prevents the manifestation of psychological, emotional, somatic and autonomic disorders during menopause. It normalizes the metabolism of fats and reduces the amount of cholesterol in the blood.

The active ingredients of the agent are estradiol (in the form of hemihydrate) and drospirenone (a progestogen group). The first substance relieves the unpleasant symptoms of menopause, and is also an excellent preventive tool for osteoporosis after menopause.

Drospirenone prevents the appearance of edema, fluid retention and breast pain. The composition of the drug also includes many auxiliary components that enhance the effect of active substances and have a complex effect on women.

Drug Angelica relieves swelling

The principle of the pills

This drug is a combined tool that was created specifically for hormonal treatment during menopause and after it. Angelica is also prescribed for:

  • reduced physical activity
  • failure of the ovaries,
  • castration.

The drug helps to cope with these symptoms:

  • excessive sweating
  • tides
  • frequent mood changes
  • trouble sleeping
  • irritability,
  • problems with the genitourinary system and others.

Due to the complex action of the drug, the woman feels improvement, her self-confidence increases, it is easier for her to survive this difficult period.

Angelica is also prescribed to prevent the occurrence of frequent bone fractures in the post-menopausal period. The pills will not be able to fully restore the bone mass of a woman, but they reduce her loss at this stage.

Due to the broad spectrum of hormones, Angelica saves from the manifestations of acne, seborrhea, male-type hair loss and other pathologies that occur when there is excess androgen (male sex hormones).

The use of the drug will remove the main symptoms of menopause

How to drink the drug Angelica

All hormonal agents that are used to alleviate the symptoms of menopause have a special regimen. Manufacturers produce the drug Angelica in blisters of 28 pieces. This package is calculated on the 28-day menstrual cycle.

A woman should take 1 tablet per day. Reception does not differ from reception of other medicines. The tablet should not be chewed. It is enough to drink a small amount of water (it can be boiled). Taking the drug does not depend on the use of food.

Doctors advise to drink Angelik around the same time of day. This is not important, but such a schedule will help the woman's body to get used to the drug faster and improve the work of the systems and organs.

The manufacturers made sure that the patient did not forget to take another pill: in the blister, each tablet corresponds to the day of the week. But if you forgot to take the medicine, you need to quickly do it. Sometimes a woman remembers a medicine in a day or more. In such cases, you need to skip the not drunk pill and continue taking it.

When a patient does not take a few pills, she may develop bleeding. In such cases, you should see a doctor: complications are rare, but abruptly stop taking this type of drugs can not.

After successfully taking 28 tablets, you should start drinking the next pack of Angelica without a break. If the patient begins to drink drugs with estrogen or has taken other drugs with a similar continuous action, then you can begin treatment with Angelica immediately.

Those women whose therapy occurred under the action of a cyclic drug should wait until the end of the monthly bleeding. Then you can continue the treatment with Angelica tablets.

Angelica should be taken cyclically.

Overdose and side effects

If the daily dose of pills exceeds the normal rate several times, then this will not lead to serious side effects. Laboratory studies have shown that the human body is able to transfer high doses of hormones that are part of the tablets. The main symptoms of overdose are:

  • nausea and vomiting,
  • vaginal hemorrhage.

In such cases, you need to consult a doctor and indicate what dose was taken. Consequences are treated by way of eliminating the symptoms.

Angelica tablets are a hormonal drug. Their composition affects many organs and systems of a woman. Any reaction is a normal response of the body to therapeutic action.

During the adaptation period, which for all women lasts individually, bleeding from the genital tract may occur. Thus, the reproductive system responds to the drug. If after a while this symptom does not disappear, then you need to notify the treating gynecologist.

A woman's reproductive system can respond to hormone therapy with breast pain, exacerbation or relapse of diseases of these organs. Often in the gland there are new formations (malignant or benign), which require a review of the course of therapy.

While taking Angelica tablets with the pelvic organs also changes occur. Some women complained about the appearance of uterine formations (fibroids), cervix and other parts of the genital organs.

Due to the oral route, it affects the stomach and intestines. Patients often complained of abdominal pain, bloating, nausea. These conditions can lead to loss of appetite, which results in weight loss. On some women, the pills acted differently: there was an increase in weight due to increased appetite.

The physician should also warn the patient about possible disturbances in the nervous system. They are manifested by frequent headaches, mental disorders (depression, rapid mood swings, nervousness) and other conditions.

It is not known how the woman's body will react to the pills: everything is very individual. The list of pathological conditions due to the start of taking Angelica during menopause can be supplemented with such deviations:

  • decreased libido
  • frequent dizziness,
  • problems with blood vessels (thrombosis, varicose veins and others),
  • migraine,
  • pathology of the skin and hair,
  • development of cancerous tumors of the reproductive system,
  • ringing in the ear (ears) and so on.

The manifestation of any new symptom while taking a hormonal drug should be a reason for an additional appeal to the gynecologist. He should reconsider the possibility of further therapy with this tool.

Before prescribing the drug, the doctor tells the patient about its side effects.

When not to take pills

Angelica drug is not used as a contraceptive. It is also forbidden to take pregnant and lactating women. If the suspicion of pregnancy is confirmed, then the pill is prohibited.

These are the main contraindications to the use of tablets. But doctors also do not prescribe them if the patient has:

  1. Bleeding from the genital tract of unknown etiology.
  2. Oncological disease of the breast and the period after it.
  3. Suspected or presence of a hormone-dependent tumor (malignant).
  4. Serious violations of the liver and kidneys.
  5. The period after a heart attack or stroke.
  6. The appearance of blood clots in the vessels.
  7. Allergy to the constituent parts of the drug and other pathological conditions.

Patients with high blood pressure, endometriosis, uterine myoma, epilepsy, bronchial asthma, or diabetes mellitus are taken under the strict supervision of a physician.

Breast Oncology - a contraindication for taking the drug