Depo-Provera injection as a contraceptive method


I am almost 38 years old and almost 3, 5 years old, I have no periods. Were treated with Propox injections, as at 34, when a polyp was removed in the uterus, signs of adenocarcinoma were found, according to analysis, such as dysplasia. But anyway, the dose of these injections was given to a horse — 4 months, 150 μg each — only 18 injections. the doctor promised that within a year I would recover (cycle), but he was gone for more than 3 years. although for a long time with breaks I drank Femoston (as a replacement. therapy), with breaks. Who has undergone such treatment, how to recover, write, I will be grateful. I moved from Odessa to Russia, my salary is a penny, there is no possibility of getting to the best doctors of Moscow. Not only did I almost say goodbye to the idea of ​​having children, although I want to get out of the artificially induced menopause, then there is no menstruation. I'm scared((

Aksenova Anna Mikhailovna

Psychologist, Candidate in group analytics. Specialist from the website

Do you have an ultrasound? Tests for hormones FSH, estradiol handed over?

Depo Provera. “What kind of" smart doctor did you appoint?! I put it on the advice of the same "smart" doctor for protection in my youth and menstruation I didn’t have for a long time. Then I heard that she was very unhealthy

Depo Provera. “What kind of" smart doctor did you appoint?! I put it on the advice of the same "smart" doctor for protection in my youth and menstruation I didn’t have for a long time. Then I heard that she was very unhealthy

Did I really have a choice? I generally wanted to cut a uterus and ovaries in Chisinau, and this is 34 years old! I refused and went to Odessa. they confirmed the diagnosis, they said it was almost dysplasia, and it could be treated with hormones. after treatment, hysteroscopy was done again, everything was clean. It turns out one cured, but another crippled. But at that time, the doctor (the best in Odessa by the way) promised me that everything would recover in a year. But a year has passed, the second, the third, the fourth has already gone - I'm really scared. It is terrible not to get out of menopause, do not have a child .. For me it is very important. Up to 42 years, as the doctor said there is a time. But I am already almost 38, and the hope of an independent pregnancy is melting. Yes, I took all the tests - estrogen, progesterone, prolactin (it was increased - Doxinex saw), testosterone, FSH, ultrasound, thyroid hormones. all vobschem it showed normal, only prolactin overestimated. on the ultrasound a thin endometrium, and does not even respond to Femoston, 3-4 mm, the largest was 6. I quit drinking Femoston, the ovaries are reduced, the size of the uterus too, as if everything is still there.

Estradiol handed over the reception femoston? Then it's not yours, and the pill hormone showed you an analysis. And if during a break, according to your data, estradiol should be lowered, once the endometrium is thin. It is strange that everything is normal. On the ultrasound ovaries looked? How many follicles?

Of course she gave before taking the therapy, estradiol was really lowered. We looked at the ultrasound all, all the organs of the small pelvis. Follicles are few. And for some reason, now, after 2 years, she went back to the ultrasound, to another doctor. She knows my diagnosis, I told her about the follicles, asked to see how the situation is now. She says a normal amount. I asked her to look especially carefully, saying that it depends on the bud. pregnancy. Says, normally you have follicles. I understand that they are not restored, who was mistaken I do not know. You will need to go to another doctor, with a good ultrasound machine.

Related topics

How to recover now? Did someone go through this treatment? Femoston 1/2 does not help, the endometrium does not respond. The doctor said that the receptors were dulled, so there is no reaction.

I am almost 38 years old and almost 3, 5 years old, I have no periods. Were treated with Propox injections, as at 34, when a polyp was removed in the uterus, signs of adenocarcinoma were found, according to analysis, such as dysplasia. But anyway, the dose of these injections was given to a horse — 4 months, 150 μg each — only 18 injections. the doctor promised that within a year I would recover (cycle), but he was gone for more than 3 years. although for a long time with breaks I drank Femoston (as a replacement. therapy), with breaks. Who has undergone such treatment, how to recover, write, I will be grateful. I moved from Odessa to Russia, my salary is a penny, there is no possibility of getting to the best doctors of Moscow. Not only did I almost say goodbye to the idea of ​​having children, although I want to get out of the artificially induced menopause, then there is no menstruation. I'm scared((

Guest, how are you?
I have the same situation after depo-provery. There was endometrial cancer. After PD everything is clean, but a year has passed since the last injection and everything is deaf in monthly periods. Small follicles have 5-8mm, but the endometrium is at around 5-6 mm. Femoston 1/10 did not help, now began 2/10. I’m still afraid to prescribe more hormones with such a history.

The problem is that the hormones I can not lose weight at all. Sport - by myself, I shake the press so that there is a good circulation of blood in the pelvis and abdomen. I even use Sytin's mood - I downloaded a mood for healthy uterus and ovaries on YouTube. I listen and visualize. In general, in May 18, it will be exactly 4 years - like me without periods, for me this is the limit. If not recovered, I will deal with this issue tightly. Generally on the forum at Sekirina discuss this topic a lot. Those who did even 1-2 injections for a long time recovered. In the manual it is written that even a one-time injection can turn off the months for a period of 9 to 30 months. And I received a horse dose of 18 injections, of course, the ovaries turned off and still slow down. Who was treated like me, almost all recovered 3-4 years. One girl wrote that for 6 years there are no periods. But it is necessary to recover, because to go to menopause so early, it is very harmful for the body. Olive, a year - in my opinion, little time has passed for you, at least after 2. And yet, I am also against tough stimulation, I'm afraid. Although the doctor suggested, I immediately told him that I didn’t want it, so that later I could back up with something else, he agreed.

Yes, Femoston quit taking so far, what is the use of it if I get fat from it, and the endometrium is still not growing, there are no menses. It may be wrong, but for the time being I will be losing weight and what I wrote above. After six months, the doctor may write me another treatment regimen. I will fight to recover.

The problem is that the hormones I can not lose weight at all. Sport - by myself, I shake the press so that there is a good circulation of blood in the pelvis and abdomen. I even use Sytin's mood - I downloaded a mood for healthy uterus and ovaries on YouTube. I listen and visualize. In general, in May 18, it will be exactly 4 years - like me without periods, for me this is the limit. If not recovered, I will deal with this issue tightly. Generally on the forum at Sekirina discuss this topic a lot. Those who did even 1-2 injections for a long time recovered. In the manual it is written that even a one-time injection can turn off the months for a period of 9 to 30 months. And I received a horse dose of 18 injections, of course, the ovaries turned off and still slow down. Who was treated like me, almost all recovered 3-4 years. One girl wrote that for 6 years there are no periods. But it is necessary to recover, because to go to menopause so early, it is very harmful for the body. Olive, a year - in my opinion, little time has passed for you, at least after 2. And yet, I am also against tough stimulation, I'm afraid. Although the doctor suggested, I immediately told him that I didn’t want it, so that later I could back up with something else, he agreed.

How does Depo Provera prevent pregnancy?

The drug contains a synthetic form of the hormone progesterone - progestin - which has a long-lasting effect. Progestin inhibits your ovulation, so the ovaries do not release eggs.

Moreover, if you still have ovulation (which is unlikely), progestin thickens your cervical mucus, making it an insurmountable barrier to sperm penetration. Thus, sperm cells cannot penetrate the cervix, fall into the fallopian tubes and meet with the egg to fertilize it. Progestin also makes the inner layer of the uterine lining very thin, which prevents the egg from implanting into the uterus.

Efficiency of injection contraception

«Depo Provera»It has established itself as a drug with 99.7% efficacy with proper and regular use. This means that if 1,000 women receive injections (once every three months) within a year, then only 3 of them will become pregnant. In most cases, unwanted pregnancy occurs in women who missed (most often - forgot) to make another injection.

Side Effects of Depo Provera Injection

The most common side effects of injectable contraception are unpredictable (i.e. irregular) menstrual periods and vaginal bleeding (or bleeding) between the menses.

Three months after the first injection, these side effects begin to pass, and over time, most women stop their menstruation altogether. By the end of the first year, 50% of the women who received injections stopped the menstrual bleeding, and 2/3 of the women lost their period after two years. But in some women (about 1%) after the injection, on the contrary, the periods become longer and harder, and do not stop even after two years.

During the first year of women, there is a slight increase in weight, about 2.5 - 3.5 kg. Some women notice that their appetite increases greatly. Therefore, if you decide to use this method of contraception, you should review your diet and begin to exercise.

Progestin can lead to loss of calcium stored in your bones, which leads to a decrease in bone density. The longer you use progestin, the higher the risk. For this reason, doctors do not recommend using this method for more than two years in a row. The loss of calcium in this case is a reversible process, so after stopping the use of progestin-containing drugs your bones begin to become saturated with calcium again.

Headaches are another side effect of using "Depo ProveraFor some women. Less common side effects are:

  • change in sex drive,
  • vaginal dryness
  • hair loss on the head,
  • hair growth on the face and body,
  • acne (acne) on the face,
  • dizziness,
  • nausea,
  • skin rash,
  • breast tenderness or tenderness.

Some women notice an increase in depression or the emergence of unexplained anxiety after the introduction of injectable contraceptive drugs.

"Depo-Provera" during breastfeeding

You can use the injection "Depo Provera", Like other progestin-containing contraceptives, immediately after birth. Progestin, of course, in small quantities into breast milk, but it does not affect the child, nor the quantity and quality of milk (unlike estrogen, which suppresses lactation).

When can I get pregnant again after canceling Depo Provera?

Pregnancy rarely occurs earlier than six to twelve months after the last dose of the drug. Therefore, if you want to try to get pregnant next year, then you better choose another method of contraception, which is quickly reversible.

As a rule, ovulation in a woman resumes three to six months after the last injection, but conceiving a child can take another few months. In 20% of women, pregnancy occurs in six to seven months, in 50% in seven to nine months, and in 30% in one to two years.

You can learn about the resumption of ovulation when you have a regular monthly cycle again. Before you try to get pregnant, be sure to go to the appointment with the gynecologist, and start taking folic acid or multivitamins for pregnant women.

Should I use backup methods of contraception after the first injection of Depo-Provera?

If you were given an injection during the first three weeks after delivery, or within seven days after the start of the cycle, then you do not need to use backup methods of contraception. If you received the injection at any other time, you will need to use backup contraception (for example, condoms) for at least the first week.

If your doctor thinks that you have lactational amenorrhea - that is, you only breastfeed your baby, less than six months have passed after giving birth, and your menstruation has not yet resumed - then you will also not need backup contraception.

What to do if you missed the next injection?

If more than 14 weeks have passed since the last injection, then you need to either abstain from sex, or use a backup method of contraception, until you make a new injection, and for seven days after that.

If you missed the injection and had unprotected sexual intercourse, then you should better use emergency contraception to prevent pregnancy! Such drugs are effective for the first 72 - 120 hours (that is, from three to five days) after unprotected sex, but the sooner you take them, the higher their effectiveness.

You can buy emergency contraceptive pills (Eskapel and Postinor) in almost every pharmacy without a prescription.

When do I need to see a doctor urgently?

Serious problems after the injection of Depo-Provera rarely occur, but if any of the following symptoms occur, immediately consult a doctor:

  • severe headaches or worsening,
  • pain or tenderness in the lower peritoneum, in the abdomen or in the pelvis,
  • unusually heavy vaginal bleeding
  • itching, bleeding, severe pain or suppuration at the injection site,
  • jaundice (yellowing of the skin or eyes),
  • depression.

Also, be sure to consult your doctor if you suspect that you are pregnant, if you have found a tumor in your chest, if you have vaginal discharge characteristic of diseases of the genital tract (STD), or if you are simply concerned about the reaction of your body to the injection.Depo Provera».

Pregnancy after birth control pills

Oral contraceptives are a common, reliable and safe way to protect against unwanted pregnancy. The drugs are easy to use, effective and affordable. To date, hormonal contraceptives are available in a very large assortment.

But you should not choose them on the advice of girlfriends. A specific contraceptive may be prescribed by a doctor based on the health status of the woman. The gynecologist will perform simple measurements that can guarantee the safety of the drug: woman's weight, height, blood pressure. A number of additional tests (blood, urine, vaginal smears) are needed to rule out any disease.

In the process of taking hormonal drugs you need to carefully monitor the blood sugar level, prothrombin, regularly visit the gynecologist even with satisfactory health and no complaints.

Features and effects of birth control pills

The basis of hormonal drugs is the use of synthetic analogues of natural ovarian hormones. Among the contraceptive pills the most popular ones are combined contraceptives, since their level of reliability, tolerability, reversibility of action and acceptable cost significantly distinguish them from other means.

Such drugs include two types of female sex hormones: gestagens and estrogens. It is thanks to them that ovulation and implantation are blocked, as well as the movement of sperm cells, the work of the corpus luteum, the latter is a replacement for the released egg and ensures the normal formation of the ovum.

After the end of the medication, the release of the eggs from the ovary, which occurs in the middle of the menstrual cycle (ovulation), is getting better and most women (about 90%) can survive pregnancy after birth control pills within two years.

It is possible to conceive a child after the end of taking birth control pills with the full restoration of ovulation (as written in most instructions for such drugs). This period begins two weeks after discontinuation of medication.

Sometimes hormones and ovulation get better along with the abolition of pills. In such a situation, the quick conception is provided by the ovaries, which, after a long forced rest, function intensively. Some women need to wait for months to establish an ovulation, not every body recovers quickly.

Pregnancy planning after the abolition of birth control pills

Before completing the process of taking contraceptives, in order to do this as correctly as possible, it is better to consult with the doctor who prescribed the contraceptive. If necessary, be examined and tested.

After discontinuation of the drug, you must carefully monitor the menstrual cycle and keep a calendar. This will facilitate the most accurate calculation of suitable days for conception and the duration of pregnancy.

Be sure to balance your diet, as long-term use of hormonal contraceptives changes the vitamin-mineral balance in the female body. Sometimes there is a decrease in folic acid, the level of vitamin C, certain trace elements.While vitamin A is absorbed in excess amounts, it can adversely affect the development of the child. In this situation, the doctor will help, who will select the optimal vitamin-mineral complex.

How to stop taking medications

Many women are confident that you can stop taking the pills at any time, not necessarily finish the packaging until the end. So does the majority, not knowing that in fact they risk their own health.

Experts recommend to finish all the packaging. After all, discontinuation of contraceptive in the middle of the cycle can cause hormonal disorders and heavy bleeding. Starting attempts to get pregnant after birth control pills can be immediately after the abolition of contraceptives. But It should be noted that much depends on the duration and frequency of use of this type of contraception. At the end of a 3-6 month intake, the ability to conceive a woman generally does not decrease, even the opposite increases the chance of becoming pregnant in the first three menstrual cycles.

But when the intake of contraceptives lasted continuously for several years, it can lead to the suppression of the reproductive function of the female body, then it will take a full year for full recovery. The greater the age of the woman, the longer this period: in 20 years - a few months, in 30 - a year or more, and after 35 - years.

Therefore, gynecologists recommend doing after a year of taking contraceptives 3-month breaks. Otherwise, you can get pregnant only by in vitro fertilization.

Long-term use of these drugs does not adversely affect the course of pregnancy, development and health of the unborn child. Even the conception that occurred during contraception using oral contraceptives does not affect the successful outcome of pregnancy. Thousands of healthy children are confirmation of this statement.

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Conception after birth control pills

There are many different hormonal contraceptive pills. Oral contraceptives are a very common way to protect against unwanted pregnancy, as the pills are available, easy to use and effective. Depo Provera is another type of hormonal contraception. The procedure is administered as an injection every three months. The first injection is recommended to do in the first five days of the cycle. Women often use Depo Provera because this procedure is less time consuming and easier to use than birth control pills. Although this may be easier in many ways, it is more difficult to get pregnant after Depo-Provera. Another type of contraception is Mirena Navy (spiral). This is a small plastic device that is inserted by the doctor through the cervix into the uterus. IUD can be used to prevent pregnancy to five years.

If you decide to get pregnant and stop using contraceptive drugs, then you may have questions. When to stop taking pills or other drugs? How long to wait for conception after the abolition of contraceptive drugs? Answers to these questions will depend on many factors, for example, what type of birth control you used and whether you had a normal menstrual cycle before using contraceptive drugs.

Frequently asked questions after the abolition of contraceptive drugs:

Pregnancy after Depo-Provera.

If you used Depo Provera, it may take longer to restore the cycle. Depo Provera is designed for long term birth control. Depo Provera is a synthetic hormone similar to progesterone. It inhibits ovulation, and also dilutes the surface of the uterus to prevent implantation. The level of synthetic hormone when taking Depo increases within three weeks and reaches a peak level. After cancellation, the level of the hormone begins to decrease. It can last up to 200 days until the hormone completely leaves your blood. The menstrual cycle can be restored about a year after the abolition of Depo-Provera, and conception may not occur until two years.

Pregnancy after using Mirena Navy (spiral).

Mirena releases a synthetic hormone into the uterus, similar to progesterone. The cervix becomes thick, which prevents the spermatozoid from reaching the egg cell. The helix can prevent ovulation, but more often it simply blocks the passage of the spermotozoid to the egg cell. After you have removed the Navy, ovulation should be restored fairly quickly. Once your cycle is restored, you have every chance of becoming pregnant.

How long to wait to start trying to conceive a child?

You should know that it is perfectly safe to start trying to conceive immediately after the abolition of contraceptive drugs. But you can wait for the recovery cycle and then start trying to conceive a baby. If you do not wait for the recovery cycle, it will not be a risk for pregnancy, but doctors recommend waiting for more confidence. In addition, if you have a regular cycle, then it is much easier to predict ovulation.

What if your cycle does not return?

If you have not used Depo-Provera, your cycle should return within two to three months. And after Depo Provera it takes more time to restore the cycle. If you start trying to get pregnant before the start of your menstrual cycle, then you may get confused and think, why do you have no menstruation? Because your cycle is delayed due to cancellation of contraceptive drugs, or perhaps you are already pregnant? Unfortunately, after you stop taking contraceptive drugs, time is needed to restore your body. You may be in uncertainty, if you did not wait for the restoration of the cycle and started trying to conceive. Since you will wait for ovulation and can confuse the signs of ovulation with signs of pregnancy. This may confuse you even more, as you may think that you are pregnant, but not be so. If your cycle does not return, the easiest way is to do a pregnancy test every few weeks until the cycle recovers. If your menstrual cycle does not return within six months, you should consult a doctor.

Pregnancy and birth control pills

When can I get pregnant after taking birth control pills? This question is quite relevant, since so many modern girls use hormone pills as a contraceptive. But although it sounds so scary for many - “hormonal”, they do not bring much harm to the body if taken by a healthy woman. And the possible negative consequences of their reception occur much less frequently than from an artificial termination of pregnancy. To date, it is combined oral contraceptives that are considered the most effective protection against unwanted pregnancy. If you follow all the nuances of the instructions, then you can easily take them for several years in a row, even without a break. But how does the short-term and long-term use of birth control pills affect subsequent pregnancy? Does such contraception cause infertility?

No, all these are myths. By the way, even the recommendation to wait with pregnancy for 2-3 cycles after taking the pills is not justified. You can get pregnant immediately after the abolition of birth control pills, it is not dangerous. In this case, conception occurs quickly, since after a forced rest the ovaries begin to ovulate intensively. To get pregnant "to cancel oral contraceptives" is recommended also by experts on some "innocuous" types of infertility.

And yet, is it possible to get pregnant by taking birth control pills and what to do if this happens? In fact, such cases in the world medical practice are very, very rare and are associated not with “not high-quality” drugs or their “wrong” (this does not happen) selection, but with violation of the admission rules. For example, the effectiveness of birth control pills is reduced when they are irregularly taken (if the time intervals between taking the pills are more than 36 hours), while taking them with most antibiotics and even with traditional medicine, namely, with hunters, with diarrhea or vomiting, less than 4 hours after ingestion (in such cases, an additional pill should be taken, since it is highly likely that the former did not fully digest). Therefore, very carefully read the instructions and keep it always at hand.

If, nevertheless, pregnancy while taking birth control pills has come, then it is not necessary to interrupt her if the child is desired. Pills taken in the early periods of pregnancy will not cause any harm to the fetus. If you take oral contraceptives and after a 7-day break in the reception you did not have menstrual bleeding, take a pregnancy test, and even better - donate blood for hCG. Before the results are obtained, do not start drinking new packaging. Another interesting point - when taking low-dose drugs, periods may be completely absent or be very scarce. And this is also the norm.

Birth control pills: effects on future pregnancy

When taking oral contraceptives, many women have anxiety about the effect of these drugs on the future pregnancy and, accordingly, on the development of the unborn child. If we approach the issue from this point of view, then it should be noted that, of course, a certain risk is present, and the possible consequences directly depend on the duration and frequency of pills. Moreover, it should be borne in mind that taking birth control pills affects each woman differently, from which one woman can take them for several years, and then not have any problems with conceiving and carrying a child, and another woman may have difficulties after several months of taking contraceptives. drugs.

“Pregnancy is on cancellation”: rebraund effect

In some cases, birth control pills are prescribed to patients by doctors to get the opposite effect — that is, get pregnant. Yes, it is precisely for the purpose of conceiving a child. The fact is that after taking oral contraceptives ceases, the so-called rebound effect may occur. It is understood that over the next three cycles after stopping the pill, the chances of conception significantly increase. In this regard, some doctors specifically prescribe oral contraceptives for a short period of time (2-4 months) to their patients in order to provoke a “pregnancy with cancellation”. The fact is that during the intake of birth control pills, ovarian function is inhibited, which stops the onset of ovulation. This “expectant” state of the ovaries continues for quite a long time, and as soon as the oral contraceptives are stopped, the ovaries begin to “catch up”, that is, to work with great diligence. In this regard, the tactic of taking birth control pills is widely used by gynecologists in the treatment of some forms of infertility. Due to the enhanced work of the ovaries, pregnancy in many cases occurs in the first month after the abolition of the pills. But it should be noted that in some forms of infertility this method is ineffective, so sometimes a second course of hormonal drugs is prescribed according to the scheme: three months they take contraceptives, two months they don’t, then repeat the medication again.

The likelihood of pregnancy after taking birth control pills

When oral contraceptives are used to prevent unwanted pregnancy, it is assumed that the course of taking the drugs will be much longer than a few months. Some women are concerned about the effect of the duration of the course of birth control pills on the probability of becoming pregnant after their cancellation. Definitely answer this question is almost impossible. But some gynecologists believe that the long-term, namely the long-term use of oral contraceptives without interruptions can lead to the fact that the body gets used to the constant flow of hormones that suppress ovarian function, due to which the production of their own hormones can be reduced. Based on this, many doctors believe that semi-annual oral contraceptive use will not lead to any serious disruption of the female organs, but a long two-year or more medication significantly increases the risk of “inhibition” of ovarian hormone production, after which problems may occur with further conception. As a rule, today gynecologists advise to spend a three-month break in taking birth control pills after each year of their use. But, unfortunately, many women prescribe hormonal drugs themselves, unaware of the possible consequences, and do not adhere to the tactics of intermittent use. And only in the future, they strongly regret such a rashness, when it becomes necessary to combat infertility.

What kind of drug

The main active ingredient of depo-prover is medroxyprogesterone acetate, it is similar in its effect on the gestagens - hormones of the second phase in women. Various forms of medication and doses are produced, but injections are most often prescribed, they are most convenient from the point of view of the time interval of administration and the effect exerted.

The therapeutic effect of depo-prover is due to the following effects:

  • It inhibits the production of gonadotropic hormones of the pituitary LH and FSH, which adversely affects the growth of follicles, resulting in complete suppression of ovulation. As a result, many hormone-dependent diseases do not progress, and even their manifestation decreases gradually.
  • De-provera has a negative effect on the growth of the endometrium, which is used in the treatment of pathology of the uterine cavity.
  • Increases the properties of cervical mucus, which additionally forms a kind of barrier to the penetration of sperm.

Some undesirable effects of the drug are due to its pyrogenic effect, i.e. when taken, the body temperature rises, but it does not reach critical values. Depo-Provera also has mineralocorticoid activity. This can cause the development of Itsenko-Cushing syndrome with prolonged use.

A special feature of the drug is that it penetrates the blood-brain barrier, i.e. in the structure of the brain, as well as through the placenta (if taken suddenly during pregnancy, although it is contraindicated) and in breast milk. This should be considered when applying it.

We recommend to read the article on the monthly while taking birth control pills. From it you will learn about daily and emergency contraception, its effect on menstruation, the features of the use of certain drugs.

Indications for appointment

Depo-Provera is used in various fields of medicine. So, the indications for its use are as follows:

  • In oncology practice for breast cancer, endometrium, prostate, kidney and some other conditions.
  • In gynecology for the treatment of endometriosis, uterine fibroids, chronic endometritis, endometrial hyperplasia, polyposis.
  • It is also possible to use depo-provera for contraception in women who do not plan pregnancy during the next year or two.
  • The drug is indicated for the correction of menopausal disorders in women, such as hot flashes, hot flashes, sweating, and the like.

Look at the video about contraception:


The drug can not be used for allergic reactions to this and other similar means. Also contraindications are the following situations:

  • During pregnancy and breastfeeding, as depo-provera penetrates through all barriers and can negatively affect the development and growth of the baby.
  • Given that the drug is metabolized and excreted through the kidneys and liver, it should be used with extreme caution when the organs of these organs are disrupted.
  • For ever established epilepsy, migraine, bronchial asthma, serious cardiovascular disorders, the drug should be used only in extreme cases.
  • If the agent is prescribed for contraceptive purposes, as well as for the treatment of non-cancerous tumors, it is necessary to exclude possible hormone-dependent tumors.
  • Also, in the presence of diabetes, the drug can affect the degree of effectiveness of essential drugs.
  • Since depo-provera can contribute to the development of depression, it should not be used in severe cases of this disease.
  • In case of violation of blood coagulation abilities, as the drug increases the likelihood of blood clots.

Reception features

Depo-Provera can be used in the form of tablets, spray or intramuscular injections. The latter form has found the greatest use in gynecology.

Doses and regimens in oncological practice are distinguished by a higher dosage and smaller intervals between doses. Это необходимо для того, чтобы создать подавляющую злокачественный рост концентрацию препарата в крови.

При применении в гинекологии используются следующие варианты:

  • с целью контрацепции назначается 150 мг препарата на три месяца,
  • для лечения эндометриоза дозу увеличивают до 50 мг каждую неделю или 150 раз в две,
  • during the period of formation of menopause or already during it, 150 mg of the drug is used for 12 months, if necessary, the course is repeated.

The main ones include the following:

  • Anovulation and prolonged suppression of the function of the hypothalamus and pituitary. Therefore, the monthly after depot prover may still be absent for quite a long time.
  • Change in body weight. Many women claim that they have significantly gained weight, but there are no reliable statistics on this. In most cases, weight gain occurs due to natural aging processes, as well as a change in lifestyle.
  • Mental disorders are sometimes observed, especially in patients predisposed to it. In addition to depression, decreased libido, irritability and some other symptoms, there may even be a decrease in attention and concentration, migraines, etc.
  • Acne, hirsutism, hair loss and others often appear.
  • Also, some disorders can be observed in the cardiovascular, digestive, urinary, endocrine and immune systems.

Monthly after the drug

Quite often, you may encounter a situation when there is no menstruation after the injection of depo-prover, and a woman may not be quite ready for this. Such situations may be due to the following:

  • If you use large doses of the drug, which is typical for the treatment of cancer. In this case, it takes a long time to restore its own products of FSH and LH.
  • With increased sensitivity of the pituitary and hypothalamus to the drug. Monthly can not be restored for a long time even after one injection.
  • If the liver and kidneys are impaired, when the depo-provera is slowly removed, then it can maintain its activity for more than a year. This is observed when it accumulates in the adipose tissue of a woman, whence it then enters gradually into the blood.
  • If the period of taking the drug coincided with the onset of menopause in a woman, including an early one. Or he can even speed her approach somewhat. In this case, after taking the medication, menstruation cannot be restored only if artificial hormones are created using HRT (hormone replacement therapy).

The following menstrual irregularities are permissible while receiving depo-provera:

  • periodic spotting for several months and the lack of normal critical days,
  • breakthrough bleeding,
  • absence of periods up to 6 months or more, in this case, it is necessary to exclude pregnancy.

Chances of conceiving

Young women are often interested in the question of how their periods go after depot provers and when they can plan a pregnancy. In most cases, follicle maturation and ovulation begin from the second to third month after discontinuation of the drug. But it is possible that it will take more time.

If a woman is strongly interested in pregnancy, hormonal correction with the help of estrogens and gestagens is possible at the discretion of the doctor. Individual schemes in each case.

We recommend to read an article about bleeding when taking birth control pills. From it you will learn about the effect of oral contraceptives on a woman's body, the causes of daub during the ovulation period, as well as the causes of bleeding.

Depo-Provera is one of the effective drugs for treating various gynecological pathologies. The drug can have a significant impact on the work of the hypothalamic-pituitary system and lead to various violations of menstrual function. Own periods and the possibility of pregnancy is restored on average 2 to 3 months after the end of the use of funds.

This hormonal contraceptive, they begin to take in the second half of the cycle. . Provera. Hormonal drugs contain progesterone analogues. These drugs are prescribed after curettage, usually for 3-6 months.

The essence of artificial menopause and its manifestations. Drugs prescribed for the introduction of artificial menopause. The state of the woman's body after release.

Depo-Provera (medroxyprogesterone). As a result of taking the drug, the maturation and disintegration of the egg does not occur, that is, the sex hormones stop supporting the development of uterine mucous tissue.

Hormonal contraceptives, in addition to the main effect - protection against. Hormonal drugs simultaneously treat these conditions. . Therefore, it is desirable to use prolonged forms (Depo-Provera, etc.

For this are the drugs that induce the work of the ovaries: “Clomiphene”, “Prophase”, “Horigonin”, “Pregnil”. The first remedy is drunk 1 tablet each, starting on the 5th day of the cycle and on the 9th.

stronger contraceptives include combined contraceptives consisting of progesterone and estrogen. . It is these double-acting drugs to prevent pregnancy can cause.

Drug action

The active ingredient of Depo-Provera - medroxyprogesterone - belongs to the group of progestogen hormones, and is a chemical derivative of progesterone, which, together with estrogen, performs very important functions in the body. For example, progesterone is a hormone of pregnancy, because it is its effect that causes the growth of the placenta, through which the developing baby eats. The drug does not have the effects of estrogen, but has a low level of activity characteristic of androgenic hormones.

Depo-Provera on the principle of feedback leads to a decrease in the production of pituitary hormones (for example, follicle-stimulating - FSH, luteinizing - LH, etc.), which leads to the cessation of normal growth and maturation of follicles in the ovaries of a woman. The absence of follicles in the ovary causes the absence of ovulation and the impossibility of conception. Also Depo-Provera reduces the severity of neurovegetative disorders in the period of the onset of menopause, increases the viscosity of the mucus of the cervical canal, increases the number of maturing cells of the vaginal mucosa.

Special doses of Depo-Provera can suppress testosterone synthesis in the testicles of men. At the same time, there is an anabolic effect of the drug, manifested in an increase in body weight, acceleration of growth, metabolism, etc.

High doses of the drug have good antitumor activity against tumors that are sensitive to hormones.

The absorption, distribution and removal of Depo-Provera from the body

The drug is injected intramuscularly, with the result that a “stock” of the drug is formed at the injection site, which slowly enters the bloodstream. Such a slow release of the drug allows for a long time to maintain the necessary therapeutic concentration in the blood. The maximum concentration of the drug is achieved in the interval from 4 to 20 days after intramuscular injection.

The constant circulation of Depo-Provera in the bloodstream is also ensured by the fact that 90-95% of the drug binds to proteins, and, as necessary, is released in free form. Depo-Provera has a high ability to accumulate, therefore, the complete elimination of the drug from the body is possible only after 7-9 months after the last injection.

The drug has a high penetrating ability that allows you to bypass the blood-brain barrier and get into the brain tissue, the placenta and breast milk.

The removal of the drug from the body through the kidneys and liver. The kidneys excrete just under half of the drug (44%) in the urine in a completely unchanged form. The liver subjects medroxyprogesterone to various transformations, and secretes its derivatives (metabolites) into the intestine with bile. Further, the metabolites are excreted.

The rate of elimination of the drug is determined by a special indicator - the half-life (T 1/2). The half-life is the time interval over which half of the administered dose is eliminated.

Depo-Provera in the treatment of cancer

For the treatment of malignant tumors of the endometrium or kidney, the drug is used on 400-1000 mg per week. After stopping the tumor growth and progression of the disease, they switch to a maintenance dose of 400 mg per month.

A malignant neoplasm of the mammary gland is treated according to the following scheme: 28 days — daily administration of the drug in 500 mg, then twice a week — also in 500 mg. The drug is taken before the regression of the tumor.

For the treatment of prostate cancer in men, the drug is used twice a week, in the form of intramuscular injections of 500 mg for 3 months. After the main course, it is necessary to apply a maintenance dose of 500 mg weekly.

Depo-Provera in the treatment of gynecological diseases

For treatment endometriosis Intramuscular injections of Depo-Provera are used weekly in a dose of 50 mg, or once in two weeks in a dose of 100 mg. The course of treatment of endometriosis is six months. Another course of treatment for endometriosis is based on taking Depo-Prover tablets at a dose of 10 mg 3 times a day for 90 days. Taking the pills should begin on the first day of the menstrual cycle.

Elimination climacteric disorders neurovegetative origin (hot flashes, fever, sweating, etc.) using Depo-Provera is carried out as follows: intramuscular injection once every 120 days in an amount of 150 mg. At the same time, the condition should be monitored, and the benefit associated with the possible risks of side effects.

Termination uterine bleeding eliminated by taking Depo-Prover tablets at a dose of 5-10 mg per day for 10 days. After 3-7 days, bleeding develops, caused by drug withdrawal. Then apply a course of treatment for 2-3 menstrual cycles, which start from day 16.

Contraception with Depo-Provera

For the purpose of contraception, Depo-Provera is administered intramuscularly with 150 mg - one injection every three months. An injection is made into the buttock or deltoid muscle (shoulder), after carefully shaking the contents of the bottle with the drug. The drug is collected in a sterile, disposable syringe, which is gently shaken to obtain a homogeneous suspension. Then a needle is put on the syringe, from which the cap is removed. The injection site is treated with an antiseptic, then the drug is injected.

Depo-Provera is valid for all three months after administration, while the effectiveness of birth control is 99.5%.

Starting the use of Depo-Provera for contraception is necessary only in case of complete certainty that there is no pregnancy. Therefore, the first injection is made on the 5th day of the normal menstrual cycle, or on the 5th day after birth, provided that the baby is no longer breastfed. If a woman carries out breastfeeding, then Depo-Provera injection should be made no earlier than six months after delivery. After medical abortion in the period up to 12 weeks of pregnancy, you should immediately inject Depo-Provera. If the abortion was performed for more than 12 weeks, then the use of Depo-Provera should be started 2-4 weeks after medical manipulation. After the first injection, the next one should be done in 12 weeks, but not earlier than after 89 days.

The contraceptive effect of Depo-Provera in most women is accompanied by irregular menstrual irregularities. Most often there is irregularity and lengthening of the cycle, or, conversely, abundant and prolonged menstrual bleeding. Further use of the drug can lead to complete cessation of menstruation (amenorrhea).

The beginning of the use of Depo-Provera may provoke irregular intermenstrual bleeding or bleeding, which is not a pathology, since it is a reaction of the body to hormones injected. After a short period of time, the bleeding will pass without additional intervention. With prolonged and incessant bleeding, estrogen hormones are prescribed - 25-50 μg of ethinyl estradiol between 7 and 21 days, for two menstrual cycles.

The use of the drug significantly reduces the risk of inflammatory diseases in the genital area, including vulvovaginitis, caused by Candida fungi. Taking the drug contributes to weight gain, so you need to carefully monitor nutrition and exercise regularly.

One of the negative aspects in the use of Depo-Provera is the impossibility of refusing to take the medication simultaneously in the development of unpleasant sensations or side effects that significantly reduce the quality of life. The drug after the introduction will have an effect all three months.

In general, contraception with Depo-Provera is recommended for mature, adult women who already have children and are not planning to become pregnant in the coming years. The hormonal background of the female body can recover for quite a long time after using Depo Prover, therefore, young women who are planning a pregnancy in the long term should not use the drug. In this case it is better to prefer hormonal contraceptives in the form of tablets.

Contraception using Depo-Provera is best suited for women with the following conditions:

  • hypertonic disease,
  • venous thrombosis,
  • systemic lupus erythematosus,
  • diabetes,
  • heart defects
  • smoking over the age of 35,
  • multiple abortions,
  • endometriosis,
  • uterine fibroids,
  • mastopathy.


Depo Provera is a highly effective, convenient and reversible method of contraception. It reduces the amount of menstrual bleeding and reduces dysmenorrhea. Like other progestogen contraceptives, it reduces the risk of PID, causing a change in cervical mucus. In addition, there is a decrease in the frequency of endometriosis.


The main disadvantage of Depo Provera, especially for women concerned about their weight, is weight gain. This is due to increased appetite, and not fluid retention, weight gain is about 1 kg per year.

Another side effect (like other forms of progestogen contraceptives) - a violation of the cyclical bleeding. If a woman is warned about this in advance, the risk of not using this contraceptive further is less. For most women after the first injection of Depo-Provera, the number of days of light bleeding or spotting increases. It should be warned that it may be necessary to constantly use daily panty liners, but menstrual pads are rarely required. After two or three injections in most women, the cycle normalizes. By the time of the third injection, most women experience amenorrhea. It scares many women, because in menstruation, they see confirmation that they are not pregnant. However, other women consider the absence of menstruation convenient, so they prefer to use Depo-Provera further. In general, by the end of the first year, 30% of women have a regular cycle, 25% have amenorrhea, and the rest have irregular bleeding. After 5 years of using Depo Provera, only 17% of women have a regular cycle, most women have amenorrhea (80%), and 3% have irregular bleeding.

Another disadvantage for some women is the delayed recovery of fertility. Normalization of the cycle on average occurs after 9 months. after the date of the injection, which was to follow the last one. Depo Provera does not cause an irreversible violation of fertility.

Other side effects include fatigue, depression, decreased libido, vaginal dryness, bloating, dizziness, breast tenderness, calf muscle spasms and headache.

Issues that must be discussed when consulting, are listed below.

Questions to be clarified when consulting on Depo-Provera

  • Probable weight gain.
  • Fertility recovery is delayed.
  • There is a theoretical long-term risk of osteoporosis.
  • The effect of a single dose lasts at least 12 weeks.
  • Amenorrhea may occur. A woman should know that monthly menstruation is not a prerequisite for women's health.
  • There may be frequent irregular bleeding.

At what time of the menstrual cycle is it possible to introduce Depo-Provera?

In the presence of menstruation, the first injection should be made before the 5th day of the cycle. Start of action is immediate.

Depo-Provera can be administered in the postpartum period, but it is advisable to postpone the injection for 5-6 weeks. after childbirth, to reduce the risk of severe and prolonged bleeding.

When the drug is injected for 7 days after a spontaneous or induced abortion, the contraceptive effect is achieved immediately.

Is it possible to give a trial dose or to prescribe a mini-drink first, if a woman doesn’t like the idea of ​​irreversible hormone injection for 3 months?

The test dose is not recommended because the contraceptive effect may not be sufficient: an injection of 50 mg of the drug may not provide suppression of ovulation even for 1 month. Taking the drug inside and taking a mini-drink is not equivalent to the intramuscular injection of Depo-Provera and should not be used to check the patient's reaction.

Depo Provera causes osteoporosis?

A small study showed that after the abolition of Depo-Provera, bone density may increase. Наибольшие опасения риск остеопороза вызывает у подростков, у которых формирование костной ткани не завершилось. У женщин, собирающихся применять Депо-Провера более 2 лет, рекомендуется тщательно взвешивать соотношение риска и пользы.

Shortly after the introduction of Depo-Provera, some women develop severe bleeding. What to do in such cases?

The cause of severe bleeding is due to the small Depot-Provera endometrium thickness. Unlike heavy menstrual bleeding caused by excessive development of the endometrium under the influence of estrogens, when progestogens are prescribed for stabilization, for bleeding with the use of Depo Provera, the introduction of progestogens can worsen the situation. Therefore, premature administration of the next dose of Depo-Provera will not be a solution to the problem. In such cases, the patient should be given estrogens in any convenient form, for example, 30 mcg of COCs. This will ensure sufficient development of the endometrium. After 2-3 weeks. treatment estrogens should be canceled and examined by the patient. With the normalization of the cycle, you can continue to use Depo-Provera.

Some patients are late with repeated injections (they arrive more than 2 weeks after the date of the planned injection). Will Depo Provera be effective?

Late treatment is a frequent occurrence in young women leading a promiscuous life (using drugs, for example) and in patients with mental illness. In these situations, follow the recommendations given in Table. 3.4.

With the onset of pregnancy, the risk of ectopic pregnancy and spontaneous abortion is not increased. There are no serious malformations associated with the use of Depo-Provera, but masculinization of the female fetus is possible (transient clitoris enlargement) and an increase in the frequency of hypospadias.

Pregnancy after taking birth control pills: the effect on the unborn baby

To worry about the effect of oral contraceptives on the health of the unborn child is not particularly worth it. If you miss taking at least one or more birth control pills, the chances of getting pregnant will increase significantly. If, nevertheless, a pregnancy has occurred on the background of taking oral contraceptives, and you wish to carry the baby, then remember that taking these pills will not affect the health of the future baby. As the statistics show, the number of premature termination of pregnancy or the birth of children with any abnormalities as a result of the occurrence of pregnancy during or immediately after discontinuation of hormonal drugs does not exceed the usual level.

Many women mistakenly believe that after the abolition of long-term oral contraceptives, they should immediately become pregnant. In this case, the age of the patient should be taken into account; the older the woman, the lower the chances of conceiving and carrying out the child, which is also connected with the oppression of the reproductive function. But prematurely sound the alarm is not worth it. You should contact an infertility specialist if you cannot become pregnant within one year after the removal of contraceptives, provided that you have regular sex life.

Note: After pregnancy, women, taking care of the normal flow of labor, are in search of a good maternity hospital. In St. Petersburg, the maternity hospital 18 offers women the service of a personal obstetrician-gynecologist, who will conduct a qualified pre-pregnancy examination, guide you during pregnancy, childbirth and the postpartum process.

Country in SHOPe: Friends Lena and Marina - Contraceptive (Issue 5)

That is why gynecologists advise, firstly, not to delay the pregnancy - everything has its time, secondly, to monitor their health and prevent the development of chronic inflammatory processes, and thirdly, to take breaks while taking oral contraceptives. Approximate scheme: 2-3 months break after each full year of taking the drug.

When a woman taking birth control pills decides to have a baby, this can happen as soon as the month after it is canceled. By the way, in any case it is necessary to finish the started packaging to the end, otherwise the risk of hormonal disturbances increases.

During the first three months after the cancellation of OK for pregnancy, there are quite high chances, and if it happens so - do not worry, your previous protection will not affect the development of the baby (even if the pregnancy started on the background of OK therapy, it develops safely). But doctors advise to wait some time, giving the ovaries the opportunity to fully recover, and during the break to undergo a full examination before planning pregnancy. Often it is diseases and disorders that are an obstacle to the happiness of motherhood, and not birth control pills.

If the desired pregnancy does not occur within one and a half years and longer after the cancellation of hormones, then the help of fertility specialists will be needed. Your pregnancy may need to be stimulated. Do not tighten with it. Go through the necessary research and - and everything will work out for you!

Preparation Depo-Provera

The drug belongs to the group of progestin drugs. The composition contains the hormonal substance medroxyprogesterone acetate. The activity of estrogenic and androgenic hormones stops, ovulation does not occur due to the fact that the follicles cease to mature. The drug Depo-Provera (DMPA) inhibits the growth of the endometrium and affects the thickness of cervical mucus. Before treatment, the patient is examined and the risk of minimal complications caused by the gestagen-containing medication is assessed.

Depo Provera Application

Indications for use of the product are:

  • contraception,
  • painful menstruation,
  • endometrial hyperplasia,
  • elimination of vasomotor manifestations at the beginning of menopause,
  • prevention and treatment of endometriosis,
  • recurrence and metastasis of cancer of the kidneys, mammary and prostate glands.

In cases where the injection is used as a contraceptive, doctors point out its advantages over similar means:

  1. Suitable for women who are contraindicated in contraceptives containing estrogen.
  2. Placed 1 time in 3 months. A woman can forget about taking pills daily.
  3. It has a high level of protection against unwanted pregnancy.
  4. Reduces the risk of developing cancer.

Another application area for Depo Provera is hormone-dependent tumor therapy. For this, another dosage of the progestin is selected. Depot medroxyprogesterone acetate is used during the recurrence of cancer and in the event of metastasis. It reduces the metabolism of corticosteroid hormones if higher doses of the drug are used.

Depo Provera instruction

The drug has different uses, therefore it is available in different forms:

  • syringe with a medicine intended for a single injection - 150 mg in 1 ml,
  • 1 ml vial containing 150 mg of active substance
  • 3.3 ml vial containing 500 mg of medroxyprogesterone.

According to the instructions of Depo-Provera for pregnancy prevention, intramuscular injection is performed within 5 days from the start of timely menstruation 1 time in 3 months. The suspension should be shaken thoroughly, it has a thick consistency. When breastfeeding needs to be preserved, it is allowed to be prescribed for nursing women according to the instructions, but the risk of complications for the baby is evaluated, because medroxyprogesterone is transmitted through milk. The number of courses should not be more than 3, then take a break for 6 months.

For the treatment of other diseases, the doctor individually determines the duration of treatment. The dosage is set depending on the type of oncology:

  1. Cancer of the endometrium and kidney - 400-1000 mg once / week. After improvement, the dose is reduced.
  2. Breast cancer - 500-1000 mg / day for 4 weeks. Then begin to put on 2 times / week for 500 mg.
  3. Metastasis of prostate cancer - 500 mg 2 times / week 3 months.
  4. Endometriosis - 50 mg per week, or 100 mg 1 time / 2 weeks for six months.

To relieve unpleasant manifestations during menopause, you should put injections of 150 mg once every 12 weeks. Depo-Provera with endometrial hyperplasia is prescribed in the same dosage as with contraception. After the drug is injected, care should be taken to ensure that a seal does not form at the injection site. The substance is absorbed into the blood gradually, with an allergic reaction and non-compliance with the rules of hygiene may begin inflammation.

Side effects of Depo Provera

Like many hormonal medications, medroxyprogesterone not only helps to treat serious illnesses, but also causes complications. If you feel unwell after you start taking, you should immediately consult a doctor. Side effects of Depo Provera include:

  • disorders of the urogenital system - irregular bleeding, menstrual disorders, anovulation, changes in the viscosity of the cervical mucus, engorgement of the breasts,
  • failure of the nervous system - drowsiness, dizziness, decreased concentration, convulsions, headaches,
  • skin irritation - urticaria, itching, acne, allergic rash,
  • development of diseases of the cardiovascular system - increased blood pressure, thrombophlebitis, heart failure, tachycardia, thromboembolism, myocardial infarction,
  • disorders of the digestive system and liver - slowing down the metabolism, weight gain, vomiting, loss of appetite, nausea, cholestatic jaundice, diarrhea,
  • temperature rise,
  • swelling in the legs.

Indications for use

The drug has contraceptive action. is he suppresses ovulation, promotesincrease the viscosity of mucus in the cervix, interferes with endometrial development for egg implantation. The production of pituitary gonadotropin is reduced by steroid hormones, while development of hormone-sensitive malignant neoplasms is blocked.

The drug is used to:

  • prevent unwanted pregnancy
  • treatment of endometriosis, as well as endometrial hyperplasia in menopause,
  • elimination of vasomotor disturbances in menopause,
  • mastopathy therapy,
  • relieve uterine bleeding,
  • treatment of recurrent or metastatic cancer of the breast, endometrium, kidney, prostate gland.

Instructions for use Depo-Provera

A drug administered intramuscularlyrespecting the rules of hygiene. The bottle or disposable syringe is well shaken to obtain a homogeneous solution.

With contraception 150 mg with an interval of 12 weeks. The first injection is administered on days 1-5 of the menstrual cycle. After delivery on the 6th day in the absence of breastfeeding. At the termination of lactation or on the 6th week after birth (while maintaining breastfeeding). In this case, breast and cervical cancer should be excluded.

Breast cancer is treated as follows.: The first 30 days, 500 mg daily, then twice a week, 500 mg each injection. The course of treatment depends on the time to achieve a positive effect.

In the presence of malignant tumors of the kidneys and endometrium enter 400-1000 mg every seven days. When the desired therapeutic effect is achieved, 400 mg is applied once a month.

With metastasis of prostate cancer twice a week, 500 mg is administered for three months. Then 500 mg every seven days.

With postmenopausal treatment The course of therapy is quite short and is chosen individually.

Endometriosis is treated according to the scheme.: 50 mg once a week or 100 mg once every 14 days. The course duration is six months.

Monthly after Depo Provera

Such deviations occur for the following reasons:

  • large dosages and a long course of treatment require more time to restore the cycle,
  • high sensitivity of the pituitary and hypothalamus, even after a single application, causes a prolonged absence of menstruation,
  • Slow excretion of the drug in violation of the functions of the kidneys and liver,
  • with the coincidence of the menopause period with the beginning of the course of drug treatment, while the menstrual periods no longer begin.

Pregnancy at the end of the reception Depo-Provera

Restoration of ovulation occurs 1-3 months after discontinuation of the drug.however, sometimes it takes more time. If you want an early pregnancy, the doctor selects an individual regimen of drugs containing estrogen and gestagen.

Full restoration of fertility occurs within 9-12 months. after the course. There are cases of pregnancy 30 days after the completion of using Depo-Provera.

Women who used the drug as a contraceptive, noted its effectiveness. An injection every three months is very convenient for most patients. The drug reliably protects from conception.

Cases of poor health were noted: lethargy, fatigue, impaired concentration. After using the drug, an increase in body weight is observed.

Opinions of experts are ambiguous. Some advise the use of medication for patients of all age groups. Others believe that the remedy is suitable for more mature women. Numerous reviews of girls indicate the difficulties of conception after the use of Depo-Provera or the complications of pregnancy.


The drug has a high rate of efficacy. He effectively fights tumors and gynecological ailments. Tolerability of the drug is purely individual. Reception Depo-Provera is carried out only under the supervision of a specialist. In the appointment of funds take into account the need for therapeutic effect and potential risk. A serious consequence of the use of the drug is a violation of fertility. If a woman does not plan to have children, the problem is leveled.