Ketorol (tablets, gel, injections) - instructions for use, analogues, reviews, price


How to reduce pain with monthly painkillers. Ketorolac, Ketorol, Ketanov is the most powerful analgesic of this series, it is taken not more than 3 tablets per day

Ketorol, ibuprofen. lie folded

Popular method: drink a cup of hot tea, nurofen, warm socks, and a hot-water bottle under your feet.

In addition to painkillers such as Nimesil, peony tincture helps well.

Drink but shpa. relieves muscle spasm, reduces pain

Since I myself had a problem with pain during menstruation, I tried many medicines. I was advised to give Ketorol to the pharmacy, I forgot about the pain in general.

Pain during menstruation is a spasm. At first, I simply sat on my stomach, almost without moving, slowly moved, I was very careful. In general - just endured.
And then somehow she started lying on the couch to bend with her whole body - to strain the stomach and relax, to arch the back, since the ache was unbearable. And what do you think? As it intuitively started gently, so press the press. 10 times folded, decomposed and feel much better, since the blood was distributed further outward of the spasm. and thus removed the spasm itself, and at the same time the pain!
I began to download more press - and in general everything went.
I began to press the press before each monthly and at the same time massage the inside. I did this for several months - and now I forgot about pain in general. Plus, the stomach is in place, plus the digestion returned to normal.
Damn, and these are just light physical exertion - which in fact greatly helps the uterus to be supple and without cramps.
You can drink and fees - the effect is the same - relieves spasm. But I'm too lazy fees. And the press is not lazy - there are many bonuses from it.

What pills would you recommend to drink for pain during menstruation?

Analogs of Ketorol in the presence of available structural analogues. Use for the treatment of dental, headache and other types of pain, during menstruation in adults, children, as well as during pregnancy and lactation.

Only ketorol helps me

Noshpu usually take.

Noshpa helps me, although my mother is not

Ketorol helps well, you can also take a pill of analgin and noshpu together to drink. The pain during menstruation is a spasm of the uterus. I gynecologist advised noshshu as the most benign remedy.

Kitorol, Kitanol .Tempalgin.

Ketanov - I am only saving myself now, although earlier the usual spasmalgon helped.

What to do Konda stomach hurts, during menstruation

Ketorol to help.

Girls, do you often have pain during menstruation? Everyone says it’s okay. I’m not hoping for Ketorol? I was in shock when my sister was advised by someone to give me Ketorol injections during her period!

Dolar in 15 minutes to quench the most burning pain.

Buy analgesics that are commercially available and save themselves
as an option very well from such pains, ketorol, ketanvo and dexalgin help well

For menstruation painkillers, which ketorol and capsules are more painful to buy in capsules for pain during menstruation?

Analgin with Dimedrol, make an injection, it helps, but it puts a lot of heart, you need to be treated by a gynecologist, but as an urgent remedy it will help, but only if you do not need sleep, without Dimedrol, I never sleep

How to remove pain during menstruation. 1. The simplest is to take a pill of any analgesic with the exception of aspirin and aspirin-containing drugs or antispasmodic. It may be analgin, baralgin, spazgan, no-shpa, ketanov ketorol, ibuprofen, nimesulide.

The drugs you mentioned have the same active substance, they are analogues. Diclofenac (voltaren) - candles rectal. You can also use papaverine. It has an antispasmodic effect. Plus candles in that they begin to act much faster and more efficiently than tablets taken inside and have a much more active anti-inflammatory and analgesic effect. In addition, the load on the liver and stomach is reduced.

My stomach hurts during menstruation, what should I do?

Ketorol to help.

With toothache, Ketorol is an excellent and effective drug that relieves discomfort quickly and for a long time. Can ketorol be used during menstruation. Just in the first days of menstruation the lower abdomen hurts.

And when I have a stomach ache from menstruation, I drink a load-pa and lie with the music all is well and it will pass

If you really need to go to the doctor. This may be endometriosis.

How to get rid of pain during menstruation?

Ketorol helps me.

Types of menstrual pain. Menstruation may be accompanied by several unpleasant symptoms. Headaches during menstruation such as Aspirin, Nurofen, Sumatriptan, Zolmitriptan, Ketorol relieve headaches during menstruation.

"Ketanov" drink a tablet or "Drotaverin" (analogue spit)

Took, baralgin, pentalgin

Try mastodinon drink, helped me

To eliminate a sufficiently strong pain, it is recommended to use Ketorol in the form of injections for intramuscular administration. I use Ketorol only for severe pains, mainly for menstruation and inevitable headache.

Do you have monthly pains from the very beginning?
Of course the stomach can pull. But there is an unbearable pain, where only strong painkillers help, the same ketanol. These painful sensations do not appear just like that, maybe due to some kind of disease. Chilled can.
We must go to the doctor, check.

Which pain reliever is better from pain during menstruation? But such that less damage to the liver:. Ketorol or Novigan?

Pills Paracetamol, Analgin, Ketorol and Papaverine, Ibuprofen and Solpadein help eliminate menstrual pain. In case of strong or sharply appearing pains, the doctor may prescribe pain-relieving injections during menstruation.

There are special yoga exercises that not only do not harm the liver, but even help her. For example,

All painkillers are about the same harm. Choose what suits you.

Cognac ... Can and hot tea.

Met in the messenger requests to help with painful periods. The recipe is simple.
On the first day of your period, brew 1 teaspoon of horsetail with a glass of boiling water, let it brew and take 1 tbsp. spoon every 2 hours, in the following days - less. Analgesic pills will become redundant.

The stomach hurts at monthly

Insurgent drink. Either Ketorol, or Naiz)))

Causes of pain during menstruation Pain during menstruation is the result of excessive uterine contractions. This may be analgin, baralgin, spazgan, but-shpa, ketanov ketorol, ibuprofen, nimesulide or others. It is better to consult a doctor beforehand.

This is normal .. the same situation with the girl. Take painkillers. Revalgin, for example.

Maybe he could go to the doctor, and maybe it would cost as much, and maybe the plantain should be attached to the belly, or maybe the next 50 years could suffer, and there they would end

Any pain is not the norm.

Ibuklin helps me

What to do if the pain during menstruation is not tolerable.

Take a pill. pentalgin helps me. in general, strong pains are not good. . Go to the doctor.

Ketorol I drink, baralgin, spazmalgon. it hurts like hell for menstruation, if I didn't have time to take the pill on time, I had to call an ambulance, I lose consciousness from the pain. I have not heard this about ketanov! just his saw and usually, or even spazmalgon!

There are herbs that weaken the pain I can give, recipes.

To the doctor! with this one is not joking.

You will help visceral massage. I can give references, there is no time to explain physiology to you now.

I drink citramona pill. it helps me, although I went to consult a gynecologist, she advised me to drink any hormonal contraceptives, she says the pain goes away. There is no threat of getting fat. But the monthly will be too heavy. every hour I ran through the gaskets.

Visit a doctor. Unbearable pain during menstruation is NOT NORMAL.

To relieve pain during menstruation, it is advised to drink the painkillers Ketorol, aspirin analgesics. Today, modern pharmaceuticals offer new modern pills that effectively help with the pains during menstruation Nimisil.

Find out the cause of pain, this should not be. Do a pelvic ultrasound, take on hormones and check for all infections. Go to the gynecologist.

Painkillers will help you. to the gynecologist is also useful to go. that's just all the stories that "this is not normal," "pain during menstruation should not be" - in my opinion, is nonsense. I do not know any woman who would not have a stomach ache during menstruation. we lose blood, the body pain warns us about this. everything is logical.

This not normal. But it is often useless to go to the doctor with this problem, there is very little chance that he will be able to help. It is necessary to go to several different ones, listen to more different tips, then you can choose something for yourself. Hormone treatment can help. Ketorol tablets are not bad as painkillers. Childbirth is treated very well, much less pain after childbirth - ketorol is already good at helping. If someone has a "baby womb" - there will also be severe pain. Look for a very good doctor.

What pills to drink during menstruation

Ketorol, ketonal the most effective is if with pain!

Most girls who suffer from pain during menstruation and are forced to drink pills are familiar with the name of the pill as No-Shpa. Analgesics, such as Nise, Ketanov, Ketorol, etc., are not recommended to be taken without a doctor's appointment during menstruation.

I buy tamipul for my beloved. immeno from these pains.

How to relieve pain during menstruation ?? very sore bottom

Symptoms of overdose, which causes ketorol dyspepsia, nausea, abdominal pain, the appearance of peptic ulcers with erosive bowel disease, acidosis, impaired renal function.

Ketorol half tpblet or nise. Try nemisil still.

Nurofen .. I also suffer every time with such a problem .. sometimes even it does not help .. I have to call the doctor so that they can do it .. they nosy with analgin

Drink nettle tincture a few days before the beginning of menstruation, and in the first two days.
but in general, if it hurts a lot, it's better to see a gynecologist. should not be very strong pain.

Kitanov. No more than 2 tabl per day.

Ketorol! 1 tablet. If intolerable pain, then 2! The tablet is just super! If the tablets are not at hand, then apply ice to the lower abdomen for 20 minutes.

Ketorol with toothache how to take? For quick relief of pain, it is better to use intravenous infusion active agents. You should also not take medicine during menstruation for women. It is forbidden to take ketorol with others.

How to relieve pain during menstruation?

Drinking chamomile tea, strong.
You can no-silo, but in no case tamipul!

How to relieve pain during menstruation? In pharmacies to the choice of the buyer are many drugs that help to cope with the pain during menstruation. While I did not stumble upon ketorol, nothing helped. Now he is on prescription and I suffer again.

Take a course remensa well helps everyone who has such problems

It is so natural that you can be patient. No shpa. Also very good. A good gynecologist may recommend specific medications to relieve severe pain.

I am on the first day of the CD, even when there is still nothing really beginning to hurt, I drink solpadein, it helps. It is possible to drink no-shpu.

A warm heating pad on the lower abdomen, but the shpu and relax. Pain, rather, because of the narrowness of the hole in the cervix, after the birth of the first child usually all goes away.

I, too, with menstruation, only save Ketorol! answer. In connection with which I was covered with a headache in the temples. She drank a pill of Citramon, did not help, found Ketorol in the first-aid kit at work.

How to ease the pain. How to relieve pain during menstruation if noshpa Ketorol and other painkillers do not help?

Try antispasmodics in injections, and in general no one can tell a better gynecologist. Apparently there is still inflammation)))

For some, the feeling of painful periods is quite tolerable, but for others it is not. What can be done in such a situation, what is the best remedy you can choose from heavy discharge, which is better to choose pain pills for menstruation?

People help! Right now, die! Nightmarish pains during menstruation

Need to give birth
or to the dentist
revalgin helps me

By the way, in the struggle for painless critical days you should not rely on tablets for pain during menstruation from the very beginning. Prevent menstrual pain and enhance the effect of painkillers can by adjusting the diet.

Antispasmodics should be taken 3-4 days before the menstruation, then you will remove the spasm of the cervical canal in advance.

2 tab. no-shpa + 1tabl. analgin.

It is better to consult a gynecologist. Looks like something serious.
When menstruation should be tolerated, and sometimes without pain. If nothing helps at all. Then go to the doctor.

Well, about the nightmarish pains, you got excited. Be patient - from this no one has died.

Painkillers and candles for menstruation and menstrual pain. It is difficult to prescribe an anesthetic for menstruation, as it is necessary to study the causes of nosology. There is an extensive list of drugs.

Nimulid, a hot water bottle on the stomach and 50 g. Brandy. And tomorrow to the doctor.

Nurofen help. He is very strong. .
if painkillers do not help, then you may have inflammation .. or your ovaries got cold .. check

Of course, the best advice will be given by a gink doctor, and from myself I can say that with monthly pain there should be no pain at all, slight pulling pain in the lower abdomen, which can be easily relieved by analgesics, if the pain is VERY strong, this is a deviation from the norm and consequently evidence of an inflammatory process in the small pelvis.

One injection of Voltaren, is in any pharmacy, helps after 15 minutes, a maximum of 100%.

Accept what Sheba wrote - it helps for sure. A heating pad is not allowed, but a doctor is necessary.

She could walk, left her daughter to her husband, got to the injury. They checked, they said that there was a very strong bruise of the soft tissues, Ketorol was advised against the pain. Especially since I have already completed breastfeeding.

Father does not pardon children?

Do not die!)) But - shpa should help. Since it hurts so much, drink 2 pcs.

Try special candles ... They act faster and immediately remove the spasm. . From them it becomes much easier .... Ask your pharmacist at the pharmacy ...
And try to distract yourself with something, do not constantly think about pain, do not concentrate all your attention on it. . and it makes it worse ... All will pass! :)

This is called a sharp belly! very similar to acute inflammation of the appendages. Do not suffer - just call an ambulance. Make an injection, the pain will go away and fall asleep. Or hospitalized. . be sure to call. . You can not tolerate!

What are the strong pain relievers: ketorol, ketanov, ketonal, spasmalgon? to relieve pain during menstruation.

Tablets are effective for toothache, for headaches, for pains that occur during menstruation, after injuries, in the postoperative iKetorol in ampoules, like the tablet form of the drug, used to relieve pain of moderate and strong intensity.

Yes, I am also for Ibuprofen. When menstruation is good.

Pain during menstruation is not normal, you need to go to the gynecologist. And if the pain is not tolerable, then any of the listed pain relievers will fit

Whom that helps. Tempalgin, Nice, etc.

Drugs for pain during menstruation. The content of the article. 1 Is it possible to reduce pain before menstruation. Anesthetic medicines of ketans, ketorol, baralgin, analgin.

Any antispasmodic (not painkiller!), And relaxation exercises.

Ibunal - a good anesthetic, and without side effects (saw after cesarean)

No shpa. 2 tablets

What painkillers do you have for menstrual pain?

How to take Ketorol with toothache? It is recommended to take the medicine when the pain is characterized by severe urgency. Yes, it really helps with menstrual pain, but it is recommended to use it only in extreme cases.

Baralgin, nothing else helps

No, so I suffer. The last 5 years, it turns out in the weekend, you can safely rush between the bed and the pot in the native walls.

Nise (the geneticologist advised how best to date)

If it does not hurt much then Pentalgin, and if it is severe, then ketanof.

Pentalgin, only he helps.

Ketorol is effective for toothache. Although in some cases it is better to take a niz to relieve a lighter toothache, it will be enough. I don’t know what the reason is, maybe in the -4 blood group, but Ketorol didn’t take pain, and what’s more, nausea was not added to the menses.

Spazgan or spazmolgon.
Saw prescribed by the gynecologist Nise and Vitamin E for 3 months (5 days before menstruation and 5 days during menstruation), but it did not help much, although the symptoms of PMS decreased

I had such problems in my psychics. Reached a faint and terrible pain. Somehow it was not at all on this occasion, but on the occasion of gastritis, I did this - aloe with a meat grinder (that is, not complying with the accepted technology, completely intuitively), twisted and squeezed the juice through gauze. On the steam bath added honey. It turned out a specific potion - the taste and color of course still the same. Saw before meals in 30 minutes on a tablespoon. Gastritis is gone, BUT - as a side effect - pain during menstruation is gone.

Yes, Nise is the best. I also advised the gynecologist. The thing is super.

All my life I suffer from menstruation from pain. Try ketorol, I completely sit on them during M and now I don’t know the problems, and their effect lasts for a long time, for about 10 hours somewhere. I also put the beat before the birth again.

Before the birth I was given only injections by analgin + novacaine and bainki
and now sometimes I drink ketans, it helps

Ketans are generally very strong painkillers! everyone fits his own. перепробовала но шпу, кетанов, пенталгин, нрофен, боралгин. мне подходит пенталгин. он и при миренях хорошо помогает.

Бускопан для женщин.

Что делать если сильно болит живот при месячных??

Consider some of them. Means for relieving pain during menstruation. Perhaps one of the most popular drugs for pain relief during menstruation is Ketorol.

Squat. 3 sets of 15 times

Drink painkiller or lie on your stomach

Ketorol for toothache. Toothache is considered one of the most powerful and unbearable types of pain. Perhaps every person at least once in his life with her faces. Ketorol with a toothache. It also happens that severe pain began immediately. That she did not catch you by surprise.

How to quickly reduce pain during menstruation?

Analgin for headaches. With menstruation, there is abdominal pain in the bottom, they called an ambulance today, they made an injection in the ass. Ketorol Noshpa helped for 11-12 hours. Ketorol is used for many pains.

Nalgizin helps me well

Sedalgin + spazmalgon. They contain substances that enhance the actions of each other.

What pills can you take for pain during menstruation? Pain pills for menstruation are sometimes the means to help quickly and effectively during critical days.

People help me ask me when menstruation is very painful lower abdomen what to do

It's okay, drink ketorol.

I took Ketorol while having a toothache. During 2 weeks, nothing good happened. No good remedy. There was a very painful tooth, I bought Ketoral tablets, and in one day I drank the fifth pill. pain manifests itself already after 2 hours.

Drink flaxseed oil 2 tablespoons per day. And the pain subsides and vitamins.

No, this is not normal! Go to the toctor, he will tell you something with a desire. Ways and go to FGS

This is usually normal.

This not normal. I myself suffered, until I restored the hormones, now I stand such days without pills!

Ketorol with monthly pain. is a medical portal for online consultation of pediatric and adult doctors of all specialties. Expensive specialists, please help me, I am 24 years old, I have been having wild pains during menstruation for 7-8 years, I went to doctors.

Gynecologist will help, should not hurt much.

What do you take for menstruation, so as not to have a stomachache?

The use of ketorol. Ketorol is used for moderate and severe pains of various origins. But more often it is the pain arising on the background of injuries of severe bruises, fractures, sprains, cut and gunshot wounds, burns.

I do not use anything, but when it hurts badly, I simply tie a pelvis with a woolen scarf, if at home

“No-shpa” helps me only! 1 tab. 2 times a day!

Nurofen, Solpadein, Pentalgin - any of this

Very good help drops EDAS 139

No-spa, tempalgin, ibuklin. Be healthy!:)

Pain pills for menstruation, how quickly cope with dysmenorrhea. Rubric Ovulation of menstruation. More than half of women on the planet experience pain of varying severity during menstruation.

Candles Indomethacin immediately relieve pain.

Ketanov, Ketorol, whatever, if only I feel better ((((((((((((

1 Causes of painful menstruation. 2 Menstrual pain in adolescents. 3 How to get rid of menstrual pain? Among the strong painkillers Ketans and its analogues Ketanal, Ketorol are in demand.

How to reduce pain during menstruation? What are the drugs. drugs for this ??

Trigan d
Stuff 10 eat better

Almost every woman inevitably asks herself a question once a month. Well, for what do I need all this? . And it's not just about excessive irritability, nervousness, restrictions in clothing and the need to use personal hygiene products.

Go to the gynecologist, it is successfully treated

I always drank a dog along with analgin. and taught her daughter too. The truth is now instead of Analgin buy Pentalgin.

As a painkiller, solpadine helps well, and in general it is best to go to the doctor.

Leave your feedback on the use of Ketorol, which will help other site visitors. The drug is used in various diseases headache, toothache, with menstruation.

VIVASAN-Thymian cream. smear the lower abdomen, everything passes. and no pills! nothing to poison your stomach.

Spazmalgon helps a lot

No-shpa well helps. Perfectly relieves cramps.

Somewhere I have already seen this question) Spazmalgon and butadion, help)

Trigan d
Stuff 10 eat better
wow )) I remember 6 hawala pieces .. feeling is not very pleasant .. that is. I do not advise.
Generally no-spa, festal ..
I remember no-shpy overeat. it was bad PPC .. thought of the next world I’ll go away .. it still lowers the pressure .. that is. I do not advise nagging)

Ketorol has become an indispensable medicine in my medicine cabinet since I discovered it after the deterioration of Solpadine. I drink Ketorol in pills. He perfectly helps me personally from various pains - for menstrual, severe headaches, migraine-like pains.

I always help stopping analgin a couple of pills on the very first day, if I need more in a couple of hours. And that's it! Usually it saves.

This is not normal. There should be no pain at all. Only when menopause occurs.

I have severe pain in the lower abdomen during menstruation, if I do not take Ketorol, it comes to loss of consciousness. what to do?

Be sure to see a doctor! Ketorol, as I understand it, only anesthetizes but does not cure, it can get very bad all later. to the doctor

But whatever the intensity and localization of the pain syndrome, any person dreams of getting rid of it as soon as possible. With the exacerbation of many inflammatory diseases, doctors use Ketorol tablets for pain relief.

Consult a doctor.

As I understand you, I felt better after taking hormonal contraceptives in several cycles. After childbirth, the pain subsided almost completely.

Varieties, names and forms of release

Currently Ketorol is available in three dosage forms:

  • Gel for external use,
  • Oral tablets,
  • Solution for intramuscular and intravenous administration.

Accordingly, these three forms of release of Ketorol are also versions of the drug. Ketorol injectable solution is often referred to as "Ketorol injections" or "Ketorol" ampoules. Ketorol gel in everyday speech is often called "Ketorol ointment." When using these incorrect, but quite frequent in everyday speech, the names of Ketorol, it should be remembered that there is in mind a real-life dosage form, and not any new type of drug.

The gel is a homogeneous transparent substance with a characteristic odor. Solution for injection - clear and colorless, or pale yellow. Tablets are painted in green color, have a round, biconvex shape and engraved in the form of the letter "S" on one side. On the fault, the tablet is white or almost white, with a homogeneous structure.

The gel is produced in aluminum tubes with a volume of 30 g, a solution in ampoules with a volume of 1 ml, 10 pieces per pack, and tablets - 20 pieces per pack.

Ketorol - composition

The composition of all dosage forms of Ketorol as an active substance includes ketorolac in various concentrations. Thus, the tablets contain 10 mg of ketorolac, 30 mg in 1 ml in solution, and 20 mg in 1 g (2%) in the gel.

The composition of the gel Ketorol as auxiliary substances include the following components:

  • Propylene glycol,
  • Dimethylsulfoxime,
  • Carbomer,
  • Methyl parahydroxybenzoate sodium,
  • Tromethamine,
  • Purified water,
  • Fragrance "Drimon Indus",
  • Ethanol,
  • Glycerol

The composition of the tablets Ketorol as auxiliary substances include the following components:
  • Microcrystalline cellulose,
  • Lactose,
  • Corn starch,
  • Colloidal silica,
  • Magnesium stearate,
  • Sodium carboxymethyl starch (type A),
  • Hypromellose,
  • Propylene glycol,
  • Olive green.

The composition of the solution for injection The following excipients are included:
  • Sodium chloride,
  • Ethanol,
  • Disodium edetat,
  • Octoxynol,
  • Propylene glycol,
  • Sodium hydroxide,
  • The water is deionized.

Ketorol - recipe

The recipe for Ketorol solution is as follows:
Rp: Sol. "Ketoroli" 3% - 1 ml
D.t.d.10 amp.
S.Inject intravenously or intramuscularly in 1 ml

The recipe for Ketorol tablets is as follows:
Rp: Tab. "Ketoroli" 10 mg
D.t.d. 20 tabletae
S. Take orally 1 tablet every 8 hours.

The recipe for Ketorol gel is as follows:
Rp: Gel "Ketoroli" 2%
D.t.d. in tuba 30 g
S. Apply externally to areas of skin where pain is felt.

In all the above recipes, after the letters "Rp", the release form (Sol., Tab., Gel) and the name Ketorol are indicated in Latin in quotation marks, since it is commercial. In the second line after the letters "D.t.d." It indicates how much the pharmacist should give to the person who presents the prescription at the pharmacy. In the third line after the letter "S." already indicated for the person himself how to use the drug.

Therapeutic effect of the drug Ketorol

Ketorol has a powerful analgesic effect, as well as relatively weak antipyretic and anti-inflammatory effects. The drug belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs), which have all three properties (antipyretic, analgesic and anti-inflammatory) in varying degrees. In Ketorol, the analgesic properties are most pronounced, and the anti-inflammatory and antipyretic effects are relatively weak.

The mechanism of action of the drug is associated with its ability to block the work of a particular enzyme - cyclooxygenase . This enzyme converts arachidonic acid into prostaglandins - special substances that cause the development of an inflammatory reaction, pain syndrome and an increase in body temperature. Thus, Ketorol, blocking the work of cyclooxygenase, stops the production of prostaglandins, as a result of which it stops the formation of an inflammatory reaction and pain, as well as an increase in temperature.

However, Ketorol has such a powerful analgesic effect that it literally overshadows and overshadows the anti-inflammatory and antipyretic effects. Therefore, the drug is used precisely as an anesthetic.

Ketorol is not a narcotic analgesic and does not cause the following adverse effects:

  • Impact on the central nervous system,
  • Respiratory depression
  • The weakening of the peristaltic activity of the intestine,
  • Urinary retention
  • Bradycardia or tachycardia,
  • Increased blood pressure.

Ketorol can lengthen the bleeding time as it dilutes the blood and reduces the activity of the coagulation system. However, as a rule, clotting indicators still remain within the normal range. therefore Ketorol should be used with caution. in people suffering from bleeding disorders, for example, hemophilia, stomach ulcers, etc. Ketorol practically does not affect the mucous membrane of the stomach and other organs of the gastrointestinal tract, therefore it can be used for a short period of time without the danger of the formation of “aspirin ulcers”. However, prolonged continuous use of the drug (longer than six months) may provoke ulceration of the gastrointestinal mucosa, therefore Ketorol is not recommended for a long time.

Ketorol - indications for use

So, indications for use for tablets and injections Ketorol is the relief of pain of any localization and severity. This means that pills or injections can be used to eliminate dental, headache, menstrual, muscle, joint, bone pain, as well as postoperative pain, pain in cancer, etc. You should know that Ketorol is intended only for the relief of acute pain, but not for the treatment of chronic pain syndrome.

Indications for use of gel Ketorol The following states are:

  • Injuries (bruises, inflammations of soft tissues, ligament damage, bursitis, tendonitis, synovitis, etc.),
  • Pain after injury
  • Osteoarthritis,
  • Muscle and joint pain,
  • Neuralgia,
  • Radiculitis,
  • Rheumatic diseases (gout, psoriatic arthritis, ankylosing spondylitis).

When using any form of Ketorol, it must be remembered that the drug only relieves pain, but does not eliminate its cause and does not cure the underlying disease that caused the appearance of an unpleasant symptom.

Ketorol tablets - instructions for use

Tablets should be swallowed whole, not chewed or crushed by other means, but with a small amount of water. You can drink pills, regardless of the meal, but it should be borne in mind that Ketorol taken after a meal will be absorbed more slowly than before a meal, which, naturally, will lengthen the time of onset of the analgesic effect.

Tablets must be taken sporadically if necessary to stop moderate or severe pain. The dosage of Ketorol for a single dose is 10 mg (1 tablet), and the maximum permissible daily dose is 40 mg (4 tablets). That is, during the day you can take a maximum of 4 tablets of the drug. This means that one pill is enough for a person to relieve pain for several hours, after which it returns, and then you need to take a second pill, etc. To relieve pain without consulting a doctor, it is allowed to take Ketorol in pills for a maximum of 5 days.

If a person switches from using Ketorol injections to taking pills, then the total daily dosage should not exceed 90 mg for people under 65 and 60 mg for those over 65. Moreover, in these dosages the maximum permissible number of tablets is 30 mg (3 tablets).

Injections (ampoules) Ketorol - instructions for use

The solution for injection is packed in ampoules and ready for use. The solution is injected deep into the muscle (into the outer upper third of the thigh, shoulder, buttock, and other parts of the body where the muscles come close to the skin), having previously collected the required amount into the syringe from the ampoule. You can not enter the solution Ketorol epidurally or inside the spinal membranes.

For the introduction of the solution intramuscularly, it is necessary to use disposable syringes of small volume - 0.5 - 1 ml. The syringe and needle to it must be removed from the packaging immediately before the injection, and not in advance. For the injection, it is necessary to open the ampoule in the solution, dial the quantity with a syringe, remove it and lift the needle upwards. Use your fingers to tap on the surface of the syringe in the direction from the piston to the needle so that air bubbles will rise and detach from the walls. Then, to remove the air, it is necessary to slightly press the plunger of the syringe so that a drop appears on the tip of the needle. After that, the syringe should be put aside and the injection site should be treated with an antiseptic. The needle is inserted completely (to its entire length) perpendicularly to the skin at the chosen place, after which, pressing on the piston, slowly and carefully inject the solution. After the introduction of the solution, the needle is removed from the tissues and discarded, and the injection site is again wiped with an antiseptic.

If necessary, Ketorol from the ampoule can be added to the dropper and administered slowly along with other solutions. Ketorol is compatible in one bottle with the following solutions and drugs:

  • Saline,
  • 5% dextrose solution,
  • Ringer's solution
  • Ringer-Locke solution,
  • Plasmalite solution,
  • Aminophylline solution,
  • Lidocaine solution,
  • Dopamine solution,
  • Human short-acting insulin solution,
  • Heparin solution.

A single dose of Ketorol solution for people under 65 years old is 10–30 mg (0.3–1.0 ml) and is adjusted individually, starting with the minimum and based on the person’s response and the effectiveness of the relief of pain. You can re-enter Ketorol every 4 to 6 hours if the pain returns. The maximum allowable daily dosage of the solution is 3 ampoules (90 mg).

For people over 65, as well as those suffering from kidney disease or with a body weight less than 50 kg years, a single dosage of the solution is 10-15 mg (0.3-0.5 ml), which can also be administered every 4-6 hours if pain is returns again. The maximum permissible daily dosage of Ketorol for people over 65 years old, weighing less than 50 kg and suffering from kidney diseases, is 60 mg (2 ampoules).

The duration of continuous use of Ketorol without consulting a doctor should not exceed 5 days.

Ketorol gel - instructions for use

The gel should be applied to the skin clean, washed with soap and hands. It is necessary to avoid putting the preparation on the skin areas with injuries, for example, scratches, abrasions, burns, etc. It is also necessary to avoid and in every possible way to prevent the accidental hit of Ketorol gel in the eyes and mucous membranes of the mouth, nose and other organs. After treating the skin with gel, wash your hands with soap and wipe dry. After squeezing the required amount of gel, the tube must be tightly closed.

Before applying the gel, it is necessary to wash your hands with warm water and soap and the intended skin area over which Ketorol will be distributed. Then dry the surface of the skin and hands with a towel, then squeeze 1 to 2 cm of gel out of the tube and spread it in a thin layer over the area of ​​the skin in which the pain is felt. If the area of ​​the treated area is large, the amount of gel can be increased. The gel should be gently massaged into the skin until it is completely absorbed. On top of the treated area of ​​the skin, you can apply a breathable bandage (for example, a gauze or from a regular bandage, etc.) or not close it with anything. Do not apply air-tight dressing on skin treated with Ketorol gel.

The gel can be applied to the skin 3-4 times a day. Нельзя использовать гель чаще 4 раз в день, а между двумя последующими наложениями препарата на кожный покров необходимо соблюдать интервал не менее 4 часов. Без консультации врача гель можно применять максимум в течение 10 дней подряд.

special instructions

When using tablets and injections of Ketorol, it is necessary to take into account that after its cancellation, the effect on blood clotting persists for 1 to 2 days. If a person suffers from bleeding disorders, then with the use of Ketorol, it is necessary to monitor hemostasis indicators at least once a week (bleeding time, PET, APTTV, TV, fibrinogen, etc.).

It must also be remembered that a low circulating blood volume increases the likelihood of side effects from the kidneys.

Older people (over 65 years) have a higher risk of side effects of Ketorol, so they should use any form of the drug in minimal dosages.

If a person suffers from any diseases of the kidneys, then during the entire course of application it is necessary to monitor the function of the organ, regularly passing an urinalysis.

When using Ketorol solution or tablets, it is possible to increase the activity of hepatic transaminases in the blood (AsAT, AlAT), so the drugs should be used for liver diseases with caution and only short courses. If, on the background of the use of Ketorol, a malfunction of the liver develops, then the drug should be stopped immediately and consult a doctor.

Ketorol in combination with paracetamol can not be used for more than 5 days.

If only Ketorol tablets or injections are not sufficient for effective pain relief, then they can be combined with narcotic analgesics. In addition, tablets and injections of Ketorol can be used to reduce the amount of narcotic analgesics used.


Gel Ketorol Overdose impossible, but if it is accidentally released into the stomach (for example, licking from the lips, hands, etc.), it is necessary to induce vomiting, take activated charcoal or another sorbent (Polifepan, Polysorb, Enterosgel, etc.) and consult a doctor.

Overdose with tablets or Ketorol solution quite possible and manifested by the following symptoms:

  • Stomach ache,
  • Nausea,
  • Vomiting
  • Formation of peptic ulcers of the stomach,
  • The development of erosive gastritis,
  • Impaired renal function (urinary retention, increasing the concentration of urea and creatinine in the blood),
  • Acidosis.

Treatment of overdose is to remove the remnants of the drug from the body, for which it is necessary to make a gastric lavage and take some sorbent. This is followed by symptomatic therapy aimed at maintaining the functioning of vital organs and systems.

Interaction with other drugs

The simultaneous use of Ketorol with acetylsalicylic acid, calcium supplements, other NSAIDs (Ibuprofen, Nimesulide, Diclofenac, etc.), glucocorticosteroid hormones, ethyl alcohol and corticotropin increases the risk of developing ulcerative lesions of the digestive tract and gastrointestinal blood.

The use of Ketorol with drugs containing paracetamol or gold compounds increases the risk of side effects from the kidneys. Combined use with methotrexate increases the risk of liver and kidney damage. Therefore, if there is a need to use methotrexate with Ketorol, the dosage of the first drug should be reduced.

Probenecid increases the concentration of Ketorol in the blood and lengthens the period of its elimination from the body, therefore the combined use of these drugs is contraindicated. Also reduce the rate of removal of Ketorol from the body drugs that block tubular secretion of the kidneys. In turn, Ketorol causes an increase in the level of Nifedipine, Verapamil and lithium preparations in the blood.

When Ketorol is added to narcotic anesthetics, their dosage can be significantly reduced, which favorably affects the general condition of the person.

Ketorol enhances the effects of insulin and other drugs to lower blood sugar levels (hypoglycemic drugs), but reduces the severity of the diuretic effect of furosemide by 20% and means for lowering blood pressure.

Using Ketorol at the same time as the following medications can cause severe side effects:

  • Valproate - possible violation of platelet aggregation and the development of difficult to stop bleeding,
  • Non-depolarizing muscle relaxants (Pipekuroniy, Pankuronium, Tubocurarin, etc.) - the development of shortness of breath is possible,
  • Antiepileptic drugs (phenytoin, carbamazepine, etc.) - the frequency of epileptic seizures increases,
  • Antidepressants (fluoxetine, thiotiksin, alprazolam, etc.) - hallucinations may appear,
  • Pentoxifylline, cefoperazone, cefotetan, heparin, thrombolytics (drugs that increase the destruction of blood clots) and anticoagulants (drugs that reduce blood clots) - increases the risk of possible bleeding,
  • Angiotensin-converting enzyme inhibitors (Berlipril, Vazolapril, Enalapril, Captopril, etc.) - the risk of developing kidney disorders increases.

Solution for injection Ketorol can not be mixed in the same syringe with morphine, promethazine and hydroxyzine, because the chemical reaction between these substances precipitate, and they completely lose their therapeutic efficacy.

Use during pregnancy and breastfeeding

Tablets and injection Ketorol are contraindicated for use throughout pregnancy and breastfeeding. Pregnant women should choose other approved anesthetics such as Ibuprofen, Nurofen, No-Spa and others. If a nursing mother takes Ketorol, then you should transfer the child to artificial feeding for the entire period of treatment.

Ketorol gel can be used with caution during the first and second trimesters of pregnancy, that is, up to 27 weeks of gestation, inclusive. Caution is in careful prevention of possible accidental ingestion of the drug inside, for example, to lick the gel remaining on the lips after they have been rubbed unwashed after the application of the product, etc.

In the third trimester of pregnancy, that is, from week 28 and before delivery, gel Ketorol can not be used, because it can provoke perenashivanie or complications of labor activity.

Ketorol for toothache

With toothache, Ketorol is an excellent and effective drug that relieves discomfort quickly and permanently. The drug can be used both before the visit to the dentist, and after the performed manipulations, when the pain can persist for some time until the tissues heal.

If Ketorol is used to relieve toothache before visiting the dentist, then it should be remembered that the drug should not be taken for longer than 5 days, and it is not advisable to postpone the visit to the specialist, since any pain in the teeth indicates the need for their treatment or removal. Moreover, a long-term attempt to stop Ketorol pain can worsen the clinical situation, and where only tooth treatment was required, its removal may be necessary.

For toothache, Ketorol is optimally taken in pills, since this form is quite effective and convenient at the same time. Usually, in order to relieve pain, take 1 pill. The second pill can be taken no earlier than 4 hours. If after 4 hours the pain is still absent, then taking the next tablet of Ketorol should be postponed until the onset of pain again. During the day for the relief of toothache, you can take a maximum of 4 tablets.

Ketorol children

Ketorol gel can not be used in children under 12 years of age, and tablets and injection solution - under 15 years. Thus, the use of Ketorol in children in any dosage form is impossible.

The ban on the use of Ketorol for children is due to the fact that the drug can cause severe complications in babies, such as nephritis (inflammation of the kidneys), depression, hearing and visual impairment, allergic reactions, pulmonary edema, etc.

Therefore, for children it is necessary to choose other painkillers that have a milder effect than Ketorol and a low risk of developing serious side effects, such as, for example, Ibuprofen, Nimesulide, etc.
More about toothache

The composition and principle of operation

The active substance of Ketorol is Ketorolac, which belongs to the category of non-steroidal anti-inflammatory drugs (NSAIDs). It works by inhibiting the synthesis of prostaglandins, which causes its anti-inflammatory and analgesic effect. Ketorol (and other ketorolac-based drugs) is included in the group of essential drugs.

The exact composition depends on which medicinal form Ketorol is released: it can be a tablet, injection or gel (sometimes referred to as an ointment) for external use. The latter has the largest number of components:

  • Ketorolac 2%
  • propylene glycol,
  • dimethylsulfoxime,
  • ethanol,
  • glycerol,
  • tromethamine.

All these components are auxiliary, therefore they do not possess additional pharmacological properties, however, alcohol can have a drying effect on the skin, which requires caution in using Ketorol.

Tablets have a single concentration of the active substance - 10 mg each, in the package is 20 pieces. Lactose is present in their composition, as well as starch, silica, magic stearate, propylene glycol, cellulose. The tablets have an enteric shell of green color.

All 3 dosage forms with respect to the active components have the same composition, therefore, their working principle is identical: Ketorolac has anesthetic, anti-inflammatory and weak antipyretic effect through blocking cyclooxygenase, which prevents the development of the inflammatory process, and also suppresses pain. At the same time, Ketorol does not have a narcotic nature, therefore it does not affect the nervous system, it does not depress respiration.

However, while Ketorolac affects the chemical composition of blood, diluting it, and also reduces the rate of coagulation. Oral administration and intramuscular administration give the fastest result: after 60 or 30 minutes. respectively. The maximum concentration of ketorol in the blood will happen in 2 hours.

What does Ketorol help?

The main indication for the use of this drug is pain syndrome of any etiology - doctors prescribe Ketorol for headache, toothache, muscle, for discomfort caused by neuralgia. However, you need to understand what kind of dosage form is suitable for a particular situation.

  • If the pain is caused by injury or overload of the muscles, diseases of the musculoskeletal system (radiculitis, osteoarthritis, rheumatism, etc.), and also accompanies the person after surgery, then you should use the gel. It will work only locally, will give fewer side effects.
  • With monthly pain, Ketorol is recommended in tablet form, as with neuralgia, severe myalgia (over a large area), migraines, etc. Tablets are considered the most versatile option, but not the safest.
  • Intramuscular injections are given mainly in situations where oral administration is impossible or a very quick result is required: there can also be headache, toothache, muscle pain, joint pain. But often the doctor must give a prescription for the use of Ketorol solution.

Keep in mind that Ketorol, like all analgesics, only helps eliminate the symptom, but does not have a therapeutic effect, so it cannot be used on a permanent basis for a long time.

Instructions for use

Ketorol tablets for toothache, headache, etc. It is advisable to drink before meals so that the stomach is relatively empty, because otherwise the absorption of the active substance into the blood will slow down and the effect of the intake will appear later than it should. In this case, the tablets are not crushed, do not divide, do not chew - they are washed down with warm water in large quantities (100-150 ml).

  • The dosage for a single dose - 10 mg, for a day, you can drink up to 40 mg of ketorolac.
  • The maximum duration of continuous administration of Ketorol is 5 days. The remaining cases are reviewed with the doctor.

Intramuscular administration of Ketorol should be discussed with a specialist to select an individual dose: it is important to do with the minimum possible amount of the drug. Adults are prescribed mainly from 10 to 30 mg per time, the interval between injections is 6 hours. In old age (65 years and older), the dosage is reduced to 15 mg.

  • The maximum daily dose intramuscularly is 90 mg for adults and 60 mg for the elderly.

If necessary, the doctor combines Ketorol with other drugs: in particular, it is combined with saline, lidocaine, heparin, glucose, insulin - all of this is used for droppers. In this case, the transition between oral and injecting methods of using the drug should also be discussed with a doctor.

The gel Ketorol is the easiest to work with - the main thing is that it does not fall on the mucous and open wounds. Before treating the area affected by pain, it is necessary to wash it, remove moisture with a paper towel, and then distribute a small amount of gel with a rubbing motion. If necessary, this area is closed with a gauze bandage, but polyethylene and so on. Non-breathing materials are prohibited.

The gel is used up to 4 times a day, maintaining an interval of 4-6 hours between them. The duration of its use can be 10 days, unless other terms have been indicated by a doctor.

Summing up, it should be recalled that all NSAIDs have a lot of contraindications and side effects, so when using Ketorol, especially orally or intramuscularly, you need to strictly follow the dosage and try not to carry out long-term therapy. In addition, this drug can not be used in children, pregnant and nursing mothers, and should not be combined with other NSAIDs.

Perfilyeva Inna Yuryevna

Psychologist, Psychodramatist. Specialist from the website

I always took not ketorol, but ketans. It helped me a lot. It seems that ketorol is even stronger if I am not mistaken. The main thing is to measure everything to know.

I can not live without them, well, they still help nurofen

In general, these are analogues. The original drug ketonal. I accept it. Yes, it is quite strong, so I take it only if you can not stand the pain and never these days do not drink alcohol and heavy food, so as not to suffer the liver.
Oh yeah, you don’t need to drink it on an empty stomach!

I and ketorol saw, and ketonal. And in the pharmacy they advised that these days it is better to drink tempalgin (I take two tablets)

I and ketorol saw, and ketonal. And in the pharmacy they advised that these days it is better to drink tempalgin (I take two tablets)

If the pain is so strong and the pentalgins-nurofenes do not help, then drink ketorol or ketans, you can. It is the same. Although they are very energetic, if the means easier to help, then they are better.
Although I never in my life saw these ketorols-ketanes, and Pentalgin saw only 3 times in my life from my head, when I was sick, but I had to go somewhere and be alert, and in general the periods are painless, and if That is tolerated, it is possible and without pills, if there is an opportunity to lie down at home. So I can't say for sure about these pills.

I drink ketorol, but only one pill on the first critical day, but no-shpa helps me. So I accept that at the moment there is in the home first-aid kit. If you don’t need to go anywhere this day, I’m doing without pills.

I accept, more than two pieces per day is undesirable, it affects the liver. And if you are unwell, then with caution. Although honestly, I did not feel the effect after the operation on the liver.

I after the use of ketorol monthly inhibit

I after the use of ketorol monthly inhibit

I also took Ketorol. I had severe bleeding for 1-2 days. And after the pill there was nothing at all. And then again, 5-6 days, my periods started.

That is why the skill and so began to slow down the monthly. And before that, everything went normally for 7 days. Now 2-3 days go, the day does not go, then they go again. generally unstable. All, no longer accept with monthly ketorol

What to do if I have eaten two toblets of ketorol; because of this, I had no mesic 2 mesica how to be

I, too, had recently been drinking Ketorol, the tooth was very sick. tooth cured, ketorol no longer drink. Saw for 5-6 days, 2 tablets per day. Now the delay is already 8 days .. I do not know what to do, can anyone advise?

there were severe pains, almost to a swoon, I called an ambulance, they gave me ketorol intravenously, and advised him to take it for such pains. the next day the monthly ended, even though it was 2 day of monthly :)

I, too, had recently been drinking Ketorol, the tooth was very sick. tooth cured, ketorol no longer drink. Saw for 5-6 days, 2 tablets per day. Now the delay is already 8 days .. I do not know what to do, can anyone advise?

I am only saving with these pills. I have terrible pains during menstruation and other pills do not help. How much can I drink them a day?

I have been drinking ketarol-kutan-ketarolak for several years, it is effective, but you should not drink for more than 2-3 days, the feeling of heaviness in the whole body. I was also helped by noshpa + analgin, relieves cramps and pain. Alas, I can not endure pain without medication, the pills last 3-6 hours, half an hour to work.

Spazgan drink or baralgi 2 tablets. мне кажется они более безопасные! От кеторола желудок и кишечник болит! У меня так случилось! Лечила одно-другое заболело!

я тоже слышала что нельзя принимать кетарол.только когда без выходное положение.но мне они помогает.и никаких задержек нет..наоборот на неделю вперед идут

I also drink ketorol, but on the first day and 1 time, before menstruation was 7 days now 5 years already 3 days and everything is not so abundant, I like it.

I and ketorol saw, and ketonal. And in the pharmacy they advised that these days it is better to drink tempalgin (I take two tablets)

Guys, can I drink Nurofen updated with ketarol?

When I saw Pentalgin-p. These were the most beautiful pills that relieved me of all the pain in my stomach, literally a couple of minutes after it was taken. Then, at the pharmacy, they stopped issuing them without a doctor's prescription, pharmacists said that there was a narcotic substance in it, which relieves pain, and you cannot take it without a doctor’s instructions. For a long time she suffered, for every month she used everything new, then ketonol, then no-spa, then tempalgin. nothing helped at all, I get sick so much during menstruation that sometimes I dream to die and stop suffering. And once I decided to buy Ketorol, I take 2 pills, after 10-15 minutes the pain goes away. I advise everyone. Good stuff.

Only he helps me! No other drugs help. Pain terrible, even climb on the wall. The pain passes exactly at 12 o'clock. But these pills are very strong.

When I saw Pentalgin-p. These were the most beautiful pills that relieved me of all the pain in my stomach, literally a couple of minutes after it was taken. Then, at the pharmacy, they stopped issuing them without a doctor's prescription, pharmacists said that there was a narcotic substance in it, which relieves pain, and you cannot take it without a doctor’s instructions. For a long time she suffered, for every month she used everything new, then ketonol, then no-spa, then tempalgin. nothing helped at all, I get sick so much during menstruation that sometimes I dream to die and stop suffering. And once I decided to buy Ketorol, I take 2 pills, after 10-15 minutes the pain goes away. I advise everyone. Good stuff.

I drink ketorol, but only one pill on the first critical day, but no-shpa helps me. So I accept that at the moment there is in the home first-aid kit. If you don’t need to go anywhere this day, I’m doing without pills.

I'm 18. I drink ketorol on the day 2-3 tablets, and even the first days of menstruation 2-3 days in a row. before that, she had a serious illness and drank 20 tablets per day (other pills). I think my liver will soon be felt. but I don’t manage without ketorol, this is my savior. By the way, he slows down the monthly, t. *****. at the rate does not come, a little bit. this extends them, if someone has 3-4 days, I have 5-6-7 days of menstruation. but always come on time.

and I, too, inhibit menstruation from ketorol

After how much does ketor start to act?

Read the instructions. Ketorol reduces the production of prostaglandin, and prostaglandin is just because of what menstruation and come. This hormone causes the uterus to contract and reject unnecessary endometrium. Drink ketorol - prostaglandin is produced less - less uterine contractions - less discharge. Therefore, inhibit monthly. But the uterus must be cleansed.

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Ketorol - injections

Regardless of the cause of pain, in many cases non-steroidal anti-inflammatory drugs are the first-line treatment. Today, drugs of this group are represented by a wide range, and the choice of the most optimal variant takes into account the intensity of the pain syndrome, the presence of concomitant diseases and some other factors. Consider the cases in which the use of one of these agents, Ketorol, is recommended in the form of injections.

The composition and properties of the drug Ketorol for injections

Ketorol for injections is available in ampoules containing 1 ml of solution. The active ingredient of the drug is Ketorolac. Solution auxiliary substances:

  • sodium chloride,
  • ethanol,
  • water,
  • sodium hydroxide, etc.

    The drug has the following effect:

  • weak febrifuge
  • anti-inflammatory,
  • pronounced anesthetic.

    The onset of analgesic action is observed already half an hour after the administration of Ketorol in the form of an injection. The maximum effect is noted in 1-2 hours, and the duration of the therapeutic effect is about 5 hours.

    Indications for use Ketorol

    The injection form of the drug Ketorol is recommended for use with an average and severe pain syndrome of any localization to obtain a rapid analgesic effect. This form of the drug is prescribed in cases where taking Ketorol tablets is impossible. It is advisable to use Ketorol injections in the treatment of acute conditions, and not for the treatment of chronic pain syndromes.

    So, Ketorol shots can be used for:

  • postoperative pain,
  • post-traumatic pains,
  • pains associated with neoplastic diseases
  • muscle and joint pain,
  • rheumatic diseases
  • migraines,
  • renal and hepatic colic,
  • thermal burns, etc.

    Ketorol Injection Dosage

    Ketorol painkillers injections are performed intramuscularly, less often - intravenously. As a rule, the solution is injected into the outer upper third of the thigh, shoulder, buttock. It is necessary to inject deep into the muscle, slowly.

    The dosage of the drug is chosen by the attending physician individually, but you should always begin therapy with the minimum dose, and then to orient depending on the patient's response and the effect achieved. For patients younger than 65 years of age, a single dose of Ketorol can range from 10 to 30 mg. Injections can be repeated every 4 to 6 hours, while the maximum daily dose should not be higher than 30 ml.

    Side effects of Ketorol pricks

    When treating Ketorol in the form of injections, side effects from various organs and systems are possible, namely:

  • insomnia,
  • urine retention, etc.

    Ketorol injections and alcohol

    Injections of this drug are not compatible with the intake of alcohol-containing beverages. Drinking alcohol during treatment with Ketorol not only reduces the effectiveness of the drug (the duration of action decreases), but also increases the risk of side effects. Therefore, in the period of treatment should refrain from taking alcohol.

    Contraindications to the appointment of injections Ketorol

    You can not use the drug if there are:

  • dehydration,
  • erosion and ulcers in the digestive tract in the acute phase,
  • liver and kidney failure
  • hemorrhagic stroke,
  • pregnancy, lactation,
  • increased risk of bleeding,

  • reduced blood clotting,
  • individual intolerance to the components of the drug.
  • What do Ketorol shots help with and how to put them: instructions, reviews

    Severe pain can strike a person unexpectedly or be a symptom of a serious illness that should be urgently treated. In most cases, doctors recommend removing pain, using special preparations. One of these tools are Ketorol injections.

    The drug Ketorol belongs to the group of nonsteroidal anti-inflammatory drugs with a pronounced analgesic (analgesic) effect.

    Additionally, the tool is prescribed to people who have undergone surgery, including tooth extraction.

    The injection of the drug Ketorol is intramuscular.

    The composition of ampoules

    Injection for intramuscular injection is a homogeneous liquid composition, which visually can be transparent, yellowish or translucent, colorless. There are no foreign particles or sediment.

    The drug is produced in ampoules made of dark glass. Cardboard packaging, each with 10 ampoules of 1 mg each. The syringe is made of plastic, compact, designed for a volume of 0.5 -1 mg (per 1 vial of the drug). Composition of Ketorol:

  • Ketorolac is an active substance
  • sodium compounds

  • purified water (without impurities, designed specifically for injection),
  • alcohol (ethanol),
  • propylene glycol,
  • octoxynol,
  • disodium edetat.

    Pharmacological profile

    The main active substance in the preparation Ketorol is the substance Ketorolac - 30 ml of this substance are contained in 1 ml of solution. Its action consists in the rapid inhibition of a substance that is responsible for pain - prostaglandin. As a result, the biosynthetic processes that lead to its formation in the human body, fade out, and then completely cease.

    Together with the pain syndrome, inflammatory processes that often accompany injuries of the joints and ligaments disappear.

    The analgesic effect of Ketorol in the form of an injection occurs:

  • with weak the severity of pain after 20-40 minutes after drug administration,
  • with a moderate degree manifestations - in 30-60 minutes,
  • severe pain will disappear in 1-2 hours.

    The therapeutic effect lasts for a long period of time - for 3-7 hours.

    Ketorol in the form of a solution for injection by intramuscular injection is well absorbed from the gastrointestinal tract. To increase the effectiveness of the drug, it is recommended to stop eating fatty and heavy foods one hour before the injection, so you can achieve a quick improvement.

    The binding of constituents with plasma proteins reaches 99%. Bioavailability of the drug - 80 - 93%, depending on the individual characteristics of the patient. Absorption is quick and complete. 55% of the drug entered the body is processed by the liver.

    As a result of these processes, metabolites are formed which, by their nature, are pharmacologically inactive. The main substance obtained as a result of ongoing processes are glucuronides. They are excreted by the kidneys by 91%, as well as through the intestines.

    The drug penetrates into breast milk, therefore, during the period of breastfeeding, you should observe precautions - after taking the drug it is recommended to refrain from the lactation process for 2-4 hours.

    The effect of an intramuscular injection is based on a gradual decrease in COX activity.

    It is not addictive, does not affect opioid receptors, does not violate breathing, but allows you to reduce or significantly alleviate pain and stiffness associated with them.

  • greatly reduce the likelihood of edema at the site of injury or reduce the already formed ones,
  • reduce pain that occurs in joints and muscles,
  • allow you to increase the intensity of movements.


    Most drugs have restrictions on use, which should be carefully examined before embarking on treatment. This is especially true for those people who have not been diagnosed. Contraindications to the use of Ketorol:

  • bronchial asthma,
  • polyposis,
  • "Aspirin" asthma,
  • intolerance to the components of the drug,
  • pregnancy,
  • lactation,
  • age restrictions (up to 16 and after 65 years),
  • edematous syndrome of varying severity,
  • hypertension,
  • hemophilia,
  • hemorrhagic stroke and diathesis,
  • diabetes mellitus (all types),
  • cholestasis
  • bronchospasm
  • the simultaneous reception of other, similar in effect drugs
  • tissue or blood infection processes,
  • artery disease
  • ulcerative colitis,
  • Crohn's disease,
  • lupus erythematosus,
  • risk of bleeding,
  • bad habits (smoking, problems with alcohol),
  • hepatitis (active)
  • allergic reactions or component intolerance,
  • severe renal failure
  • liver disease,
  • problems with the heart and blood vessels
  • erosive damage to the digestive tract,
  • peptic ulcer disease.

    In order to protect yourself and not get health complications during treatment and use of the drug, you must first complete a thorough examination by a specialist, as in some cases it is extremely important to obtain test data.

    From reviews of doctors and patients

    Reviews of practicing doctors, as well as their patients, on injections of the anesthetic Ketorol can be found below.

    The drug was used after the removal of a wisdom tooth - after 2 days I forgot about the pain. I was pleased.Sergey, 34

    Ketorol I use injections at attacks of a radiculitis. they happen from time to time. The tool helps stably well, the only thing that bothers is a headache within 20-30 minutes after drug administration.

    According to my medical practice, I can say - do not change the dosage voluntarily, and at the first sign of discomfort after the Ketorol injection, contact your doctor.

    Ketorol (tablets, gel, injections) - instructions for use, analogues, reviews, price

    Ketorol is a very powerful non-narcotic pain medication with anti-inflammatory activity and a moderate antipyretic effect. However, the main effect of Ketorol - analgesic (analgesic). Due to its powerful analgesic effect, the drug is ideal for relieving moderate or severe pain syndrome, especially associated with traumatic tissue damage.

    Influence on ability to operate mechanisms

    The effect on the ability to control mechanisms is noted only in tablets and injection solution. Gel Ketorol does not affect the ability to control mechanisms. Since Ketorol tablets and solutions can provoke side effects from the central nervous system (drowsiness, dizziness, headaches, etc.), they significantly impair a person’s ability to control mechanisms. Therefore, against the background of the use of Ketorol solution or tablets, it is necessary to avoid activities that require a high reaction rate and concentration.

    Side effects of the drug Ketorol

    The side effects of the tablets and the solution for injection are the same, but they are somewhat different from those of the gel Ketorol. The entire set of side effects of tablets and Ketorol solution is shown in the table.

    Ketorol is an analgesic drug with anti-inflammatory and antipyretic effects.

    Ketorol is the active substance of ketorolac, which, by inhibiting the activity of the cyclooxygenase enzyme, contributes to the inhibition of the biosynthesis of prostaglandins, which are modulators of inflammation, thermoregulation and pain sensitivity.

    The analgesic effect of Ketorol can be observed already half an hour after the injection, and the maximum effect - in 1-2 hours.

    Ketorol instructions are recommended to be prescribed for moderate to severe pain: muscle and back pain, pain in joints, sprain, sprains, postoperative pain, neuralgia, cancer, radiculitis, toothache, migraine, burns, etc.

    The composition and medicinal effect of tablets Ketorol

    Before considering the question of whether Ketorol tablets can be drunk with severe lower abdominal pain during menstruation, we will briefly review the main features of the drug.

    Ketorol is a non-steroidal anti-inflammatory agent containing the active substance Ketorolac. Available in the form of tablets for oral administration and solution for injection. The drug has a pronounced analgesic effect, due to which it has gained wide popularity among women suffering from severe abdominal pain during menstruation.

    Can I take Ketorol tablets for menstrual pain?

    Ketorol can be drunk with menstrual pains of low or medium intensity. But tablets are allowed to take a short course, and only with strict observance of the instructions attached to the medicine.

    Ketorol to eliminate severe pain in the lower abdomen during menstruation can only be drunk from the age of 16. Young girls who have not reached this age are advised to take Paracetamol or Nurofen as a painkiller.

    Does it help or not?

    Does Ketorol help with severe lower abdominal pain during the menstruation period? If you believe the numerous reviews of patients, the drug is highly effective, and quickly eliminates pain. The effect of the drug begins already after 20-30 minutes after taking the pill.

    But, if the medication does not help, do not increase the dosage - this can only harm health. In this case, you should seek help from a gynecologist, who will select a more effective painkiller.

    Method of use Ketorol

    The method of use of the drug depends on the form of its release. So, with too much pain accompanying the period of menstruation, Ketorol tablets do not always help. Moreover, they can harm the gastrointestinal tract, and the fact that their action occurs only half an hour after administration does not suit all patients. In this case, it is better to resort to the use of the solution for injection.

    Let us consider in more detail the rules for applying Ketorol in different forms of release to eliminate abdominal pain during menstruation.

    Ketorol with severe pain in the lower abdomen during menstruation, you must take 1 tablet a maximum of 4 times a day. The effect of the drug lasts about 4-6 hours, but this is purely individual. If the pain appears 1-2 hours after taking the Ketorol tablet, you should not drink it again. The interval between doses must be at least 4 hours. You can continue therapy for no longer than 5 days.

    Injection solution

    Solution for intramuscular injections Ketorol has a faster effect than the tablet form of the drug. But an obstacle to its use is that not every patient will be able to independently deliver an injection at home. In addition, there is not always a person with a medical education who is ready to perform the manipulation.

    If a woman does decide to use exactly this form of Ketorol, she should carefully consider the dosing regimen of the injection solution. With moderate pain during menstruation, it is recommended to inject 30 mg of the drug once or every 6 hours (depending on the duration of the medication). If the pain syndrome is too strong, 60 mg (2 ml) of the drug can be administered at once.

    Possible side effects

    Side effects when taking or intramuscular use of Ketorol to reduce pain during menstruation may occur:

    • stomach pains
    • diarrhea,
    • flatulence
    • vomiting
    • constipation
    • nausea
    • allergic rhinitis,
    • headaches
    • dizziness
    • sleepiness
    • skin rashes,
    • urticaria,
    • peeling of the epidermis,
    • itching on the body, etc.

    These are the most common side effects that the medication in question may provoke. They appear in rare cases, and are a manifestation of the body's hypersensitivity reaction.

    Not always side effects should be a reason for refusing pain relief during menstruation with the help of this medication.

    But if they appear regularly, after each use of these pills, you should consult a doctor. Use of the drug in such circumstances will have to stop.

    First Aid for overdose

    First of all, it is necessary to cancel the use of the drug. Obligatory action is clipping, but since it is not recommended to do it during menstruation, you can get by with the use of adsorbents.

    If necessary, symptomatic treatment is carried out, aimed at maintaining the vital functions of the body. But it should be borne in mind that dialysis in this case will not be effective.

    What can replace Ketorol?

    If it is not possible to take Ketorol for pains provoked by menstruation, you can purchase a substitute for it. The most effective and best analogues of the considered drugs are:

    1. Ketanov. The active substance is ketorolac. Available in the form of tablets for oral administration. The cost of 1 package of medicine (20 pcs.) Is 70 rubles.
    2. Ketorolac. Tablets for oral use, containing the active substance with the same name. Estimated cost - 40 rubles for 10 pcs.
    3. Ketolack Another drug based on ketorolaka. Price - from 25 rubles for 10 pieces.

    It should be borne in mind that all these analogues of Ketorol contain the same active substance. Because of this, women with individual intolerance to Ketorolak are not recommended to take them.

    Ketorol is positioned as a highly effective tool designed to eliminate pain. It can be taken during menstruation, but it is important to fully adhere to the instructions that are attached to it. Only accurate adherence to all recommendations regarding the administration of pills will make therapy as safe as possible!

    Ketorol with toothaches - instructions for use!

    Taking Ketorol with a toothache is one of the most effective and effective ways to combat this problem; it is popular due to its strong analgesic effect, which allows you to quickly neutralize the painful symptoms.

    Ketorol is a nonsteroidal agent that has a strong anti-inflammatory effect. The drug is considered one of the strongest non-narcotic painkillers.

    Release it in the form of tablets, solution for injection and gel for external application. Ketorol is very similar to ketans by its main characteristics (the same active ingredient is included in the preparations).

    It begins to affect the body after only 15-20 minutes after ingestion, and the peak of its action drops to 40-50 minutes from the time of use, and the effect lasts for about 5 hours. For toothache, use the drug in the form of tablets. In pharmacies, it is released on prescription.

    When taken properly, cases of side effects are very rare, as are cases of lack of a positive result after consumption. However, doctors note that these funds should be taken only with very strong pain before arriving at the dental office.

    Composition and effect on the body

    The main active ingredient of ketorol is ketorolac, which has a bright anti-inflammatory effect, so it helps to cope with strong pain.

    Damaged areas on the teeth are anesthetized with the help of an agent, but this does not mean that the pathological processes stop. They continue to flow with the same intensity, but the person stops feeling pain. For such a strong and fast action, ketorol is often compared to drugs.

    The drug temporarily relieves the symptoms of the disease and in no way treats it. Some patients, due to the use of strong painkillers for a long time, did not turn to specialists. As a result, the affected teeth were completely destroyed, which led to their loss and costly treatment.

    Ketorol does not cause dependence and rarely gives side effects. For a person without complex pathologies in the body, the medicine is safe, but this does not mean that you can abuse it. In any case, it is important to take it after a careful study of the instructions, consultation with a specialist.

    How to take Ketorol with toothache?

    It is recommended to take the medicine when the painful sensations are characterized by severe urgency. With chronic pain, its use will not bring the desired effect.

    The less often you use Ketorol, the more positive it affects the body, one pill will be enough to relieve the pain before the visit to the doctor, if this fails, you can re-take the drug.

  • you should not take more than four tablets of ketorol per day (and the intervals between doses must be from 4 hours),
  • taking painkiller should not exceed 5 days,
  • when taking the pill you need to drink plenty of water
  • the presence in the stomach of too high amounts of fat can adversely affect the action of ketorol.

    Separately, I would like to talk about the use of the drug in the form of a solution for injection, to relieve toothache is rarely used.

  • total dose per day should not exceed 90 milligrams,
  • one-time person can enter from 15 to 30 mg of medication,
  • the next injection should occur no earlier than 5 hours after the previous input.

    This form of consumption allows him to act much faster, but a person without special education is recommended to use pills.

    Additional questions

    The price may vary in each specific pharmacy. As a rule, it is in the range of 40 to 60 rubles per pack of tablets (20 pieces). The price of the solution is from 150 to 180 rubles for 10 ampoules of 30 milliliters each.

    Ketans or ketorolac, as they are closest in action to ketorol. You can also use a dolak or nise.

    > What is better than ketorol or nise?

    Both have a similar analgesic effect, but Nise gives a stronger anti-inflammatory effect. On the other hand, it is more expensive than ketorol - you will have to pay between 150 and 200 rubles for a package with 20 tablets.

    With an overdose of ketorol, patients observe severe abdominal pain, disorders in the work of the kidneys, erosive processes in the gastrointestinal tract. Need to immediately go to the hospital.

    > Which is stronger: ketorol or ketonal?

    The main active ingredient of ketorol is ketorolac, and ketonal is ketoprofen. The effectiveness of each of them depends on the characteristics of the patient. It is believed that they have approximately the same analgesic effect.

    > Can I take for monthly pain?

    Yes, it really helps with monthly pain, but it is recommended to use it only in extreme cases. As a rule, ketorol can be replaced with tempalgin, which is better suited to alleviate female pain.

    What helps “Ketorol”

    "Ketorol", from which helps this non-narcotic action of anesthetic medicine? The drug creates a powerful analgesic effect, has moderate antipyretic properties. "Ketorol" well helps with strong and moderate pain, especially caused by injuries and tissue damage.

    Composition and varieties

    Available in the form of round biconvex green tablets containing the active element - Ketorolaka in a volume of 10 mg. The solution “Ketorol” is also used, which helps it faster and is used in more complex cases. Injections are intended for intramuscular and intravenous administration. A 1 ml ampoule contains 30 mg of ketorolac.

    Popular and gel with 2% content of the active ingredient. The preparation contains additional substances, the list of which depends on its variety. Thus, Ketorol tablets contain: starch, lactose, magnesium stearate, sodium carboxymethyl starch. The solution for injection includes: octoxynol, ethanol, propylene glycol, hydroxide and sodium chloride.


    The mechanism of action of the drug is to delay the synthesis of cyclooxygenase - a special enzyme substance that converts arachidonic acid into prostaglandins, which cause pain, inflammation and fever. By suspending the formation of these dangerous enzymes, the medicine Ketorol exhibits its antipyretic, anti-inflammatory and analgesic properties. The drug is most pronounced analgesic properties, so the main scope of its use are pain symptoms of various etiologies.

    The drug is not a narcotic analgesic, therefore it does not adversely affect the central nervous system, it does not inhibit respiration, does not cause urine retention, bradycardia, or increased pressure. It is also known about the anti-aggregative properties of the drug, which is able to thin the blood. The tool reduces the activity of the coagulation system.

    The drug "Ketorol": from what helps

    The drug allows you to remove the symptoms of the disease, without affecting its cause. Tablets "Ketorol" help:

  • from toothache or headache,
  • with rheumatic diseases,
  • painful periods,
  • arthralgia,
  • sprains,
  • after surgery,
  • sprains
  • pains during oncology,
  • radiculopathy.

    When is gel prescribed?

    The ointment is used topically to reduce the inflammatory process and pain when:

  • radiculitis
  • bursitis,
  • epicondylitis,
  • neuralgia,
  • rheumatism,
  • damage to soft tissue and ligaments,
  • injuries and bruises
  • myalgia
  • bluish
  • tendinitis.

    Drug "Ketorol": instructions for use

    Tablets are taken orally after meals. Depending on the strength of the pain, the medication can be used once and repeatedly. Single use includes 1 tablet, with repeated use of the tool is used in the same dosage up to 4 times a day. It is forbidden to drink the product for more than 5 days in a row.

    Injections to patients under 65 are given every 4 hours, deeply introducing into the muscle tissue. Perhaps a single application of the solution to 30 mg. The maximum daily volume should not exceed 90 mg. Patients after 65 years, the dosage is reduced by half to 15 mg once.

    Gel "Ketrol" instructions for use prescribed to apply to clean, dry skin, which should not be signs of violations of the integrity of the cover. A thin layer of ointment is treated with disease areas, rubbing the medicine in soft circular motions up to 4 times a day. The time interval between applications should not be less than 4 hours. Without medical prescription, the drug can be used up to 10 days.

    Side effects

    The use of the solution and injections can cause such negative reactions in the patient as:

  • fever, blurred vision, diarrhea,
  • bronchospasm, acute kidney failure, increased sweating,
  • stomach pain, Lyell's syndrome, vomiting or nausea,
  • increased pressure, nephritis, Stevens-Johnson syndrome, constipation,
  • fainting itching, flatulence, pulmonary edema,
  • urticaria, stomatitis, leukopenia, discoloration of the face,
  • nausea, eosinophilia, skin rash, heartburn,
  • anemia, edema, urticaria, difficulty breathing,
  • low back pain, headache, hyperactivity, depression.

    It is forbidden to use the medication inside and make injections with:

  • hypersensitivity to the composition,
  • active bleeding,
  • bronchial asthma,
  • hyperkalemia,
  • polypous rhinosinusitis,
  • renal failure
  • hemophilia
  • erosions and ulcers of the mucous membranes of the gastrointestinal system,
  • disorders and diseases of the liver,
  • intestinal pathologies occurring in acute form,
  • heart failure
  • children under 16 years old
  • during pregnancy and breastfeeding.

    Analogs and price

    Drugs like Ketokam, Diclofenac, Adolor, Ketorolac, Vatorlak, Ketalgin, Ketanov, Ortofen, Ketofril, Dolak, Dolomin, Voltaren "," Indometacin ". You can buy Ketorol tablets, the price of which starts from 45 rubles, without a prescription at the pharmacy. For 10 injections, 3% will have to be given - 125, for a 30 g gel - 195 rubles.

    Opinions of patients and doctors

    In the bulk of the patients about all the varieties of the drug "Ketorol", the reviews leave positive. A quick effect is noted after taking the pills: after half an hour, a toothache or a headache disappears, relief is observed in the muscles and back. The effect of the drug lasts for 6 hours.

    What swing side effects, the patients say that, subject to the instructions for use, negative reactions are practically not observed. Negative reviews are associated with multiple contraindications and the inability to use the drug for a long period.

    Read the instructions for the use of analogues:

    The composition of the tablets: ketorolac (10 mg / tab.), MCC, lactose, corn starch, colloidal silicon dioxide, Mg stearate, carboxymethyl starch Na (type A).

    The composition of the film shell includes: hypromellose, propylene glycol (additive E1520), titanium dioxide, brilliant blue (22%) and quinoline yellow (78%) - green olive.

    The composition of the solution: ketorolac (30 mg per milliliter), octoxynol, EDTA, Na chloride, ethanol, propylene glycol (additive E1520), Na hydroxide, water d / and.

    The composition of the gel: ketorolac (20 mg per gram of gel), propylene glycol (additive E1520), dimethyl sulfoxide, carbomer 974P, methyl and propyl parahydroxybenzoate Na, tromethamine (trometamol), Drimon Indus flavoring, ethanol, glycerol, purified water.


    The drug is powerfulanalgesic with anti-inflammatory properties and moderately severe antipyretic activity .

    The mechanism of its action is associated with the ability to indiscriminately suppress the activity of the enzyme COX 1 and 2, mainly in peripheral tissues. As a result, the biosynthesis of Pg - modulators of thermoregulation, pain sensitivity and inflammation slows down.

    Ketorolac does not affect opiate receptors, does not possess anxiolytic and sedative effects, does not inhibit respiration, does not lead to the development of drug dependence.

    The analgesic effect of the drug in comparison with analogues is more pronounced. The effect of its use is comparable to analgesic effect of morphine .

    After insertion into the muscle and ingestion, the pain begins to decrease, respectively, after 0.5 and 1 hour. To achieve the maximum effect, 60 to 120 minutes are needed.


    Absorption in the alimentary canal when ingested is fast. Tarmac after taking an empty stomach 1 tablet - 40 minutes.

    Fatty food reduces Smah of blood with a simultaneous increase in TSmah up to 1 hour and 40 minutes.

    99% of the dose taken is in a state associated with plasma proteins. With hypoalbuminemia, the concentration of free substance in the blood increases.

    One hundred percent bioavailability (regardless of the method of drug administration).

    When administered parenterally, the substance is absorbed quickly and completely.

    Equilibrium concentration of Css with the introduction of Ketorol in / in or in / m at a dose of 120 mg / day. (4 injections of 30 mg) and when taken orally at a dose of 40 mg / day. (1 tab. in 4 doses) is achieved after 24 hours. The highest values ​​of this indicator are noted with the parenteral administration of 1 ml of solution 4 p. / Day.

    The substance enters the breast milk: when taken by a nursing woman 1 tablet TSmah Ketorolaka in milk - 2 hours.

    More than 50% entered ketorolaka biotransformed in the liver to form pharmacologically inactive metabolites . The substance is mainly excreted in the form of glucuronic metabolites and p-hydroxyketorolac. 91% принятой дозы экскретируется почками, 6% — с содержимым кишечника.

    У пациентов со здоровыми почками период полуэлиминации в среднем составляет 5.3 часа.

    У пожилых людей Т1/2 удлиняется, у молодых укорачивается.

    Функциональное состояние печени не влияет на фармакокинетику препарата. With kidney damage, at which plasma concentration creatinine is 19-50 mg / l, the half-elimination period is extended to 10.3-10.8 hours, if renal failure more pronounced this figure exceeds 13.6 hours.

    Ketorol tablets: what does the tablet form of the drug help?

    The drug helps to reduce moderate / severe pain and inflammation, but does not affect the progression of the disease.

    Tablets are effective for toothache. at headache . for pain that occurs during menstruation, after injury, in the postoperative and postpartum periods, on the background of oncological diseases, with damage to peripheral nerves, with radiculopathy. arthralgia. myalgia. sprains, sprains, rheumatic diseases.

    What does the medicine help with injections?

    Ketorol in ampoules, as well as the tablet form of the drug, is used to relieve pain of medium and strong intensity.

    Parenteral administration of the drug is preferable in situations where it is necessary to quickly relieve the pain, and also if the patient cannot take it inside (for example, when peptic ulcer or because of the gag reflex).

    Indications for use Ketorola: what is used gel?

    Topical application of the gel helps to reduce pain and inflammation with:

    Contraindications for parenteral administration and oral administration of Ketorol:

  • hypersensitivity to the components of the solution / tablets,
  • full or partial combination of clinical manifestations aspirin bronchial asthma (intolerance to NSAIDs, asthma attacks, polypous rhinosinusitis ),
  • the presence of erosions and ulcers in the mucous membrane of the upper GI tract,
  • active phase bleeding (gastrointestinal, cerebrovascular or other),
  • aggravated inflammatory bowel disease,
  • hemophilia and other pathologies of the hemostatic system,
  • terminal stage of development heart failure (decompensated CH),
  • functional disorders or active course of liver disease,
  • confirmed hyperkalemia ,
  • the postoperative period after CABG
  • renal failure. at which concentration creatinine does not exceed 30 ml / min, progressive kidney disease ,
  • pregnancy . childbirth lactation ,
  • age up to 16 years.

  • stagnant heart failure ,
  • bronchial asthma (BA),
  • Ischemic heart disease ,
  • hypersensitivity to NSAIDs,
  • pathological dis- or hyperlipidemia ,
  • cerebrovascular pathology ,
  • arterial hypertension ,
  • kidney damage at which concentration creatinine below 60 ml / min
  • sepsis ,
  • cholestasis ,
  • edematous syndrome,
  • diabetes ,
  • SLE
  • chronic obliterating diseases of lower limb arteries,
  • treatment with other NSAIDs,anticoagulants ,antiplatelet agents. SSRIs, oral GCS,
  • ulcer lesion of the digestive canal in history
  • smoking,
  • advanced age (from 65 years),
  • alcohol abuse
  • severe somatic diseases.

    External use of Ketorol is contraindicated in case of hypersensitivity to any of the components of the gel, aspirin BA. eczema. weeping dermatitis. after the 27th week of pregnancy and in the period lactation . The gel is not intended for the treatment of open wounds and infected abrasions. Adolescents prescribed from the age of sixteen.

    With caution, Ketorol gel should be applied whenhepatic porphyria (at the stage of exacerbation of the disease), severe hepatic / renal failure. CHF, BA, in pregnant women (in the 1st and 2nd trimesters) and in the elderly.

    Side effects

    More than 3% of patients with parenteral administration and oral administration of Ketorol appear:

    Somewhat less (1-3% of patients) were recorded:

    Rare side effects that occur in less than 1% of patients:

  • nausea,
  • the formation of erosions on the gastrointestinal mucosa or its ulceration (including perforation and / or bleeding, symptoms of which are burning, pain and spasm in the epigastric region, bloody vomiting (coffee grounds) melena, heartburn . nausea, etc.),
  • hepatomegaly ,
  • hepatitis ,
  • PZhZh acute inflammation,
  • Arrester,
  • cholestatic jaundice ,
  • back pain (sometimes accompanied by azotemia and / or hematuria ),
  • HUS, which appears dominant in the clinical picture renal failure. and hemolytic anemia and thrombocytopenia ,
  • change in urine volume (decrease or increase),
  • frequent urination,
  • kidney edema,
  • nephritis ,
  • hearing losstinnitus ,
  • visual impairment (blurred perception of visual images),
  • rhinitis . bronchospasm. laryngeal edema
  • aseptic meningitis ,
  • hyperactivity (anxiety, mood variability),
  • depression,
  • mental disorders,
  • hallucinations ,
  • sudden loss of consciousness
  • edema lightweight
  • swelling of the tongue
  • leukopenia. eosinophilia. anemia ,
  • bleeding (from the lower gastrointestinal tract, nose, postoperative wound),
  • exfoliative dermatitis ,
  • Lyell's syndrome. malignant exudative erythema. hives ,
  • anaphylactoid reactions or anaphylaxis ,
  • fever .

    When applied externally ketorolaka peeling of the skin at the site of application of the gel, hives . itch .

    When applying the drug to a large area of ​​the body, the likelihood of systemic effects is not excluded, including:

    Ketorol tablets: instructions for use

    The medicine is taken orally from 1 to 4 p. / Day. Single dose - one tablet. The highest daily dose is four tablets. Treatment should last no more than 5 days in a row.

    When switching from parenteral administration to a tablet form of the drug, the total dose of the drug in the form of tablets and solution on the day of transfer should not exceed 90 mg / day. if the patient is younger than 65 years, and 60 mg / day. if the patient is older than the specified age.

    The upper limit of the daily dose of Ketorol tablets in the day of the transition - 30 mg.

    Ketorol injections: instructions for use

    The solution is intended for intramuscular and intravenous administration. To use the drug in this dosage form is necessary in the minimum effective doses.

    If necessary, Ketorol can be used in combination with narcotic analgesics (the latter is prescribed in reduced doses).

    Patients younger than 65 years old, provided that their weight is more than 50 kg, no more than 2 ml of solution can be injected once into the muscle (taking into account oral administration). As a rule, for the relief of pain, 1 ml of Ketorol is administered in ampoules every six hours.

    Ketorol in / in injected 1 ml so that the volume injected for five days of the drug does not exceed 15 single doses.

    Patients whose weight is less than 50 kg, as well as patients with ESRD, a single dose with the introduction of Ketorol into the muscle should not exceed 1 ml of solution (taking into account oral administration).

    As a rule, the drug is administered in 0.5 ml so that in five days the patient receives no more than 20 single doses.

    Intravenously, a patient with chronic kidney disease or weighing less than 50 kg, you can enter no more than 0.5 ml of solution every six hours (for five days no more than 20 single doses).

    The upper limit of the daily dose for parenteral administration of Ketorol for patients younger than 65 years old weighing more than 50 kg is 90 mg, for patients with chronic renal failure and patients weighing less than 50 kg it is 60 mg.

    The drug can be used no more than 5 days in a row.

    To enter the solution in / in for at least 15 seconds. V / m Ketorol is injected deep into the muscle and also slowly.

    The drug begins to act within half an hour after administration. The maximum anesthesia is observed after an hour or two after the injection.

    Gel Ketorol: instructions for use

    Gel (ointment) should be applied to the washed and dried skin. A single dose of the drug is a column 1-2 cm long. Ketorol is spread on the surface of the most painful area with gentle massaging movements of 3-4 p. / Day.

    Re-use of the drug is possible no earlier than 4 hours.

    Apply the gel is allowed no more than 4 times a day. Do not exceed the recommended dose.

    If after 10 days of treatment with Ketorol, the patient's condition does not improve or the pain and inflammation increase, it is necessary to stop using the drug and seek medical help.

    Without consulting a doctor, the gel can be applied for no more than 10 days.

    Drug Interactions for Solution and Ketorol Tablets

    The use of Ketorolaka in combination with other NSAIDs, ASA (acetylsalicylic acid ), ethanol, calcium preparations, Corticotropin and corticosteroids can lead to ulceration of the gastrointestinal mucosa and the development of bleeding from ulcers.

    Joint appointment with Methotrexate helps to increase hepato-and nephrotoxicity, with Paracetamol - nephrotoxicity. WITH Methotrexate ketorolac may be appointed only on condition that Methotrexate It will be used in the lowest possible dose (at the same time plasma concentration indicators should be constantly monitoredmethotrexate ).

    Probenecid reduces volume of distribution and plasma clearance ketorolaka. increases its plasma concentration and increases the period of elimination. Against the background of the application ketorolaka may decrease the clearance of Li and Methotrexate. and also increase the toxicity of these substances.

    Ketorolac. acting as an inhibitor of Pg synthesis in the kidney, reduces the effect diuretics and antihypertensives .

    In case of simultaneous use with narcotic painkillers drugs doses of the latter can be significantly lower.

    Antacid drugs do not change the absorption ketorolaka .

    Increases hypoglycemic effect oral antidiabetic drugs and insulin. which requires dose recalculation.

    Combined use with valproic acid provokes a violation of platelet aggregation.

    When combined with other nephrotoxic drugs (for example, with drugs Au) increases the likelihood of nephrotoxic effects.

    Blocking tubular secretion drugs reduce clearance and increase plasma concentration ketorolaka .

    Drug Interactions for Topical Ketorolac

    It does not exclude the likelihood of pharmacokinetic interaction with competing drugs for binding to plasma proteins.

    The gel should be used with caution in combination with Phenytoin . other NSAIDs diuretics. Digoxin . Cyclosporin. Li drugs, Methotrexate. antidiabetic and antihypertensive drugs .

    Patients using any of the listed drugs should begin treatment with Ketorol only with the approval of the physician.