Nystatin - instructions for use, side effects, reviews, price


Mushrooms of the genus Candida with active reproduction can cause a disease called candidiasis. Also, this disease is called thrush, which is associated with characteristic white discharge. The main cause of the disease is a decrease in immunity, but do not forget about hormonal imbalance, poor diet and other factors. It is also worth mentioning that the disease is not due to the presence of these fungi (in small quantities they can exist in the human body and not cause him harm), namely, a large number of them.

Medicine divides candidiasis into systemic and surface. Systemic candidiasis is not common, although cases of its spread are recorded in absolutely all countries. But superficial - the phenomenon is much more common. It has several forms, among which are allergic rashes, onychia, paronychia, intestinal candidiasis, oral candidiasis and genital candidiasis.

The most common forms of the disease under consideration are the last two: candidiasis of the genital organs and oral candidiasis. The rest in comparison with them appear much less frequently, therefore we will consider them in more detail.

What will the article tell you?

Candidiasis of the genitals

Symptoms of genital candidiasis in both women and men are almost the same and are characterized by the following manifestations:

  • In the genital area begins to burn,
  • White discharge appears,
  • Sexual intercourse is accompanied by pain, as is urination.

It should be noted that more often this disease occurs in women, but the presence of it in men is also not uncommon.

Oral candidiasis

Most often they suffer infants and people over 60 years of age. In the case of the latter, it can be an unpleasant addition to other diseases that cause a decrease in immunity. In adults, such thrush is much less common and its symptoms are as follows:

  • heat,
  • discomfort in the mouth,
  • bleeding and wound formation.

Ignore any form of candidiasis is strongly discouraged. Of course, there is a possibility that it will pass by itself, without treatment, but it will take a lot of time and will be accompanied by very unpleasant symptoms that cause discomfort. In some cases, candidiasis can lead to sepsis. Sepsis is a condition that is caused by the penetration of bacteria into the blood, which in turn can lead to blood infection. Such an outcome does not happen often, but it should be remembered about him. To risk in any case is inexpedient, given that his treatment does not require much time and cost.

What and how to treat candidiasis?

One of the best and proven experience drugs from thrush today is Nystatin. Its principle of action is binding to sterol molecules, after which the protective membrane of the cell of the fungus weakens and dies. It has a particularly devastating effect on fungi of the genus. Candidawhich provoke candidiasis. Perhaps the only drawback of the drug is the fact that it is poorly absorbed into the blood compared to more modern medicines. Otherwise, he is very good and quickly copes with his task.
There are three types of this drug:

Let us consider in more detail each of them. We will study side effects, contraindications, precautions, interaction with other drugs, user reviews on the forum and average prices. Well, instructions for you to understand how to take Nystatin.

Tablets "Nystatin"

  • instructions for use

How to drink Nystatin? Very simple. Tablets are taken inside. Swallow them whole. They need to dissolve only when mucosal candidiasis. There is a daily dose rate of this drug for an adult. It ranges from 1 to 3 million ED. It is necessary to take pills so that to fit into this dose - this is the most important thing. How you will distribute the dose during the day, in general, does not play a special role. The doctor may increase your dose if you have complications, but do not do it yourself without consulting him.

The average duration of treatment is from 10 to 14 days, but with severe stages of the disease, such as generalized and recurrent candidiasis, it becomes necessary to repeat the course of treatment.

  • side effects

No side effects of the drug causes. Nausea, chills and fever are possible, but only when the patient has increased sensitivity to the antibiotic. In such cases, you only need to reduce the dose.

  • contraindications

You can not take the drug for pancreatitis, gastric ulcer, during lactation and, of course, with increased sensitivity to the composition of the drug. In all other respects, there are no restrictions.

  • precautionary measures

For the tablets to work properly, you must complete the full course of treatment. You need to take the drug at regular intervals of time and in any case not to miss the dose. If you missed the dose, you should take it right away. But if the time has come for the next dose, then it is not necessary to take double. Nystatin can increase the sensitivity of the skin to sun exposure, which means it is better to avoid sun treatment.. Tablets "Nystatin" can not be used for the treatment of systemic mycoses!

  • interaction with other drugs

It is not recommended to take Nystatin together with Clotrimazole, since the activity of the latter in this case is significantly reduced.

The overwhelming majority of reviews about tablets are extremely positive. Users quickly get rid of their illness with this drug and recommend it to others.

“How much is such a miracle? Expensive, perhaps? ”- you ask. Relax, the price of goods will not hit anyone's pocket - in very rare cases, it exceeds 100 rubles. Basically, the cost in pharmacies varies from 50 to 90 rubles for 10 pieces.

Candles "Nystatin"

  • instructions for use

To begin with, let's answer the most common question that is often asked in pharmacies and forums: “Where to insert?”. These candles are accepted intravaginally. That is, they are injected deep into the vagina. The dosage regimen is individual for each, but 1-2 suppositories (0.25 million U - 0.5 million U) are prescribed most often 2 times a day for an adult. Before using suppositories, it is necessary to pre-treat the vaginal cavity with furatsilina solution. Candles "Nystatin" are intended exclusively for women. For men from thrush apply pills and ointment.

As in the case of tablets, the duration of treatment lasts an average of 10-14 days.

It is necessary to separately mention the theme of the use of candles during pregnancy. So far, there has been no consensus among doctors about whether they should be prescribed to pregnant women, and their opinions on this issue differ. Even in the instructions for the drug there is a disagreement on this matter. Take candles during pregnancy at your own risk, before necessarily Having consulted with your doctor. But remember that can't use this drug in the early stages of carrying a child, namely in the first three months. The same applies to other drugs against thrush.

  • side effects

Side effects are not observed. Itching and allergic reactions are possible, but, as in the case of tablets, they can occur only with increased sensitivity to the antibiotic.

  • contraindications

In violation of the functions of the liver, duodenal disease, pancreatitis and hypersensitivity to take the drug is strongly discouraged.

  • precautionary measures

During treatment, it is strongly recommended to avoid sex. The simultaneous treatment of your sexual partner is also recommended. It is not necessary to stop taking the drug during menstruation.

  • interaction with other drugs

It is not recommended to take Nystatin together with clotrimazole. The activity of the latter in this case decreases markedly. Also, the drug has a chemical incompatibility with the following substances: salicylic lactic acid, hydrogen peroxide, sodium bicarbonate and potassium permanganate.

Almost all reviews are positive. Isolated cases of negative drug ratings are mainly related to their incorrect use and incorrect distribution of the dosage. But this is not the problem of the candles themselves, but the inattention of the user, or the poor information of his doctor.

Prices for this product are about the same as for tablets - from 30 to 90 rubles for 10 pcs.

Nystatin ointment

  • instructions for use

Ointment "Nystatin"intended for external use only. In no case do not need to use the drug for the treatment of the mouth or nose. Ointment should be applied to the affected surface with a thin layer 1-2 times a day. For a better effect and faster recovery, other nystatin preparations listed above can be applied in parallel. Nystatin cream thrush quite organically combined with them.

The course of treatment is 10-14 days.

  • side effects

Allergic reactions such as itching and rashes may occur. In such cases, it is necessary to carry out symptomatic therapy, and the medicine to cancel.

  • contraindications

Ointment can not be used for pancreatitis, duodenal ulcer and various violations of the liver. And most importantly - in case of hypersensitivity to the substance nystatin.

  • precautionary measures

During the course of treatment, refuse sexual intercourse. If you have fungal diseases of the vagina, then simultaneous treatment of the sexual partner is also recommended. For tubercular and viral skin lesions, it is strongly not recommended to use the drug.

  • interaction with other drugs

Do not use with Clotrimazole due to a decrease in the latter activity with their simultaneous use. A similar effect is also observed with Amphotericin B. In the presence of bivalent ions and fatty acids, the activity of the drug decreases.

The reviews, as in the two previous cases, are mostly positive. People praise the ointment for the fact that it very quickly calms the burning sensation and helps to get rid of thrush. Occasionally there are reviews with an average rating, which users justify by the fact that tablets help them better. But here, in general, everything is individual.

The price of a product is not much different from its counterparts - it also ranges from 40 to 100 rubles.

Does nystatin help with thrush?

It certainly helps! Nystatin is a drug whose effectiveness has been proven over the years. It is able to cure almost any form of thrush in a short period of time. A huge number of positive reviews of people who praise him and thank him for curing his illness, is the best proof of this. And the prices, fortunately, do not bite. But you should also take precautions and consult your doctor. After all, the treatment of thrush often requires an individual approach for everyone and the patient’s attempt to recover on their own without having proper medical qualifications may result in undesirable consequences. Be careful and treat your health with full responsibility, because this is the most expensive thing you have.

Drug Nystatin

Nystatin belongs to a group antifungal drugs and is used for the treatment of candidiasis, which are caused by fungi of the genus Candida and aspergillus. This drug can be used to treat oral candidiasis of the mouth, skin, vagina and intestines, since it is not absorbed into the blood and acts locally on the fungus. Nystatin has no effect on normal bacterial flora. When ingested, it is excreted from the body in an almost unchanged form, along with fecal masses.

Nystatin has a destructive effect on the cell membranes of fungi and, penetrating into the cell, causes its suppression or death. It can be used for a long time, because fungi do not develop resistance to it for a long time. The drug is available in various pharmacological forms and, due to its low toxicity and efficacy, can be used among virtually all groups of patients, excluding pregnant women and individuals with individual intolerance to this drug.

Forms of release

Nystatin is available in various forms:

  • tablets - 250 and 500 thousand units of 10 pieces in a blister, 20 pieces per pack,
  • granules for the preparation of suspensions (Fungostatin) - 100 thousand units per 1 granule, 7.5 g per vial,
  • ointment - 100 thousand units in 1 g, 15 or 30 g in tubes,
  • rectal suppositories - 500 thousand units, 10 pcs. each. packaged,
  • vaginal suppositories - 250 or 500 thousand units, 10 pieces per pack.

Nystatin granules and tablets can be used to treat or prevent fungal infections caused by various causes. Granules are convenient to use for the preparation of suspensions for children. Tablets can be used for the preparation of a solution of Nystatin, and for oral administration.

Rectal and vaginal suppositories include, in addition to Nystatin, a number of additional substances that make it more convenient for the treatment of vaginal candidiasis and lower intestines. Enter suppositories should be after the toilet area of ​​the perineum, following all the recommendations of the doctor.

Nystatin ointment for external use is used to treat skin candida. In addition to Nystatin, it contains components such as white petrolatum and lanolin, which ensure an even distribution of the active substance. If necessary, this ointment can be used not only for the treatment of skin candidiasis, but also for the treatment of vulvar candidiasis and anus zone.

Indications for use

  • Prevention of candidiasis with long-term antibiotic treatment,
  • Prevention of intestinal candidiasis in the preoperative period and after surgery,
  • prevention of candidiasis of the external genital organs with the external use of antibacterial drugs,
  • treatment of candida vagina or organs of the gastrointestinal tract,
  • treatment of candidiasis of the skin or mucous membranes.

Nystatin treatment

How to take Nystatin?
Nystatin tablets can be taken regardless of the meal. It is recommended to swallow them whole (without chopping or chewing). The average duration of the treatment course is about 10 days or 2 weeks.

In some cases, with candidiasis of the oral mucosa, Nystatin tablets can be prescribed as follows: a tablet of 500 thousand units is placed behind the cheek until it is completely resorbed. It is recommended to take after eating and oral hygiene from 3 to 5 times a day.

In the event that the patient suffers from generalized or constantly recurring forms of fungal infection, repeated courses of Nystatin can be repeated with intervals of 2-3 weeks.

Nystatin granules (syn. Fungostatin) can be used for internal and external use in the treatment of candidiasis in children. When preparing a suspension for ingestion, the required amount of granules is diluted in a small amount of cooled boiled water or milk. The resulting suspension is given to drink to the child.

If it is necessary to prepare a suspension for external use, it is necessary to dissolve 2 granules in 200 ml of boiled water. This solution is used for rinsing the mouth or treating the area of ​​the anus or external genital organs.

Suppositories are inserted into the vagina or rectum 2 times a day (after hand hygiene and external genitalia), and the duration of treatment for such forms of candidiasis lasts from 10 to 14 days.

If necessary, the treatment of candidiasis of the skin or mucous membranes apply ointment with Nystatin, which can be administered both independently and in combination with taking the tablet form of the drug. Ointment is applied with a thin layer on areas affected by candidiasis 2 times a day. The duration of treatment is determined by the doctor and, as a rule, is 7-10 days.


  • Tablets for adults - 250 thousand units 6-8 times a day or 500 thousand units 3-4 times a day (if necessary, during the treatment of generalized candidiasis, the dose may be increased by 2 times).
  • Rectal or vaginal suppositories - 250 or 500 thousand units 2 times a day, morning and evening.
  • The ointment is applied with a thin layer 2 times a day on the affected skin with fungi.

Nystatin children

Nystatin is still used in pediatric practice in the treatment of candidiasis in children. Due to the fact that this drug is practically not absorbed into the blood when used externally, it is quite effective and safe for treating children.

Outside use of Nystatin for the treatment of candidiasis of the skin and mucous membranes (thrush) is widely used, since children often suffer from these fungal diseases. For the treatment of skin candidiasis in children can be applied ointment or self-prepared suspension of nystatin from granules or tablets (250 thousand units per 200 ml of boiled water at room temperature).

Some pediatricians recommend using the following composition based on Nystatin to treat oral thrush: powdered tablets (250 thousand units) are mixed with 1 ml of solution from an ampoule with vitamin B12. This solution can lubricate the affected areas of the oral cavity. If necessary, ampoule solution of vitamin B12 can be replaced with water.

The dosage of nystatin for children when administered orally depends on the age of the child:

  • children up to a year - 100 or 125 thousand units 3-4 times a day,
  • from year to 3 years - 250 thousand units 3-4 times a day,
  • from 3 to 13 years old - 250 or 400 thousand units 3-4 times a day,
  • over 13 years old - 250 or 500 thousand units 3-4 times a day.

For convenience of dosing, nystatin granules can be used not as tablets. Dosing in their application is carried out as follows: 100,000 units of Nystatin are contained in one granule, the age dosage is divided into 100 per reception and the amount of granules to be given to the child is obtained.

Nystatin during pregnancy

In recent years, nystatin is rarely assigned to women during pregnancy. This drug, according to the instructions, is contraindicated for use in pregnant women and, due to the presence of a wide range of other antifungal agents, can be successfully replaced by safer antifungal drugs (for example, Pimafucine, Polygynax, Difluzole, etc.).

In rare cases, nystatin tablets or in vaginal suppositories are prescribed for pregnant women, but in these forced cases, their dosage is reduced.

The only safe method of treatment with nystatin during pregnancy can only be considered the use of an ointment based on this drug. When applied topically for the treatment of candidiasis of the mucous membranes or skin, it is not absorbed into the blood and can not harm the unborn child.

Ointment or cream

Nystatin ointment is widely used in the complex treatment of thrush. Doctors recommend starting to apply the ointment (cream) at the first symptoms of fungal disease. Women at the same time need to use candles with nystatin, and men - tablets. To achieve greater efficacy, nystatin ointment must be used in conjunction with tablets or suppositories.

Nystatin ointment for thrush should be applied to the mucosa of the vagina or penis with a thin layer two or three times a day. As a rule, the course of such therapy is no more than two weeks. Further, it is possible to use the ointment for prophylactic purposes once a day. Before applying the ointment should also be carried out hygiene of the external genital organs.

Important! Nystatin ointment for chronic thrush should be used only with preformed medicines or with suppositories. Otherwise the treatment will be ineffective.


Nystatin candles from thrush can be used by women in both chronic and acute forms of fungal pathology. They are effective because they act directly on the affected areas of the vaginal mucosa. Usually suppositories are administered twice per day: in the morning and in the evening. The average course duration is 2 weeks.

The effectiveness of a candle is based on the rapid absorption of the active substance and its rapid effect on the mucous membrane, where the pathogenic fungus is localized and propagated.

Note! The doctor prescribes suppositories for test results. Basically appoint candles for 500 thousand units, but in some cases, the dosage may be 250 thousand units.

Before using candles with nystatin for thrush, a woman needs to do some training. Before you enter the suppository, you must thoroughly wash out (you can make the procedure douching). This must be done in order to clean the walls of the vagina and wash off the discharge. For these hygienic procedures, you can use a decoction of herbs, a weak solution of potassium permanganate or soda, furatsilin.

If the fungal infection spreads in the internal organs (in the intestine or esophagus), then rectal nystatin suppositories are used. Enter them into the rectum twice a day (morning and evening). Before the procedure is better to take a shower or wash well.

Contraindications and side effects

When treating thrush nystatin of any form, you should read the instructions for use and pay attention to the fact that the drug can cause side effects. These include:

  • Digestive disorder, accompanied by nausea, diarrhea, vomiting.
  • The appearance of an allergic reaction in the form of skin rashes, itching, fever.
  • The development of a local allergic reaction (when using candles).

Nystatin vaginal suppositories are one of the most popular remedies for controlling candida infection.

If the treatment of candidiasis Nystatin appear the above phenomena, then the drug should be canceled. Also during the entire course of therapy is not recommended to drink alcohol, because it can reduce the effect of the treatment and cause some side effects, such as nausea or vomiting.

The use of Nystatin in thrush is contraindicated in the following cases:

  • Sensitivity and intolerance by the patient of any component of the drug.
  • Allergy to the components of the drug.
  • Pregnancy and breastfeeding period.
  • Diseases of the digestive system.

Only a doctor, based on the results of tests, can coordinate the course of treatment and give advice on an individual basis, how to take Nystatin for candidiasis

Important recommendations for the treatment of candidiasis

During the treatment of thrush Nystatin, you must adhere to the following basic rules:

  • Women are not recommended to use vaginal suppositories in the period of menstruation.
  • Do not drink alcohol at the same time.
  • To limit the use of fried, smoked and salted.
  • It is not recommended to take Clotrimazole at the same time, as the effect of treatment will decrease.
  • The course of treatment must pass both partners.
  • For the period of therapy it is better to abstain from sexual relations.
  • Conduct a repeated therapeutic course in 14-20 days.

Treatment of candidiasis in the early stages of a woman can be carried out using candles and ointment with nystatin

Treatment of thrush Nystatin in women and men allows in a relatively short time to achieve the desired effect. The drug affects fungal infections at any stage of the disease. But it should be remembered that you should not choose medicines yourself for treatment, as this may lead to undesirable health consequences.

Symptoms and treatment of chronic stage of thrush

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Vaginal lesions of the vagina are called yeast-like fungi Candida. The disease occurs predominantly in women of reproductive age. Candida are part of the permanent microflora of the vulvar mucosa. When creating favorable conditions, protozoa begin to actively grow and multiply, causing irritation and inflammation of the reproductive organs.

Causes of chronic thrush

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Vaginal candidiasis is most often diagnosed with a weakened immune system. Provocative factors can serve:

  • concomitant diseases of internal organs,
  • endocrine disorders: diabetes, hyperthyroidism,
  • hypothermia
  • poor hygiene,
  • antibiotic treatment
  • promiscuity,
  • chronic dysbiosis,
  • wearing tight clothing, underwear made of synthetic fabrics,
  • taking oral contraceptives.

Infection with thrush occurs during sexual intercourse, through personal hygiene items. Chronic candidiasis develops if the acute stage was not treated on time. Gradually, the symptoms subside, appear weaker, but periodically relapses occur. A cold, a viral disease, hypothermia, a stressful situation, and hormonal disorders can provoke an exacerbation. Most often, the recurrent form of thrush appears before menstruation.

Main symptoms of chronic thrush

In the acute stage, women are worried about severe itching, burning and rash on the vulva, white discharge with an unpleasant sour smell, similar to cottage cheese. Discomfort occurs during urination, painful intercourse. Due to constant scratching, microcracks appear on the outer mucous membranes, the tissues turn red and swell.

The acute period can last up to 2 months, then chronic candidiasis develops. Fungi deeply affect the mucous membranes, forming sites of infiltration, erosion. Symptoms of recurrent form of the disease in remission are less pronounced, there is a cheesy discharge, slight burning and itching of the genital organs, aggravated in the evening and at night.

Chronic thrush in women is manifested by periodic exacerbations. Again, there are typical signs of candidal colpitis, urinary system is involved in the inflammatory process. Cystitis, pyelonephritis can develop, sometimes on the skin in the perineum, inguinal folds, painful ulcers, covered with a whitish bloom.

If you do not treat chronic thrush for a long time, the disease can lead to serious complications. Women form adhesions of the fallopian tubes, increasing the risk of infection of the bladder and kidneys. The adhesions process leads to obstruction of the pipes, as a result, PMS symptoms increase, the menstrual cycle is disturbed, and infertility develops.

Diagnosis and treatment of recurrent candidiasis

The diagnosis of recurrent thrush is confirmed after an examination, a patient survey, and test results on the composition of the vaginal microflora. Laboratory studies allow to exclude other sexually transmitted infections or to identify a mixed type of pathology, to choose a medicine to which pathogenic microorganisms are most sensitive.

How to cure chronic thrush, what drugs help to get rid of itching and discharge? The scheme of treatment is chosen by the gynecologist, taking into account the severity of the disease and the presence of complications. Recurrent thrush is treated with the same drugs as the acute form, but it will take much longer to completely get rid of the disease. The doctor prescribes topical application of vaginal suppositories and taking antifungal tablets inside.

Preparations for the treatment of chronic thrush in women:

  • Fluconazole is an oral capsule. Shown for the treatment of generalized forms of candidiasis of the genital organs, intestines, urinary tract. Fluconazole is used for the treatment and prevention of relapses. Capsules are taken once a month, the course of treatment is from 6 to 12 months. In case of complicated forms, a large dosage of antimycotics is prescribed.

  • Clotrimazole vaginal tablets are an antibacterial, antifungal broad-spectrum drug. Candles are used if tortured thrush, manifested by frequent relapses. Effective drug and mixed types of infection. For the treatment of chronic candidiasis, suppositories are prescribed and external treatment of the genital organs with Clotrimazole cream for 10-14 days.

  • Nystatin destroys parasitic and yeast fungi. The drug is used for the treatment of the acute form and prevention of recurrence of thrush. Take pills inside, topically inject vaginal suppositories for 10–14 days. Treatment of chronic candidiasis is carried out courses with a break for 2-3 weeks.

  • Candles Livarol have a fungicidal effect in the period of exacerbation of thrush or to prevent relapse. Suppositories are inserted into the vagina 1 time per day for 10 days.

  • Candide Gel is used for intravaginal administration for the treatment of vaginal mucous membranes. Procedures are repeated for 6 days.

How to treat chronic thrush in women - determines the gynecologist. Self-administration of pills and the use of suppositories can aggravate the course of the disease, cause side effects and the development of complications. Before starting therapy, tests and examination by a doctor are required. With a mixed type of infection, antifungal drugs will not give the desired result.

Treatment must be carried out by both sexual partners, otherwise re-infection occurs. It is necessary to take pills strictly according to the prescribed scheme, even if the symptoms of chronic thrush have already passed. An interrupted course threatens to re-develop a fungal infection.

If during the period of treatment the menstruation does not start using tampons, they increase the symptoms of candidiasis. It is necessary to give preference to laying with the top layer from organic cotton.

Rehabilitation Therapy

After eliminating the fungal infection, it is necessary to normalize the vaginal microflora, colonizing the mucous membranes with beneficial bacteria. This reduces the risk of reproduction of yeast microorganisms, increases local immunity.

Apply candles and gels with bifidobacteria to restore microflora:

  • Bifidumbacterin.

But it is possible to use the means only with the permission of the doctor; a relapse can occur with an undertreated thrush.

In addition to medical treatment, physiotherapeutic procedures are prescribed. Magnetic tolerance, electrophoresis with zinc, dirt, laser technologies help to strengthen local immunity, increase resistance to pathogenic microorganisms.

Extended Examination

Diabetes mellitus, diseases of the thyroid gland can cause the development of thrush. These pathologies develop due to a violation of the hormonal regulation of the body and require special treatment from an endocrinologist. Thrush often appears on the background of these ailments, since the immune system is weakened and a favorable environment for the growth of fungi is created.

The use of local antimycotics in such cases will not give results, the elimination of the main cause of the disease is required. With diabetes, you need to control blood sugar levels. Thyroid diseases are treated by correcting the hormone balance of thyroid hormones.

To provoke the development of thrush can nevrovrely cured tooth, inflamed gums, intestinal dysbiosis or sinusitis. It should eliminate the foci of infection, consult with specialized experts.

The required drugs are selected by the attending physician, taking into account the individual characteristics, age of the patient and the severity of the disease. Be sure to receive vitamins and immunomodulators: Immudon, Echinacea.

Prevention of chronic candidiasis

In order not to be bothered by thrush every month, you must comply with measures to prevent exacerbations:

  • not to allow hypothermia,
  • treat concomitant diseases in time,
  • wear cotton underwear,
  • avoid casual sex
  • limit the use of sweets, flour products, alcoholic beverages,
  • wash 2 times a day, you can not use intimate gels with antibacterial effect,
  • when using daily pads, you need to replace them 2-3 times a day,
  • antibiotics should be taken only on prescription.

In severe forms of chronic thrush during remission, antimycotics are prescribed in the form of tablets or vaginal suppositories.

Treatment of recurrent forms of vaginal candidiasis is carried out comprehensively. You must use antifungal drugs for local treatment of the genital organs and internal administration. It is important to strengthen the immune system, restore the vaginal microflora using bifidobacteria.

Nystatin is a polyene antibiotic

Nystatin is a drug that is widely used to treat fungal infections that are caused by yeast or yeast-like fungi.

The drug can be used in all groups of patients (men, women (with restrictions during pregnancy, lactation) and children), however, currently its use is limited (gynecology, obstetrics, prevention of candidiasis in surgery after extensive surgery or long-term antibiotic therapy in the treatment of internal diseases).

The main active ingredient in nystatin is a polyene antibiotic, the main mechanism of action of which is the binding to specific molecules (complex sterol molecules) in the membranes. As a result of this interaction, the protective function of the cell membrane is disrupted, an uncontrolled flow of ions into the cell occurs, which ultimately leads to its death.

In low concentrations it slows down and in high concentrations it kills the cell of the fungus.

The main spectrum of action: yeast-like fungi (especially in relation to Candida alb.), Aspergillus microorganisms.

Release form

The tool is available in 3 forms:

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  • Tablets - provide a comprehensive treatment when the infection in the intestine or is localized in several places
  • Candles - with vaginal candidiasis,
  • The ointment is suitable for the treatment of skin and nails.

Instructions for use Nystatin

The treatment is not tied to food intake, the course lasts at least 10 days. Take twice a day with ½ glass of water.

Children for internal use appoint a means in the form of granules. Of them prepare the suspension, diluting with water.The granules are dissolved in water to obtain a rinse.

Vaginal injected after hygiene procedures in the morning and at night in the supine position.

Anal use after cleansing the intestines, also twice a day.

Ointment smear external affected areas twice a day, often combine the ointment with tablets.

special instructions

  • Eliminate alcohol: it affects carbohydrate metabolism, stimulates the reproduction of Candida fungi,
  • Appointment with Clotrimazole leads to a decrease in the concentration of the latter in the blood and a decrease in its therapeutic effect.
  • Follow a diet - limit sweets and dairy products, increase the amount of fiber,
  • For reddening of the skin, rash, stop treatment,
  • Do not use the drug in the form of candles during menstruation,
  • It is recommended for the duration of treatment to refrain from intimate life.

Method of use of nystatin for thrush

The treatment regimen for acute thrush nystatin in women is as follows: vaginal suppositories are administered one candle (0.5 million IU) 2 times a day for at least 10 days (up to 14 days). In men, tablets of 0.25 million ED are used - 0.5 million ED 4 times a day for 14 days. Locally applied ointment - applied to the affected lesions 2 times a day for 10 days.

In chronic thrush, the use of Nystatin tablet form with topical ointment (in men) or suppositories (in women) is mandatory. The timing and treatment regimen, the dose of drugs, combination with other antifungal drugs are determined by the doctor.

Reviews of the drug Nystatin

According to reviews of patients who have been treated with Nystatin, the drug has established itself as a quick relief from symptoms - the effect appears on the 2-3 day of treatment, the symptoms disappear after 7 days of therapy. Side effects are rare, easily tolerated.

Among those noted by patients is a slight decrease in appetite, a feeling of heaviness in the stomach, especially when taken on an empty stomach. Very rarely, nausea and other disorders of the gastrointestinal tract occur. To avoid them, you should take the medicine an hour after eating.

Oral administration of the tablet preparation is more difficult, and ointments and suppositories almost do not cause side effects.

Why is Terzhinan prescribed for thrush?

Terzhinan is a vaginal tablets that have antifungal, anti-trichomonas, anti-inflammatory and anti-bacterial action. Suitable for complex treatment of infectious gynecological diseases, at least - for prevention. Effective against sexually transmitted diseases, it is prescribed for candidiasis, trichomoniasis, chlamydia, etc. Suitable for pregnant and lactating women.

The composition of the drug Terzhinan

The high efficacy of the drug is due to the effect on the fungus of four active ingredients, the combination of which provides a quick recovery:

  • Nystatin is an antibiotic acting against a fungal infection
  • Ternidazole - antifungal agent,
  • neomycin - have a inhibitory effect on pathogens, regardless of their origin,
  • Prednisone - a hormone that has anti-inflammatory and antipruritic effect, eases the symptoms of the disease.

Who are contraindicated candles

Terzhinan is well tolerated by the body, it is suitable for use during pregnancy and lactation. Individual intolerance to the components that make up the drug becomes a contraindication. No pills are prescribed for young girls under the age of 16 due to the lack of information on the safety of components on the children's body.

How to take pills

Take Terzhinan with thrush need for the scheme: every day for 1 tablet. How many days the treatment lasts is decided by the doctor, but for women with chronic candidiasis, candles will need to be administered within 10 days.

The tablets are dry, so before use they need to be slightly moistened with warm water, and then inserted deep into the vagina and take a horizontal position. The procedure is carried out at bedtime in order to avoid a candle falling out or its leakage in an already dissolved state.

Side effects in women after the use of the drug are rarely observed, perhaps a feeling of burning and irritation of the intimate area.

If the state does not improve for a long time, then treatment with a doctor is required. In women, there is a decrease in itching and burning after one (maximum, three) accepted Terzhinan candle. And if the pills do not bring results, you will need to undergo a re-examination or to combine the drug with other drugs for the treatment of candidiasis.

Terzhinan for pregnant women

In pregnant women and gynecologists, Terzhinan does not cause concern, since its safety for the fetus has been proven by many years of experience in medicine. In the waiting period of the baby candles are preferential over competitors:

  • even with prolonged use, the substances do not accumulate in the body and are practically not absorbed in the blood, so the drug has no effect on the child,
  • high efficiency makes it possible to quickly get rid of the unpleasant symptoms of thrush within a couple of days after the start of treatment, which during pregnancy is important not less than proper treatment,
  • Candles have a wide spectrum of action and are effective against many pathogenic microorganisms, which makes it possible to use only one drug for the treatment of several diseases.

Terzhinan appointed from the second trimester of pregnancy, but studies conducted in Europe showed that the drug has no effect on the fetus and in the early stages. But precaution in our country comes first, so pills are not prescribed before 12 weeks and are not allowed to use for a long time. How much is the course - decides the gynecologist. In pregnant women, the treatment regimen is adjusted individually, after the examination.

The drug is not contraindicated during lactation. A young mother may not stop breastfeeding during treatment.

Nystatin for men with candidiasis

In the treatment of candidiasis in men, in most cases, Nystatin ointment is applied, which is applied to the head of the penis, as well as other affected areas several times a day, for a week or 10 days. Apply a small amount of ointment, while it should be gently rubbed into the skin. It is necessary to apply at least 2 times a day.

The combined method of therapy is also quite often used when local treatment is combined with the use of tablets.. In the case of the addition of therapeutic therapy with pills, it is necessary to take Nystatin for thrush from 2 to 4 times a day, in the dosage specified by the doctor. This approach greatly increases the effectiveness of treatment.

It is important to follow a few rules, in particular:

  • It is forbidden to use any alcoholic beverages during the treatment period.
  • During the period of treatment should exclude the consumption of spicy, very fatty, as well as salty foods.
  • It is necessary to stop sex until complete recovery.
  • Personal hygiene rules should be more carefully observed, washing the genitals with special means or decoction of herbs several times a day, soaking them with soft paper towels or napkins after the procedure.
  • It is important to abandon tight fitting pants from synthetics. It should be (at least for the period of treatment with ointment) to give preference to natural cotton spacious pants.

The effectiveness of the drug for thrush

The drug is very effective effect on pathogenic yeast-like fungi, primarily on those that belong to the genus Candida and cause thrush of various species.

The tool has a strictly selective effect, destroying only fungi, so other microorganisms that are useful and make up the normal flora are not destroyed. In this way, Nystatin does not cause dysbiosis and other complications, which distinguishes it from other antibiotics of this group..

Nystatin can be treated for thrush of various species, including not only on the genitals, but also on the skin surface, mucous membranes and even in the internal organs: in the lungs, in the gastrointestinal system or in the kidneys, Nystatin is also used for candidiasis of the mouth, larynx and tonsils.

In some cases, nystatin is also prescribed as prevention of candidiasis, for example, with a strong weakening of the immune system, depletion of the body or long-term treatment with antibiotics, especially those belonging to the penicillin group.

A diverse form of release of Nystatin allows you to treat thrush in people of any age and gender, regardless of where candidiasis is located.

Side effects and contraindications

Of course, with all its safety and selectivity of action, the tool has some contraindications, in particular Nystatin can not be used:

  • For the treatment of thrush in the period of carrying a baby, as well as when breastfeeding a baby.
  • If you are allergic to any of the components of the product, especially to the main substance.
  • In the presence of diseases of the digestive system, for example, ulcerative lesions of the intestine or stomach, cholecystitis, hepatitis, pancreatitis.

If you violate the indicated dosage or dosage regimen, do not follow the medical instructions and restrictions, or prescribe a remedy yourself, negative reactions may occur in the form of:

  • Chilliness or a sharp rise in temperature.
  • The occurrence of nausea, diarrhea, bouts of vomiting.
  • Decreased appetite.
  • Dehydration caused by diarrhea and other gastrointestinal disorders.
  • The appearance of allergic reactions, mainly skin.

Analogs of the drug

Modern pharmacology offers an incredibly extensive list of various preparations for thrush in various forms. Pharmacies offer a variety of options for the combined treatment of similar drugs, since in virtually every name there are not only tablets or capsules for internal use, but also ointments, creams, gels, vaginal suppositories, and also powders for the preparation of suspensions, syrups and solutions.

Of course, not every tool is represented by such a wide variety of dosage forms, but almost everything, like Nystatin, can be used in the form of tablets, ointments and suppositories.

Analogs of Nystatin can be called some drugs of a number of polyene antibiotics, for example: Natamycin and Left.

It is also possible to attribute to the analogues several agents of the imidazole series, in particular: Miconazole, Ketoconazole, Clotrimazole.

Treat nystatin analogs and some triazoles, for example: Itraconazole and Fluconazole.

Additional Information

A good and effective tool that can be purchased for a small price. This site is given a very detailed instruction that allows you to understand the composition of the drug, but also in the method of its use. It is worth remembering that some components of nystatin can cause allergic reactions. This tool can not be used during pregnancy and lactation.

I tried these candles from thrush. And I want to say that they coped with their task. Everything has passed, I am very happy about it. And the most important thing is that the surprisingly low price of this drug. The course I took 10 days. That is, I needed two packs) And yet, all the same, do not use it without consulting a doctor. For example, the doctor wrote me out, I myself would not buy anything.

How best to apply at the initial stage? Separately candles, or candles with pills?

What dose of nystatin is used to prevent thrush in the case of antibiotics?

The use of Nystatin for the treatment of vaginal candidiasis (thrush)

According to medical statistics, eight out of ten women of childbearing age regularly encounter the problem of excessively active reproduction of the fungus Candida, which provokes unpleasant sensations in the genital area and abundant secretions of a granular consistency with a sharp yeast odor. In the absence of proper treatment, thrush (vaginal candidiasis) can not only go from the acute to the chronic stage, but also provoke the development of complications, therefore, if symptoms of the disease are found, it is worthwhile to immediately consult a doctor. The article details the main indications and contraindications for the use of the drug Nystatin for thrush (candidiasis), describes in detail the instructions for using Nystatin for thrush, possible side effects, the principle of Nystatin, the release form (Nystatin tablets, vaginal and rectal nystatin suppositories).

The principle of action of Nystatin

One of the most effective means of eliminating pathogens of thrush is Nystatin, produced in the form of rectal and vaginal suppositories, as well as ointments and tablets. The principle of action of the drug Nystatin is to suppress the process of reproduction of the fungus, followed by the destruction of pathogens by creating around them an impermeable nutrient and liquid film. With frequent use of the drug Nystatin in bacteria can develop immunity to it, however, subject to the regimen prescribed by the doctor, the drug has an almost instant effect. Also, for the treatment of candidiasis, doctors often use such a drug as Miramistin, for more information on the use of such an agent for the treatment of vaginal candidiasis can be found in the article: Miramistin for thrush (candidiasis), detailed instructions for using Miramistin.

Vaginal suppositories Nystatin, application

Nystatin vaginal suppositories are prescribed based on the results of seeding vaginal discharge, which determines the degree of sensitivity of pathogenic bacteria to the active substances of the drug. Often, the doctor prescribes a one-time use of vaginal suppositories and ointments, while the scheme of use of drugs is as follows:

1 Cleansing of the genital organs by washing with warm water and intimate hygiene gel or baby soap.

2 The introduction of candles into the vagina.

3 Treatment of the inner side of the thighs and the crotch area with ointment.

The standard course of treatment with vaginal suppositories and ointment Nystatin is 2 weeks.

Rectal candles Nystatin, application

If, against the background of thrush, the patient develops rectal candidiasis, in most cases the doctor prescribes rectal nystatin suppositories, which quickly and effectively eliminate both the disease causing bacteria and the consequences of their life activity.

Contraindications to the use of rectal suppositories are:

2 lactation period

3 individual intolerance to the components of the drug.

In the absence of contraindications, to enhance the therapeutic effect of the doctor may prescribe an additional dose of Nystatin tablets. The standard course of treatment is 2 weeks, the dosage of the tablets is determined by the gynecologist, depending on the results of the patient's tests.

Nystatin tablets when used

Nystatin tablets come in a carton with a blister containing 10 units of the drug, or in a glass or plastic jar containing 20 units of the drug. Tablets covered with a yellow film can be taken orally, as well as making a solution for intravaginal use. In some cases, the doctor may prescribe another drug for the treatment of thrush, such as Fluconazole, for more information on the use of such a remedy for the treatment of candidiasis can be found in the article: instructions for use of Fluconazole for the treatment of thrush.

Standard treatment regimen for nystatin with thrush (candidiasis)

Not everyone knows how to properly use the drug Nystatin for thrush. The use of any drug for the treatment of thrush (candidiasis), provides for the knowledge of what form of development of candidiasis. At the acute stage of development of thrush, the doctor prescribes vaginal suppositories Nystatin together with ointment. Subject to the recommendations of a specialist, recovery occurs on the 10th day of the use of medicines. A thrush that has passed into the chronic stage is difficult to cure. As a rule, to completely suppress the process of reproduction of harmful bacteria, it is necessary to undergo several courses of treatment with Nystatin with an interval of 2-3 weeks. In the intervals between treatments, a specialist takes tests to monitor the situation. An article about how to get rid of thrush once and for all, how to cure a thrush (candidiasis) can be useful.

What should not be done during treatment with Nystatin?

During treatment with Nystatin, it is recommended to refrain from:

1 drinking alcohol,

2 use of the drug rectally and vaginally during menstruation (vaginal discharge prevents the absorption of the active components of the drug),

3 sex contacts

4 administrations of antacids containing magnesium, aluminum and calcium (Maalox, Almagel, etc.),

5 of the use of Clotrimazole (the substances that make up Nystatin reduce the effectiveness of the active ingredients of the antifungal cream).

With the observance of the above rules, relief of the symptoms of thrush occurs already in 3-5 days of treatment. In order to reduce the risk of reinfection, it is recommended to undergo a course of treatment with Nystatin together with a partner. Существует целый ряд других препаратов для лечения кандидоза, если какой-то конкретный препарат не подходит ввиду определенных особенностей. Так во многих случаях врач может назначить мазь Клотримазол для лечения молочницы, которая является одним из эффективных средств для лечения симптомов проявления грибка кандида.

Противопоказания к применению Нистатина при кандидозе

Препарат запрещено принимать:

1 в период лактации,

2 during pregnancy

3 with intolerance included in the composition of the drug substances,

4 in the presence of gastrointestinal diseases,

5 with liver dysfunction.

If there are one or more contraindications to taking the drug, the doctor replaces Nystatin with another drug.

Side effects of taking Nystatin

In rare cases, the use of Nystatin can provoke:

2 abdominal pains,

5 decreased appetite

7 sharp increase in body temperature.

When anxiety symptoms appear, stop taking the drug and consult your doctor.

The use of Nystatin for the treatment of candidiasis (thrush) in children

Nystatin has established itself as a highly effective treatment for pediatric candidiasis of the larynx. Pediatricians advise to dissolve a drug tablet pounded into powder at a dosage of 250000 IU in a 1 ml ampoule of vitamin B12 and lubricate the areas of the oral cavity affected by fungus with the mixture obtained. As an alternative to vitamin B12, you can use regular boiled water.

The scheme of use of the drug is determined depending on the age of the child:

10-12 months: 100-125000 IU,

1-3 years: 250,000 IU,

3-13 years old: 250-400000 IU,

over 13 years old: 250-500000 U.

If the dosage prescribed by a doctor is complied with, relief of the symptoms of candidiasis occurs after 2-3 days of using the medicinal solution.

The history of the drug Nystatin

Nystatin is an antifungal antibiotic of the first generation, synthesized on the basis of the colonies of the microorganism Streptomyces noursei. Morphologically, it refers to a kind of actinomycetes, a peculiar form of life, having signs of bacteria and fungi. The most famous antibiotics that gave these creatures to humanity became Streptomycin, which saved millions of lives in various wars in the middle of the 20th century. In the late 40s, research revealed antifungal activity of substances secreted by actinomycetes. Thus, a number of polyene antifungal drugs used in the treatment of a variety of mycoses, including thrush, have arisen to this day. Antibiotics are used almost unchanged, since fungi have virtually no resistance to them. The only thing that scientists did was develop a special lipophilic form of polyene drugs. In it, the molecule of the antibiotic is connected by a special component, which is separated from it only when it encounters a cell of the target fungus. This can significantly reduce the toxicity of drugs, which, unfortunately, remains the main drawback of all antifungal and antimicrobial agents.

How does nystatin?

The biochemical mechanism of action of Nystatin and all other polyene antimycotics is based on the presence of double carbon-hydrogen bonds in the drug molecule, which cause Nystatin's tropism to the structures of the membrane of fungi. As a result, the Nystatin molecule manages to integrate into the membrane, through which water and the ions dissolved in it immediately flow into the pathogen's cell uncontrollably. Even if the fungus has enough strength to seal the hole, its development slows down. But in most cases, polyenes exhibit fungicidal activity — an ill-fated fungal cell is simply torn apart, its lysis occurs.

Nystatin has a very selective activity, it is embedded only in sterols and has almost no effect on bacteria and viruses. In high concentrations, it can cause damage to the simplest (trichomonads) and amoebas. At the same time, there are some fungi that Nystatin has little effect on, such as dermatomycetes, which cause skin diseases. In total, about 400 species of pathogenic or opportunistic fungi are known today, so the fact that Nystatin does not cope with them equally well is not surprising.

Nystatin is still one of the most effective remedies for thrush. Later antimycotics of the polyene series are successfully used to treat systemic fungal diseases, including those affecting the brain and spinal cord.

Nystatin: dosage forms

In case of candidiasis, nystatin is used in the form of vaginal and rectal suppositories, ointments and creams, as well as tablets and suspensions for oral administration. It is important to remember: Nystatin, like all polyenes, is practically not absorbed in the gastrointestinal tract. Their oral administration is justified only in the case of dysbacteriosis and identified candidiasis of the large intestine, as well as in the prevention of candidiasis before and after surgical interventions, suppressive therapy, treatment with antibiotics. In all other cases, the application is only local. If a gynecologist prescribes nystatin in the form of tablets for thrush to a girl or woman, then most likely she misunderstood something, and the doctor meant nystatin candles. Drinking Nystatin tablets for vaginal candidiasis is as useless as swallowing vaginal suppositories.

By the way, strong agents of the polyene series, for example, Amphotericin B is administered intravenously. They are able to treat severe visceral mycoses, from which half a century ago there were no medical devices.

It should be noted that Nystatin in Russia is classified as a vital and essential drug (VED) as a means of treatment and prevention of candidiasis of the gastrointestinal tract.

Nystatin for vaginal thrush

Of course, in most cases, the drug is used by girls and women suffering from vaginal thrush. If a woman has a regular sexual partner, then local prevention is indicated for him. In any case, a man can pass scraping from the mucous membrane of the penis, which will show the presence of an increased number of fungi Candida with pseudomycelium - it is the latter that shows that the mushrooms have taken the path of war.

Nystatin candles for thrush for vaginal and rectal use are very similar to each other and are interchangeable. Vaginal suppositories - 2.5 g, and a little less than rectal rectal - 2.1 g. Suppositories should be inserted in the prone position as deep as possible twice a day (in the morning and evening). At the time of treatment you need to stop all sexual contact. During the monthly treatment is not interrupted. The duration of the course is prescribed by the doctor, but usually it lasts 10 to 14 days. If the unpleasant symptoms disappear, you should not interrupt therapy anyway, since withdrawal of the drug will almost certainly lead to chronic infection and relapse after 1 to 2 months.

Candles are sold in blisters of 4 or 6 pieces. In a cardboard bundle, usually 2 blisters with candles.

Side effects with vaginal application are possible only with individual intolerance to the drug. The absorption of the drug through the vaginal mucosa or rectum is even worse than through the intestinal mucosa, so the drug in the form of suppositories is effective for local use. However, doctors do not recommend treating thrush during pregnancy and lactation with medical drugs. No direct teratogenic effect on the fetus has been identified, but doctors prefer not to risk it.

Nystatin with dysbiosis and intestinal candidiasis

If dysbacteriosis has developed as a result of therapy with antibiotics or corticosteroids and thrush is present against its background, Nystatin is used in the form of rectal suppositories and tablets. Candles put in the same way as vaginal suppositories. Before the procedure, you need to make a cleansing enema.

Nystatin tablets from thrush drink 500 thousand units 3 - 4 times a day. In severe intestinal candidiasis, the maximum dose of 6 million units per day (12 tablets) is strictly under the supervision of a physician. Despite the poor absorption of the drug in the blood, the loading dose can cause toxic damage to the liver and adverse effects on the gastrointestinal tract.

Recently, doctors are increasingly refusing treatment by Nystatin intestinal candidiasis in favor of the use of systemic drugs acting on Candida fungi through the blood.

The instructions for use do not recommend the use of Nystatin tablets for people with a stomach ulcer and duodenal ulcer, with pancreatitis, with diseases of the liver and gall bladder.

Some unscrupulous authors write about the possibility of using Nystatin tablets in the treatment of systemic mycoses, including those caused by the Candida fungus. This information is not true and remains on the conscience of the authors.

Ointments for external use

The safest in terms of possible side effects. Designed for the treatment of candidiasis of the skin, external genital organs and candidal vaginitis by swabs inside. Nystatin ointment is applied with a thin layer on the affected surface 1 - 2 times a day. Before applying, the skin, hand, foot should be washed with warm water and soap or antiseptic.

Interaction with other drugs

Nystatin for thrush is usually prescribed in monotherapy mode. There is evidence that when used in conjunction with antifungal drugs from the group of azoles (clotrimazole, ketoconazole), the effect of the latter is weakened. Like any antibiotic, nystatin when taken orally can not be combined with alcohol. The latter enhances the absorption of the drug, which can adversely affect the liver. In general, a tangible effect on the action of other drugs in oral administration should not be expected due to poor absorbability in the intestine, and when applied topically, there is little interaction.

Price Nystatin

The price of drugs Nystatin low, is available to all categories of persons. The cost of tablets 100 pieces of 500 thousand units. from 130 rubles.

Candles vaginal 10 pieces of 500 thousand units. from 63 rubles.

Rectal candles 10 pieces of 500 thousand units. from 82 rubles.

Ointment 100 thousand units. 15g from 39 rubles, 30g from 67 rubles.

Nystatin reviews

July 11, 2014 at 2:43 pm

Nystatin is a polyene antifungal antibiotic. It is highly active against yeast-like fungi of the genus Candida. Previously, when using the antibiotic, patients immediately prescribed this drug. This was done so that the pathogenic fungal microflora does not appear in the body under the action of the antibiotic. The form of release of this drug is in the form of powder, tablets, candles and ointment. The cost of tablets (20 pieces) -15.70 rubles - a penny. True, I heard that finding it in pharmacies is not so easy. But in the nearest pharmacy a week ago, I calmly bought it. And with regards to taste, it is simply impossible muck. Against the background of complex treatment, the drug gives positive results (as confirmed by tests). Replace this drug with fluconazole. The cost of which is many times more than nystatin.

June 20, 2016 at 8:34 pm

In the fight against thrush - all means are good, but not all have the same power of interaction on the nasty yeast-like fungus of the genus Candida. Nystatin was one of the first drugs in my fairly extensive practice to destroy the fungus. Quite a convenient form of release (candles), reasonable price, but still more minuses. First of all - the duration of treatment (up to 10 days), secondly - candles have the unpleasant property of soiling clothes, and in general they can be used only before bedtime to consolidate the effect of treatment. Well, and the most important - how many times I used them, the thrush all the same came back. Therefore, Nystatin for me in the black list of drugs for the extermination of yeast-like fungus.

December 23, 2016 at 21:27

I drink it in conjunction with antibiotics, as the use of antibiotics provokes thrush (I apologize for being blunt). But it is very convenient and good, and most importantly not an expensive drug. Previously, he was in the form of children, but recently I learned that he was no longer released for children, since no clinical studies were conducted on children. So many years they have been treating children, and here they haven’t done any research on you ... Well, at least an adult wasn’t canceled and the price wasn’t raised. I bought it for 125 rubles, in a package of 100 tablets. Beauty, given the fact that lately I often forgive, it will be useful to me. And if, against the background of inflammation, the first signs of thrush appear, I immediately begin to take Nystatin.

It seems that the author of the last review does not fully understand when and how to take Nystatin ...

About the drug

The basis of the drug - antibiotic polyene group. Its peculiarity is that it inhibits the cells of the fungus Candida, which is the cause of the development of the symptoms of thrush in women. At the same time the agent does not affect the beneficial bacteria. Thus, Nystatin has a selective effect.

Drug release forms:

  • pills in a yellow shell,
  • vaginal suppositories
  • ointment in tubes.

Vaginal suppositories with Nystatin are used for vaginal candidiasis. Their introduction is recommended after hygiene procedures.

The ointment is intended for therapy for candidiasis of the skin, but it can also be used for thrush in the vagina, as well as in the anus.

During pregnancy

Pregnancy is a contraindication for taking this drug. However, the instructions indicate that the use is possible if the benefit to the mother is more important than the risk to the baby. In this case, admission is permissible only under the supervision of a physician.

In addition, currently there are other drugs that can be used to treat thrush during pregnancy, and which do not have a negative impact.

Recommendations and price

When taking the drug should follow the following recommendations:

  • combination of medication with alcohol is unacceptable,
  • with the passage of therapy, it is necessary to postpone intimate relationships until recovery,
  • candles do not apply during menstruation,
  • treatment of the sexual partner is necessary.

The cost of the drug depends on the form of release and the manufacturer, as well as the policy of the pharmacy. Average prices for Nystatin:

  • tablets, pack of 20 pcs. - from 15 rubles,
  • vaginal suppositories, pack of 10 pcs. - from 35 rubles,
  • ointment, tuba - from 20 rubles.

Nystatin is an effective remedy for candidiasis in women. However, its use should be prescribed by a doctor in order to avoid unpleasant consequences.

Nystatin as a known remedy for thrush

Candida fungi, which actually cause the disease, are present in the body of almost every healthy person. The problem occurs when they begin to multiply excessively intensively due to concomitant adverse factors. Such factors can be a weakening of the immune system, colds, pregnancy, antibiotics, severe stress, contact with an infected sexual partner. Thus, no one is immune from the occurrence of the disease. Candidiasis can manifest in different parts of the body - on the genitals, in the mouth, on the skin, in the intestines.

Nystatin is an effective and widely known treatment of thrush, which has been successfully used for many years to combat the disease. Nystatin has various forms of release (tablets, ointment, vaginal and rectal suppositories), which ensures its effective use for the treatment of different patients.

Basic properties and release forms

The drug Nystatin is an antibiotic, the destructive effect of which is directed to the fungi of the genus Candida and aspergillus. The main active ingredient of the drug is nystatin. In small quantities it slows the cells of the fungus, in large quantities it kills. Poorly absorbed in the gastrointestinal tract, which explains its gentle effect on the body.

Among the advantages of the drug - efficacy, low toxicity and low cost.

But some doctors consider Nystatin to be an outdated remedy with many side effects, and therefore more modern drug analogues are prescribed. In addition, some strains of Candida fungi are capable of producing resistance to nystatin.

The drug is available in these basic forms:

  • pills - small, round shape, light yellow color, dosage 250, 500 thousand. Units, excipients - sugar, calcium stearate, talc, potato starch, dyes,
  • ointment - dosage of 1000 thousand. Units per 1 g, includes such excipients as lanolin and petrolatum,
  • vaginal suppositories - dosage 250, 500 thousand. UNITS, excipients include propyl ether of paraoxybenzoic acid, food citric acid, Witepsol H-15, Witepsol W-35,
  • rectal candles - dosage 250, 500 thousand units, excipients are the same as those of vaginal suppositories, plus liquid paraffin.

Possible side effects and contraindications

When taking Nystatin may have side effects such as allergies (redness and rash on the skin, swelling), disorders of the gastrointestinal tract, nausea, vomiting, tachycardia, chills, and disorders of hearing or vision. If any of these symptoms occur, the use of the drug should be stopped immediately.

It is not recommended to take the drug during pregnancy and breastfeeding. It is prescribed in rare cases exclusively for local therapy. Since suppressed immunity during pregnancy is not uncommon, during this period there is an increased risk of thrush. In this case, the doctor will select a more appropriate means to combat this disease.

Other contraindications include:

  • severe liver dysfunction,
  • pancreatitis,
  • peptic ulcer and duodenal ulcer,
  • hypersensitivity to the drug.

Using candles to eliminate the disease in women

Молочница у женщин проявляется следующим образом: возникает зуд и отек слизистой половых органов, из влагалища идут белые творожистые выделения, которые могут иметь неприятный запах, боль и жжение сопутствуют мочеиспусканию и половому акту, в некоторых случаях повышается температура. В таких условиях вагинальные свечи — наиболее подходящее средство для лечения.

Candles with nystatin for thrush are a very effective drug for local therapy in both acute and chronic forms of the disease. Due to the fact that they act directly on the vaginal mucosa, the active ingredient of the drug penetrates deep into the tissue and remains there for a long time, killing pathogenic fungi. Candles need to be injected at least twice a day, while not forgetting the preparatory procedure, which increases the effectiveness of the treatment: you should wash or douche with a weak solution of potassium permanganate or infusion of herbs (chamomile, sage, calendula, string, etc.) in order to remove plaque and discharge. The course of treatment in this way is one and a half to two weeks.

In some cases, it may be necessary to use rectal suppositories - when the infection has struck the rectum and spreads to the intestines. The use of rectal suppositories is justified both for the treatment of women and men. Rectal suppositories are also inserted into the anus at least twice a day, unless the doctor has prescribed another.

Ointment for the treatment of thrush in men

The danger of developing thrush in men is that the disease can be almost asymptomatic in men. You should be alerted by such manifestations as an unpleasant smell, itching or burning of the genital organ, white bloom or redness of the glans penis and foreskin. There are no discharges.

In such a case, local treatment with nystatin ointment is sufficient: the agent is applied with a thin layer twice or three times a day to the head of the penis and the foreskin, having performed hygiene procedures before this. The course of treatment is on average 10 days.

Nystatin ointment is also used for prophylactic purposes during the week after the end of the main course of treatment, applied to the affected area once a day.

In this case, we note that although there is a likelihood of infection with candidiasis from an infected sexual partner, thrush is not a venereal disease, as it can develop as an independent ailment. In the absence of symptoms in a partner, his treatment is optional.

Nystatin tablets in complex therapy

Nystatin tablets are used if the success of using exclusively local products with nystatin is unlikely. This happens when the disease becomes very acute, neglected or systemic in nature, spreading to different organs of the human body.

The decision to take Nystatin tablets inside must be taken by the doctor, prescribing the dosage accordingly. Self-treatment in this case is unacceptable. Nystatin tablets are very effective, their active substance is poorly absorbed into the bloodstream and almost everything is removed from the body (which means they have little toxicity), but you should be aware of possible side effects. Usually prescribed pill 3-4 times a day, regardless of the meal. The duration of the course depends on the form and neglect of the disease.

For the prevention of tablets Nystatin drink twice a day for at least a week. This is especially true when taking broad-spectrum antibiotics.

With the defeat of the oral candidiasis nystatin tablets are taken several times a day, not swallowing, but dissolving in the mouth.

Features of treatment of candidiasis in children

Children are susceptible to the development of such diseases, as their immune systems are not yet strong. The most frequent places of localization of candidiasis in children is the oral cavity and nasopharynx. In this regard, Nystatin prescribed to children from an early age, including newborns.

The most common treatment is mouth rinsing with nystatin solution. To do this, 1 tablet of the drug (250 thousand. IU) is ground into powder and diluted with boiled water at room temperature (200 ml). Rinse your mouth 3-4 times a day with this solution, or lubricate the mouth with a cotton swab moistened with a solution (for infants).

If the doctor has determined the need for oral pills, their dosage is determined based on the age of the small patient: up to a year, from one year to three years, from 3 to 13 years old, older than 13 years. Tablets are drilled 3-4 times a day, drinking plenty of water, regardless of the meal.

For girls under 18 years old, vaginal suppositories are not prescribed, limited to tablets and ointment for nystatin-based topical use.

Additional recommendations for drug treatment

During the use of products containing nystatin to ensure the effectiveness of therapy should follow these rules:

  • eliminate alcohol: it affects carbohydrate metabolism, stimulates the reproduction of Candida fungi,
  • the appointment together with Clotrimazole leads to a decrease in the concentration of the latter in the blood and a decrease in its therapeutic effect,
  • follow a diet - limit sweets and dairy products, increase the amount of fiber,
  • with reddening of the skin, rash, stop treatment,
  • It is not recommended to use the drug in the form of candles during menstruation,
  • It is recommended for the duration of treatment to refrain from intimate life.

The interaction of Nystatin with other drugs

Nystatin interacts with few pharmacological drugs, since it is almost "transit" through the human body. It is not absorbed and does not accumulate, does not penetrate through the mucous membranes into the blood, and does not undergo the process of any biotransformation.

The only exceptions are some drugs with which it can interact and lose its activity or reduce the effectiveness of a particular drug.

  • Tetracycline with Nystatin - well complement each other, providing a pronounced antimicrobial and antifungal effects,
  • Clotrimazole with Nystatin - Clotrimazole activity decreases,
  • Polymyxin and Nifuratel - enhance the action of Nystatin,
  • antacids with aluminum, calcium, magnesium (Almagel, Maalox, etc.) - reduce the activity of Nystatin,
  • indirect anticoagulants (Warfarin, Acenocoumarol, Fenindione, Coumadin, etc.) - their activity under the influence of Nystatin decreases, their dosage increase is required,
  • bactericidal antibiotics (penicillins, cephalosporins) - their effectiveness decreases when interacting with Nystatin,
  • Chymotrypsin - the effectiveness of Nystatin increases,
  • estrogen-containing oral contraceptives (Marvelon, Logest and others) - their effectiveness under the influence of Nystatin may decrease, and the risk of breakthrough (intermenstrual) bleeding increases,
  • when combined with nystatin retinol drugs - increases the risk of increased intracranial pressure.

Nystatin candles from thrush - reviews

Probably every woman faced thrush at least once in her life. I have it manifested as a reaction of the body to stress and weakened immunity. When once again this attack came to me, I decided to try the candles with nystatin from thrush. I set the first one for the night. In the morning it became much easier for me - the itch was almost gone! In order for the symptoms to pass completely, I applied them 3 days in the morning and in the evening, and then another 2 days (just in case). I do not know if this is connected with candles or not, but thrush has not returned to me for a long time! Candles recommend!


Your attention is a review of the antifungal agent nystatin suppositories with which I treated thrush. Unfortunately, the experience is not entirely successful. Gynecologist prescribed them to me after Candid sown in a smear. The course was long for 14 days, and in addition to the candles, it was necessary to drink Nystatin tablets, as well as be treated by the husband. I did everything as prescribed by the doctor. Symptoms did not disappear immediately, only by the end of the week from the start of treatment. In 14 days everything went away, and the tests returned to normal. But after a while, everything happened again. Less than a month. As for the nystatin candlesticks, I can say that they act, but not for long. Not the most effective.


Nystatin more than once helped me get rid of thrush. They [candles] are very inexpensive, for me a penny. I bought them at the pharmacy and started the course. The next day, all the symptoms of thrush are gone! Now Nystatin is a frequenter of a resident of my first-aid kit, six months have passed and I do not know what a thrush is ... Therefore, I recommend the girls to these candles! They do not harm you and cost a penny.


The first time I encountered thrush 3 years ago, and so she tormented me, which angered me to horror. I remember the first time I went with this problem to the gynecologist, and Nystatin and Flucostat wrote me candles. The candles themselves were not expensive. 10 candles for 10 days. Put candles and the effect was not. At first I thought that it could be the way it was, no wonder the course was 10 days, but, alas, after the course there was no change, the thrush was still terribly tormented. Therefore, the gynecologist had to go again to appoint a new treatment. It was terribly sorry spent time on these candles.


Nystatin is a fairly safe remedy for the treatment of various forms of candidiasis, which has proven its effectiveness over the years. However, you should take into account contraindications and closely monitor the occurrence of possible side effects while taking the medicine.


How to take Nystatin with thrush, is there a contraindication to the drug? Thrush is a common disease that causes discomfort and requires effective treatment. There are many antifungal drugs on the pharmacological market. But the proven tool for years is Nystatin.

Nystatin from thrush can be used internally, intravaginally. The medicine has various forms of release: rectal, vaginal suppositories, tablets, ointment. An experienced doctor will tell you how to take Nystatin, individually for each patient.

The drug is prescribed for vaginal candidiasis, stomatitis, intestinal fungus.

Characteristics of the drug

The composition of the drug is the active ingredient - nystatin, which refers to antibiotics. Tablets stop the multiplication of infection, because the uncontrolled growth of yeast fungi is the cause of thrush.

Component molecules enter the cell membranes of the fungus and envelop the bacterium with a film. After that, the pathogens stop growing and die.

In small doses, nystatin with thrush prevents the growth of the fungus Candida, and a large dosage of the drug destroys the infection completely.

Experts recommend the treatment of thrush Nystatin acute and chronic forms of the disease.

In the treatment of candida Nystatin is not addictive, the resistance of bacilli is produced slowly.

The drug has a different form of release:

  • pills,
  • nystatin ointment for thrush,
  • candles from thrush.

What medicine will help the doctor to choose, he will recommend an effective therapy, determine the dosage and duration of the drug. Instructions for use will help to achieve rapid recovery.

Each form of drug release has its own instructions:

  1. Tablets are available in 200 and 500 thousand IU, can be used for treatment and prophylactic purposes. More often it is recommended to drink tablets for candidiasis of the intestine, the defeat of the genital fungus. It is permissible to take the drug about 6-8 times a day.
  2. Ointment for thrush often recommended for men. In this disease, it is necessary to undergo treatment to both partners, otherwise there will be no positive result. Intimate intimacy for the period of local treatment should be abandoned or condoms should be used. Lubricate the affected areas twice a day - in the morning and in the evening after a shower. If the disease is a mild form of the disease, seven days of treatment are sufficient; in more advanced cases, prolong therapy to two weeks. If during the use of Nystatin with thrush there are side effects, it is better to refuse the drug and consult a doctor. The doctor will replace the drug to prevent serious complications.
  3. Candles with Nystatin for thrush are an effective treatment for vaginal candidiasis. The active substance locally affects the mucous membrane, relieves unpleasant symptoms and prevents the multiplication of the infection. Nystatin candles with thrush vaginal and rectal exist. Vaginal suppositories are used in conjunction with ointments to speed recovery. To introduce the drug should be after water treatments, before bedtime. The course of therapy lasts about fourteen days. It is also permissible to use an antifungal agent for prophylaxis.

Rectal suppositories are recommended to be taken in case of a fungal infection of the rectum. The drug is prescribed by the doctor after examining the patient, the doctor determines the duration of the course of therapy. More often, it is recommended to inject the drug into the anus for about two weeks.

Nystatin is not recommended for pregnant women while feeding a baby, as well as for young children without consulting an experienced specialist.

At the first symptoms of the disease: itching, burning and discomfort, cheesy plaque, pain, a specialist prescribes vaginal suppositories. To enhance the result, it is recommended to use ointment in the complex. The tool is used in men, lubricating the vulva in the morning and evenings.

Compliance with all recommendations will allow to get rid of the fungal infection in ten days.

If candidiasis has acquired a chronic form, it is necessary to take antibiotics. The dosage and treatment course is determined by the doctor individually for each patient.

The neglected form of the disease requires several courses of anti-bacterial therapy. Antibiotics need to drink for ten days, take a break for two weeks, and repeat the therapy. To control the effectiveness of treatment, it is necessary to pass a vaginal smear.

To make recovery faster, it is important to follow these guidelines:

  • refuse alcoholic beverages for the period of treatment,
  • rectal and vaginal suppositories are best not to use during menstruation,
  • abandon intimate relationships, especially since sex causes pain and discomfort,
  • abandon flavored personal care products, fitting synthetic underwear,
  • to consult with a doctor while taking other medications, you should not use Clotrimazole with Nystatin - the effectiveness of the means decreases.

Nystatin is recommended to take in acute and chronic candidiasis, lesions of the intestinal fungus.

But like any drug, nystatin means has contraindications, it is necessary to refuse the medication:

  • with individual intolerance of the active component,
  • allergic manifestations
  • pregnancy and breastfeeding,
  • diseases of the gastrointestinal tract.

Some patients have adverse reactions. Candles can cause itching and burning, rash, swelling, redness of the genitals are rarely observed.

Tablets can cause nausea, vomiting, diarrhea, pain in the abdomen. Such adverse reactions require consultation with a doctor. The doctor will adjust the dosage or replace the drug.

Features antifungal agents

Self-treatment of thrush can lead to negative consequences. Nystatin is released in the pharmacy by prescription.

Feature of the drug is:

  • not addictive in a patient
  • treatment with an antifungal agent is important to hold both partners to see the effectiveness of therapy,
  • The drug is stored for about two years, in an inaccessible place for small children.

In order to avoid negative consequences, it is necessary to undergo examination by a gynecologist before treatment. Non-compliance with the recommendations of a specialist or premature interruption of therapy may aggravate the situation. Untreated illness causes serious complications. If the fungus begins to multiply rapidly, it affects other organs: the rectum, the gastrointestinal tract, the urethra.

Antifungal agent is recommended for pregnant women if the benefits of therapy are much higher than the risk to the development of the baby.

A small child with stomatitis can lubricate the oral mucosa with Nystatin after consultation with a pediatrician. The doctor will set the exact dosage according to the weight of the child.

The course of therapy lasts about fourteen days. After two or three days, the patient is relieved. But even if the symptoms disappear, it is forbidden to stop treatment, the untreated disease causes serious complications.

After the course of therapy it is necessary to pass laboratory tests to make sure that the fungal infection has disappeared.

The efficacy of the drug is proven by long use. Price Nystatin different democratic and accessible to everyone. Tablets can be purchased for about 30 rubles, depending on the number and dosage of tablets. Ointment costs more than 50 rubles, candles - about 35-40 rubles.

How to take Nystatin with thrush

Nystatin is an excellent treatment for thrush, used for many years, which once again proves its effectiveness and reliability. Today, it is unfairly forgotten, because modern pharmacology offers so many modern and diverse products that have both pluses and minuses. По этой причине Нистатин, имеющий достаточно небольшую стоимость, стал применяться все реже и реже.

Применение Нистатина при молочнице

  • 1 Показания к приему
  • 2 Специфика терапии Нистатином

Нистатин – это сильнодействующий противогрибковый препарат, который необычайно эффективен в процессе борьбы с дрожжеподобными кандидозными грибами. The main active ingredient of this drug is an antibiotic that represents a polyene group. This type of antibiotic has a detrimental effect on the cells of the fungus, but does not apply to bacteria. The essence of Nystatin in the treatment of candidiasis is based on the fact that between the styrene molecules appears a strong link. This contributes to the fact that the protective shell of candida fungus significantly weakens. As a result, the path to the promotion of free ions opens, and this causes the death of fungal cells.

Nystatin effectively reduces the intensity, the rate of reproduction of fungi. It is important to note that the antifungal agent has a selective effect, therefore it has a targeted effect on candidiasis.

Indications for admission

Nystatin is a popular medicine that helps to cope with the painful manifestations of candidiasis. For chronic vaginal thrush or in the exacerbation phase, you can use suppositories, tablets or Nystatin ointment.

The treatment by Nystatin of dysbacteriosis with candidal character is considered appropriate. This form of thrush can occur after surgery or long-term use of antibacterial drugs.

Nystatin can be used in the treatment of candidiasis of the genital organs, oral cavity and gastrointestinal tract, with skin lesions. Candles with nystatin for thrush are recommended for the treatment of vaginal candidiasis in women, as well as vaginosis, which takes a bacterial character.

Nystatin is also used for prophylactic purposes to prevent possible complications that are directly related to the fungal infection. Apply the ointment before going to the sauna, bath, pool, so you can protect yourself.

The specifics of therapy with Nystatin

Nystatin is available in the form of tablets, ointments and suppositories. Candles from thrush can be not only vaginal, but also rectal.

Nystatin tablets can be given not only to women, but also to men.

It is forbidden to use Nystatin without a prescription, as there are many contraindications to their reception. This drug is not recommended for pregnant and lactating women, people with gastric and duodenal ulcers, in the presence of pancreatitis, allergies and pathology of the kidneys.

The drug has side effects: nausea and vomiting, allergies, indigestion. If you find side effects need to stop taking Nystatin and visit a doctor.

Nystatin suppositories are very effective in the treatment of vaginal candidiasis. The drug has a local effect on the vaginal mucosa. Suppositories can be prescribed after the results of laboratory tests are known and an inspection is carried out. The total duration of the use of candles - about 14 days. It is desirable to conduct a comprehensive treatment.

Ointments are applied to the external genital organs, as well as the skin of the inner part of the thighs. Before manipulation you need to thoroughly wash the crotch, using soap.

As for the nystatin rectal suppositories, they are indicated in case of a serious lesion of the large intestine with a candidosis fungus. In most cases, the rectal suppository is an integral part of complex therapy in combination with tablets. The treatment lasts about 10-14 days, then analysis of the tank sowing is done. Contraindications: lactation and pregnancy, idiosyncrasy.

Nystatin is a very powerful antifungal drug, but it should be taken only as prescribed by your doctor.

General drug description

Nystatin tablets for thrush are available in two dosages - 250 000/500 000 IU. The main active ingredient of the drug is effective against yeast-like fungi Aspergillus and Candida.

Small drops have a yellow color with a pronounced smell of vanilla and bitter taste.

Treatment regimen

Nystatin tablets for thrush are prescribed for both children and adults. The dosage and treatment regimen will be slightly different.

About tablets Nystatin instructions for use contains the following information:

  1. Adults and children from 13 years old - 1 tablet (50 000 IU) up to 4 times a day or 1 tablet (250 000 IU) up to 8 times in 24 hours.
  2. Children from 5 to 12 years old - 1 tablet (250 000 IU) 4 times a day.
  3. Children from 1 year to 5 years - 1 tablet (250 000) once a day.
  4. Infants - ½ tablet (250 000 IU) per day.

The minimum course duration is 10 days, the maximum is 14 days. In the recurrent form, the course of therapy is repeated after a week break.

Adverse reactions

Usually the drug is well tolerated without causing side effects, since it is practically not absorbed by the intestines. In rare cases, taking pills can trigger the following effects:

  • vomiting and diarrhea,
  • skin rash and itching
  • temperature rise.

More rarely, an antimycotic provokes the reproduction of pathogenic fungal flora, which produces resistance to the therapeutic component. In this case, immediate withdrawal of the drug is required.

How effective is “Nystatin” for candidiasis?

Recently, doctors have preferred other oral drugs for the treatment of candidiasis. This is due to the fact that antimycotic began to show less efficiency, because the fungi developed resistance to nystatin. In addition, the course of drug treatment is quite long, unlike the pharmaceuticals of the new generation, which can cure the disease in 3-7 days.

To increase the effectiveness of the oral release form, you should combine antimycotics with ointments and nystatin suppositories.

Other forms of Nistain release

The drug is also available in the form of ointments, which is used in the treatment of balanoposthitis in men.

Also, antimycotics are produced in the form of suppositories for rectal and vaginal administration for vaginal candidiasis, as well as for anal thrush.

Nystatin: analogues

According to the active substance, Nystatin has no analogues. According to the pharmacological action of the drug is similar to "Fluconazole." This medication is considered today the most effective drug that is used for candidiasis.

The main active ingredient in nystatin is a polyene antibiotic, the main mechanism of action of which is the binding to specific molecules (complex sterol molecules) in the membranes. As a result of this interaction, the protective function of the cell membrane is disrupted, an uncontrolled flow of ions into the cell occurs, which ultimately leads to its death.

In low concentrations it slows down and in high concentrations it kills the cell of the fungus.

The main spectrum of action: yeast-like fungi (especially in relation to Candida alb.), Aspergillus microorganisms.